Benefits of Molecular Hydrogen 101 by Dr. EnQi & Tone

Benefits of Molecular Hydrogen 

The basics are there, hydration.

Yes, you are going to be hydrated when you drink water loaded with Molecular Hydrogen and get a full round of minerals in your diet; that is to be expected. When you are thirsty and need a great way to give your body the water that it needs, this should be your first step. Problem, its almost unheard of and largely unavailable.

It will rehydrate your body and cells, allowing you to feel much better and to avoid the dangers of dehydration. Of course, Molecular Hydrogen does not stop there. It may be great for the basics, but it gives you much more than just that. While the hydration itself is great, and better than other options, another point of this is the weight loss. When taking Mommatomix and consuming medical grade Molecular Hydrogen, you will be able to lose weight healthily and more quickly than you could otherwise. This is a great addition to your life when you want to be healthier and look better as a whole. One huge benefit to this is how it is anti-aging and anti-inflammatory. This is huge for water and it is a great way to give your health and appearance the boost that it needs.

Molecular Hydrogen is Anti-Ageing Anti-Viral Anti-Bacterial all at the same time simply by being Anti-Fat!!!

Molecular Hydrogen produced by the Nexus Smart 9p water ionizer or produced with Mommatomix will help you to avoid dangers in the future along with annoyances with aging. As the years go by and life happens, you will be able to look beautiful and be healthy. While it can not protect you against everything, it does a great job and it is highly effective. Molecular Hydrogen is the fountain of youth because it is the foundation of Biochemistry and the foundation of Bioelectromagnetism & Charge. For those who may not know, too much acid forming elements can be bad for the body. Molecular Hydrogen & Mommatomix are the solutions to this problem. It will balance out your body so that it is not overly acidic. This will help you to be healthier in a way that other options can not offer, and in a way that is completely natural and healthy.

Molecular Hydrogen has many health benefits for our bodies however we need to maximize our mineral intake in order for the maximum effect to happen. Over 200 of the most basic Bio-Molecules are created and/or regulated by Molecular Hydrogen. When combined with the right types of minerlas via Mommatomix (hin hint lol) it will hydrate your body effectively and it will be good for you overall.

The taste of the Molecular Hydrogen Water is better than any other regular or tap water in the market. The Nexus Smart 9p Molecular Hydrogen Water Machine and/or Mommatomix can be purchased at Onetone.earth 

Almost 200 human disease models had been clinically demonstrated to benefit from Molecular Hydrogen and almost 1000 scientific articles have been written on Molecular Hydrogen. Good Bacteria work via Molecular Hydrogen and Infrared production for the body. The endoplasmic reticulum responsible for most protein production and folding does not function without optimal levels of Molecular Hydrogen. Molecular Hydrogen increase all of the major Antioxidant markers like SOD, GPx, Glutathione etc… Molecular Hydrogen is the gas in the engine of the NRF2 Antioxidant system and the most effective Mitochondrial Antioxidant you can incorporate into your diet or supplement regimen.

The biggest Major Break through which is why my Dad is the Greatest Of All Time is because Resveratrol as a plant based analoge for tyrosine up-regulates the Molecular Hydrogen pathway in exactly the way he predicted over 10 years ago. Get your Resveratrol from Histonic his brilliant formula that he couldn’t have completed without KT the Arch Degree.

Here’s a lil science to help you understand BioChemistry…

Hydrogen Reduces Oxygen Oxidizes. Its very general but it’ii help you with the coming information.

Molecular Hydrogen Intro by Dr. EnQi & Tone

Alkaline Water is a Fraud Molecular Hydrogen is the Truth

Water is life itself.

Molecular Hydrogen is a basic necessity to Living Biochemistry. All living organisms need Molecular Hydrogen in order to survive. For the proper functioning of the human body, water (Molecular Hydrogen) intake is essential, without water our system collapses. Some people are deprived of this precious gas that we can obtain just from our faucet in the comfort of our homes, while knowing that for others water is essential to be alive, but it is scarce.

Today it is well-known that our water is full of pollutants.

All the atmospheric releases of radioactive pollutants on the air, radiative rainfalls, smog, industrial waste in lakes, rivers, oceans and landfills, let our natural sources become a catastrophic disaster. All the chemical components and nuclear contaminants are reaching all the environments that are no longer natural or in harmony, poisoning our air, rain, glaciers, land, and water This results in a rise in world-wide health threats. There is a lot of information around Molecular Hydrogen and its properties, but in reality, we are not drinking safe and clean water. Our water no longer structures into H3O2 at a optimal rate and we are sick, DEHYDRATED. Dehydrated means lacking Molecular Hydrogen not lacking “water”. We need to look for ways to protect our body and environment from those irreversible and damaging attacks. We can take advantage of some particular sources by researching Dr. EnQi (my dad) or Mona Harrison. This is important as it directly influences 80-99 % of our body and also helps the planet Earth which is mostly water.

We need high amounts of Molecular Hydrogen!!!!

Normally, the pH of water is 7 and it is neutral, but the pH of alkaline water is alkaline because it has more negative ions than positive ones, creating this optimal medium of energy carrier into your system. Our bloodstream along with other elements inside of our body work naturally through the physiological functions that effectively regulates the pH of our body. A human body with a neutral pH is considered to have the ideal health condition. Anything below 7 is acidic as it imbalances the body creating sickness. Above of 7 is alkaline and this state is beneficial due to the fact that it neutralizes the acidity in the body, and neutralizes harmful waste substances inside the body, to slow or even reverse, acidification and oxidation. Alkaline water promotes better blood circulation, helps prevent disorders from the immune system, allows nutrients to be absorbed more efficiently, and boosts your metabolism. STOP!!!!! All of the above is a lie!!!! Its not the “PH” that confers a health benefit, its the amount of Molecular Hydrogen in the water that heals. One of the best ways to keep the pH to a neutral and balanced level of 7.0 is eating Vegan and taking Herbs.

The average water consumption recommended is 8 glasses of water a day; at least half the daily water consumption, for example 4 glasses per day, should be alkaline water. This is the big secret my dad hides of Mommatomix and why its soooo powerful, Molecular Hydrogen.

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How To: Plant Based Magnesium

Chlorophyll – Potent Porphyrin

Porphyrins are a group of heterocyclic macrocycle organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (=CH−). The parent porphyrin is porphine, a rare chemical compound of exclusively theoretical interest. Substituted porphines are called porphyrins. With a total of 26 π-electrons, the porphyrin ring structure is often described as aromatic.[1][2] One result of the large conjugated system is that porphyrins typically absorb strongly in the visible region of the electromagnetic spectrum, i.e. they are deeply colored. The name “porphyrin” derives from the Greek word πορφύρα (porphyra), meaning purple.

11 Amazing Health Benefits Of Vervain

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Blue Vervain, also known as Simpler’s Joy, is an exotic herb that possesses a fascinatingly vast medicinal history. It is one among the 250 members of the Verbenaceae family and is popularly called Vervain. This plant with violet flowers can be seen spread across Europe and America. Read on to know about blue vervain benefits here.

The Vervain was earlier used as an aphrodisiac, but today it is a well-known tranquilizing agent and antidepressant. It is also known to offer countless benefits to women. This vervain herb has made a name for itself with its countless beneficial properties for mankind. Read on to know more about this herb and its benefits:

Blue Vervain Benefits:

Check out here some of the top benefits of blue vervain in detail here.

1. Natural Mood Enhancer:

The power of vervain to ease the feelings associated with anxiety and stress is well-acknowledged. Drinking a cup of vervain tea has a soothing effect on the central nervous system that in turn triggers a sensation of calmness and relaxation. Thus, this herb has been widely used to aid people suffering from depression and stress. Vervain is also believed to be effective in easing post-traumatic stress as well as insomnia. Just drink a cup of warm vervain tea 30 minutes before you hit your bed for a good night’s sleep. A natural tranquilizing agent, it is a good antidote for restlessness and irritation.

2. For A Healthy Gut:

This herb, in the form of tea, can be used as a natural drink to ease digestive disorders and keep the gut healthy. It has been a sought after remedy for various common problems affecting your tummy, including bloating, cramps, and flatulence. A natural remedy for vomiting and diarrhea, this herb is also known to boost nutrient absorption. Get rid of the worms and toxins from your stomach with this herb. The herb can be used as a good laxative as well. Studies suggest that regular use of about 2 oz to one quart of this vervain decoction can ease vomiting, thus relieving you from stomach pain. This herb decoction, when applied externally, is also known to cure piles.

3. For Better Oral Health:

Give your gums and teeth a dose of goodness by chewing this herb regularly. A very effective traditional medication for bleeding gums, this herb is also known to ease the pain and redness experienced due to mouth ulcers.

4. Natural Analgesic And Anti-Inflammatory Agent:

Vervain is known to possess innate analgesic and anti-inflammatory properties. This makes it an efficient cure for cold and fever. Along with easing body pain and lowering the temperature levels during episodes of fever, it is also known to provide immense relief from migraine and sinusitis. A natural stimulant and revitalizing agent, this herb is also used as a tonic to overcome the weakness experienced after a severe bout of fever. It is also known to eliminate the phlegm from throat, thus offering relief from continuous bouts of cough.

5. Natural Antispasmodic Agent:

This ancient herb is known to possess antispasmodic properties. That is why it is highly recommended by traditional physicians as a medication for muscle cramps, pains, and spasms. It can be used as a poultice to ease pain associated with medical conditions such as ear neuralgia and rheumatism.

6. Good For Women’s Health:

Packed with intense mood improving properties, this herb helps in easing the anxiety and mood swings experienced by women during the premenstrual period. Vervain is also used to induce menstrual cycle in women whose periods has been delayed.

The herb has the potential to trigger uterine contractions, and hence, it can be used to induce labor and hasten child birth. Studies also indicate that using vervain aids in improving lactation levels naturally after delivery.

7. Natural Tonic For Your Liver:

This herb is known to bestow the liver with various benefits. The anti-inflammatory and anti-spasmodic properties of this herb enable it to be used effectively in the treatment of jaundice by cleansing the liver.

[ Read: Healthy Foods for Liver ]

8. Antidote For Malaria:

The ancient Chinese medicine suggests the use of the roots of Blue Vervain as a natural cure for malaria.

9. Blue Vervain Benefits For Skin:

The natural astringent and anti-inflammatory properties of this herb enables it to be used as a natural remedy for various skin infections. Studies also suggest that this herb is useful in safeguarding wounds from infections. It also helps to get rid of the toxins inflicted from insect bites.

10. Good For Kidney Stones:

Just prepare an infusion by steeping 1 tbsp dry blue vervain leaves in one pint boiling water for 10 minutes. Consume about 6 tbsp every day, spread over 6 doses, to get rid of urinary bladder infections and kidney stones.

[ Read: Home Remedies for Kidney Stones ]

11. Natural Detoxifying Agent:

The herb is known to induce sweating and one can take the help of this herb to eliminate toxins from their body via sweat. This also helps the skin look fresh and young.

What Is The Recommended Dosage?

While there are no established recommended dosages for this herb, traditional medications suggest a daily use of 2 to 4 grams as an infusion.

Contraindications:

  • Even though blue vervain is known to be a storehouse of benefits, it should be used in restricted amounts. Excessive consumption of this herb can trigger vomiting, leading to dehydration.
  • Since the herb is known to induce uterine contractions and lactation, pregnant women are advised against consuming the same during the initial stages of pregnancy.

So, this was about vervain uses in different ways. Blue vervain can be used in various forms – powder, tincture, capsules, tea, and flower essence, to name a few. 

Hope you liked our post on vervain benefits. However, it is always advisable to consult your homeopathy physician or an herbal specialist and take his/her advice before you start consuming the herb.

Burdock Root Detoxes Blood, Lymph System + Skin

Burdock root - Dr. Axe

What if I told you that a certain plant’s roots could detoxify your blood, lymphatic system and skin? Would you be interested? Then you should know about burdock root.

Burdock root has been valued across continents for thousands of years for its ability to purify blood and cool internal heat. Internally and externally, it has potent anti-inflammatory and antibacterial effects on the human body. Recent studies also show that burdock contains phenolic acids, quercetin and luteolin, which are all powerful, health-promoting antioxidants. (1)

Similar to dandelion tea, you can make burdock root tea, and it can also be found in supplement form or be eaten as a vegetable. What does it taste like? Burdock has a pleasantly crunchy texture and an earthy, sweet flavor that’s similar to lotus root or celeriac. Read on to find out just how awesome burdock root truly is, including the medicinal uses of burdock in treating serious chronic diseases like cancer and diabetes! (2)


9 Amazing Burdock Root Benefits

The benefits of burdock root are wide-ranging and sure to impress. Here are some of the top ways it can seriously improve your health.

1. Blood Purifier

In traditional herbal texts, burdock root is described as a “blood purifier” or “alterative” and was believed to clear the bloodstream of toxins. (3) Burdock root has active ingredients that have been found to detoxify heavy metalsfrom the blood, improving organ health and the health of the whole body. It also promotes blood circulation to the skin surface, which improves skin health.

2. Lymphatic System Strengthener 

Essentially, the lymphatic system is the the body’s inner “drainage system,” a network of blood vessels and lymph nodes that carry fluids from tissues around the body into the blood and vice versa. If you can make your lymphatic system stronger, then you can help your body ward off all kinds of disease and serious health issues. Burdock root helps induce lymphatic drainage and detoxification. As a natural blood cleanser, it has a wonderful effect on the lymphatic system. (4)

3. Natural Diuretic

Diuretics stimulate the kidneys and help the body get rid of excess fluid, mainly water and sodium. Burdock root is a natural diuretic so through burdock consumption, you can naturally and easily help your body to eliminate excess water by increasing urine output. By elevating the rate of urination, burdock root can help to remove waste from the blood and body. (5)

If you have issues with fluid retention, you should ask your doctor about trying burdock root before resorting to prescription products.

4. Skin Healer

Topical products containing burdock root have offered relief from pesky skin issues for ages. From acne to eczema to psoriasis, burdock root is known to calm and heal these common skin issues. Consumption of burdock has also helped many people with skin issues through its blood-cleansing and internal cooling abilities.

Scientific studies have even shown that burdock extract can even improve the clinical signs of aging skin! One 2008 study showed that topical treatment with a natural burdock extract significantly improved the metabolism of the dermal extracellular matrix and led to a visible wrinkle reduction. (6) For good reason, we’re likely to see burdock root being used more and more in skin care products, especially for mature and dry skin.

5. Defend Against Diabetes

Burdock root contains inulin, a soluble and prebiotic fiber that helps improve digestion and lower blood sugar, making it an excellent choice for people trying to naturally manage their blood sugar. In Europe, the fresh root is used for lowering blood sugar, its inulin content making it particularly suitable for diabetes. Animal studies have also shown burdock root’s ability to decrease the severity of diabetic complications, especially diabetic retinopathy. (7)

 

Burdock root nutrition - Dr. Axe

 

6. Combat Cancer

European physicians of the Middle Ages and later used burdock to treat cancerous tumors (as well as skin conditions, venereal disease, and bladder and kidney problems). Many herbalists today say burdock root can stop cancer cells from metastasizing, making it a potential natural cancer treatment. In fact, animal studies of mammary, colon and pancreatic cancer have shown promise for burdock’s ability to fight against cancer. (8)

One big reason burdock shows promise for naturally fighting cancer is the fact that it contains arctigenin. Arctigenin is a lignan found in certain plants of the Asteraceae family, including greater burdock (Arctium lappa), which has been shown to combat cancer cells by selectively stopping the proliferation of cancer cells and by inhibiting the cancer cells’ production of particular proteins (NPAT proteins), hence crippling cancer’s ability to reproduce. (9)

Another study found that arctigenin was a cancer-specific phytochemicalthat killed human lung cancer cells, human liver cancer cells and human stomach cancer cells. (10) Studies like this are proving what many have believed for years — that burdock root is a seriously effective natural cancer fighter!

7. Improves Arthritis

Burdock root is known for its powerful anti-inflammatory abilities, even helping to soothe arthritis. A study published in the International Journal of Rheumatic Diseases showed that burdock root tea improves inflammatory status and oxidative stress in patients with knee osteoarthritis, also known as degenerative joint disease.

Subjects were given three cups of burdock root tea per day for forty two days and were then assessed for inflammatory markers, such as high-sensitivity C-reactive protein. The results showed that burdock root tea can significantly help people suffering from osteoarthritis by lowering inflammatory markers. (11)

8. Helps Treat an Enlarged Spleen

If you suffer from an enlarged spleen, burdock root can help. The spleen is a vital “guardian” organ that we rely on to keep the body free from infections, viruses and all kinds of dangerous pathogens. An enlarged spleen is a clear warning sign that the immune system is fighting hard to remove threats from the body but failing to do so because it can’t keep up with high demand.

Your spleen is in constant contact with your blood so as burdock root cleanses your blood, it also cleanses and protects the spleen. It can help the spleen because it improves blood quality as well as liver health, circulation and fights inflammation. Improving those four factors has a direct positive effect on spleen health so you definitely want to include burdock in your spleen-healing lineup. (12)

9. Fight Tonsillitis

Burdock root can help get rid of painful tonsillitisAcute tonsillitis is a type of inflammatory virus that causes tissues within the tonsils to become infected with harmful bacteria. Burdock root is helpful to tonsillitis because it increases wound healing, decreases inflammation, and helps to relieve coughs, sore throats and pain. (13)


Burdock Root vs. Dandelion

How exactly does burdock compare to dandelion? Both are members of the Asteraceae plant family and have been used in their entirety for traditional as well modern medicine for years.

Both burdock root and dandelion are excellent for diabetes and skin conditions. They’re also natural diuretics that are loaded with antioxidants. Dandelion is specifically excellent at cleansing the liver and protecting the bones while burdock is an amazing blood cleanser, which also makes it very helpful to liver health.

Burdock is also helpful for bones, particularly osteoarthritis. Dandelion is high in fiber as well as vitamins A, C and K, while burdock is equally high in fiber as well as vitamin B6, potassium and magnesium.

 

Burdock root vs. dandelion - Dr. Axe

 


Burdock Root Nutrition Facts

Burdock root (genus Arctium) is a genus of biennial plants in the Asteraceae(daisy) family that’s native to Northern Asia and Europe, but it’s now found throughout the U.S., where it grows as a weed. In Japan, it’s often called gobo root and is cultivated as a vegetable.

Burdock has large, heart-shaped leaves and bright pink-red to purple thistle-like flowers. It also has burrs that can stick to clothing or animal fur. The deep roots of the burdock plant are brownish-green or nearly black on the outside.

Burdock root is a slender, brown-skinned root vegetable that typically grows to be more than two feet in length. It consists primarily of carbohydrates, volatile oils, plant sterols, tannins and fatty oils.

Nutritionally speaking, one cup of burdock root contains about (14):

  • 85 calories
  • 20.5 grams carbohydrates
  • 1.8 grams protein
  • 0.2 gram fat
  • 3.9 grams dietary fiber
  • 0.3 milligram vitamin B6 (14 percent DV)
  • 0.3 milligram manganese (14 percent DV)
  • 44.8 milligrams magnesium (11 percent DV)
  • 363 milligrams potassium (10 percent DV)
  • 27.1 micrograms folate (7 percent DV)
  • 3.5 milligrams vitamin C (6 percent DV)
  • 60.2 milligrams phosphorus (6 percent DV)
  • 48.4 milligrams calcium (5 percent DV)
  • 0.9 milligram iron (5 percent DV)
  • 0.1 milligram copper (5 percent DV)

Burdock Root History & Interesting Facts

Burdock root has been used for thousands of years in Asia and Europe — and more recently in North America. In Japan, it’s a largely consumed vegetable, typically eaten fresh or cooked, and the young leaves can also be cooked like any other vegetable.

In Traditional Chinese Medicine, burdock fruit has been used continually for thousands of years. It’s typically associated with the lung and stomach meridians, is known to cool internal heat, and is commonly used for supporting skin health. In European folk medicine, an infusion of the seeds was often employed as a diuretic, enhancing health by supporting the processes of digestion and elimination.

Would you believe that the inspiration for Velcro actually came from the burdock burr? In 1941, the inventor, a Swiss engineer named Georges de Mestral, went for a walk in the woods and wondered if the burrs that clung to his trousers and dog could be turned into something useful. After nearly eight years of research, de Mestral successfully reproduced the natural attachment with two strips of fabric, one with thousands of tiny hooks and another with thousands of tiny loops. He named his invention Velcro and formally patented it in 1955. (15)

Burdock root has been used for centuries as a medicinal herb used to promote healthy hair, relieve scalp irritation and improve scalp condition. In Europe, burdock root oil, also known as bur oil, is commonly used as a scalp treatment to help prevent hair loss and get rid of dandruff. The thought is that all of those nutrients that help your skin, blood and organs could also improve your hair and scalp health.

7 Wonderful Parsley Health Benefits

The health benefits of parsley include controlling cancerdiabetes, and rheumatoid arthritis, along with helping prevent osteoporosis. Furthermore, it acts as a pain reliever with anti-inflammatory properties. It also provides relief from gastrointestinal issues such as indigestion, stomach cramps, bloating, and nausea, while helping to strengthen the immune system.

Parsley can be found throughout the year on the market. It is a cheap leaf that anyone can get a hold of. It is also a highly nutritious plant and has ample vitamins and antioxidants which can greatly improve our health.

What Is Parsley?

Parsley is an herb that originated in the Mediterranean region of southern Italy, Algeria, and Tunisia. This herb is known scientifically as Petroselinum hortense and Petroselinum crispum, and it belongs to the family Apiaceae.

It has been cultivated by man for more than 2,000 years and was highly regarded in Greek culture since it was used in various ceremonies. The Romans also used it in many ways. Pliny the Elder, a 1st century AD historian, wrote that it was consumed by people from all walks of life. At first, it was used only as a medicinal plant, but later on, it was consumed as a food. There are many myths and fables associated with the origin and growth of this plant in many Mediterranean and European cultures. The Greeks believed that it had sprung up from the blood of the fallen Greek hero Archemorus. Thus, Greeks started associating it with death and destruction, but in the Middle Ages, parsley was included in folklore medicines and it slowly gained popularity. This is possibly how the image of parsley as a health giver developed.

Parsley, a predominantly tropical plant, needs moisture and ample sunlight to grow. It is used as an herb, a green leafy vegetable, and as a spice. Actually, both the leaf and the root are used in Mediterranean and European cuisines. It is consumed in many different ways, including garnishing, salads, stocks, and sandwiches. The leaf is further divided into two more types: curly leaf and flat leaf. The root form is a new addition, which only began to be cultivated about 300 years ago, and was first grown in Hamburg, Germany. Nowadays, root parsley is steadily becoming more popular.

Parsley Nutritional Facts

The nutrients found in parsley include vitamin A, K, C, and E, thiamin, riboflavinniacinvitamin B6vitamin B12pantothenic acid, choline, folates, calciumironmagnesiummanganese, phosphorous, potassiumzinc, and copper. It is also a very good source of volatile compounds such as myristicin, limonene, eugenol, and alpha-thujene. Its leaves contain energy, carbohydrates, fats, and protein.

Health Benefits Of Parsley

Parsley, known for its use as a garnish, has many nutrients that provide health benefits to people. Some of these benefits include:

Anti-diabetic Properties

Traditionally, parsley was used as a medicine for diabetes in Turkey. In order to scientifically validate this claim, research was conducted at Marmara University in Istanbul, Turkey. The research showed evidence that diabetic rats that were given parsley actually showed a decrease in their blood sugar levels over a period of a month. The research indicates that it can be used for diabetic control.

Controls Rheumatoid Arthritis

Parsley has also been particularly effective against rheumatoid arthritis. Compounds such as vitamin C and beta-carotene found in the herb possess anti-inflammatory properties that help in controlling arthritis. Consuming it regularly is also believed to speed up the process of uric acid removal, which has been linked to symptoms of arthritis.

Anti-carcinogenic Properties

Zheng, Kenney, and Lam from LKT Laboratories in Minneapolis, Minnesota have extracted a compound named myristicin, which is a phenylpropane compound, from parsley oil extract. A preliminary investigation into the myristicin compound had revealed that it has anti-carcinogenic properties. Myristicin extract from the herb was only tested on rats and human application of this compound still remains to be seen.Parsley2

Anti-inflammatory Properties

Parsley has traditionally been used in the Mediterranean region for toothaches, bruises, insect bites, and rough skin. According to preliminary studies conducted at the King Saud University by Al-Howiriny et al., parsley displayed anti-inflammatory and anti-hepatotoxicity properties. The anti-inflammatory properties reduce internal inflammations, while the anti-hepatotoxic properties help to cleanse the liver.

Osteoporosis

Parsley is effective in cases of osteoporosis and is helpful in maintaining bone health. Osteoporosis occurs due to depleted levels of calcium in the bones and also due to lack of an amino acid called homocysteine. This amino acid can be broken down by the intake of folic acid. Due to this aspect, apart from dairy products and vegetables, parsley is regarded as one of the best sources of calcium. It also contains an appropriate amount of folic acid, which may break down homocysteine.

Diuretic Effects

For many centuries now, parsley has been used as a diuretic that helps in controlling various diseases such as kidney stones, urinary tract infections, and gallbladder stones. Edema is a medical condition where a patient retains fluid in the body more than what he or she is supposed to hold under normal circumstances. The body swells because of fluid accumulation. If you are afflicted by this condition, a few teaspoons of parsley juice can provide some quick relief. The roots of the herb are also very much useful in counteracting kidney stones. Adding its roots to boiling water and drinking it on a daily basis is known to be effective as a general cleanser for the body.

Strengthens the Immune System

The vitamins, minerals, and antioxidants found in parsley are helpful for strengthening immunity. Vitamins such as vitamin C, A, K, folate, and niacin each act on different aspects of the immune system. Vitamin A acts directly on lymphocytes or white blood cells, thereby increasing their effect. The chlorophyll contained in it has anti-bacterial and anti-fungal properties as well. Studies have shown that the herb contains antioxidant properties and antibacterial properties, making it an ideal source for various home remedies.

Risks Of Eating Parsley

Consumption of parsley especially in large quantities may have side effects and disadvantages. Some of them include the following:

Scientific Data on Hapi Hair

Hapi Hair is designed to help your body fight DHT build up, yeast/fungus, sweat gland atrophy, follicular disfunction and restore stem cell stability. Hapi Hair works not just for the hair and follicles on your head but every hair and follicle in as well as on the human body.

This kit is designed to Regenerate your Internal Hair Bio-Chemistry. Right now I’m using my Hpi Hair kit for hair, skin and nails nutrition while using the Mane Choice externally. My Hair has never been better!

Kit consists of two bottles of the new and improved Antonia’s Hair Villi ($65 FoTi aka Polygonum Multiflorum, Pumpkin Seed, Bhringaraj, Biotin, Silica, Tyrosine, Yucca & Keme) approx. 50 capsules each, 1oz YouMelanin ($35 Cilantro, Cloves, Milk Thistle & Copper Extracts), 2 bottles of Pink Lips ($50 Kelp, Chondrus Crispus aka Seamoss & Hydrangea) & a 1oz PhiEarn ($45 Yellow Dock, Stinging Nettles, Chaparral & Iron Extracts).

Hair Growth Starts Immediately in the first 28 Days

Hair Growth Becomes Exponentially Explosive after 120 Days (approx. 4 months)

Save time and MONEY!!! with the six month plus kit!!!

COMING SOON

 

Diagram of a hair follicle in a cross section of skin layers

 

What causes gray hair?

Scientists believe that senile hair graying, as the process is called, results from changes to enzymes in the hair follicle caused by naturally generated hydrogen peroxide. This is the same chemical that is used to bleach hair, only generated by the body itself due to free radical stress.

Hydrogen peroxide stops the production of the pigment called melanin, the same pigment that gives us our skin color. It does this by chemically changing the amino acid methionine so that an enzyme called tyrosinase cannot assist in the process of making the natural hair coloring pigments. Some people have a genetic variation that causes melanin to make pigments that cause the hair to look blue, instead of gray, in the presence of the chemically altered amino acid.

Graying hair isn’t just due to age.

Some people’s hair turns gray gradually, but sometimes the hair turns gray almost overnight. Typically there has been some kind of extreme stress on the body that disrupts the production of antioxidants that protects the hair (and other parts of the body) against free radicals.

Hair turns gray from the root up.

The biochemical process that causes hair to turn gray takes place during the “anagen” stage of hair production, inside the follicle, before the hair emerges from the skin. If you can’t dye the “roots,” you will never completely conceal gray hair.

Food Grade Yucca Schidigera extract has a considerable number of uses.  Natural plant saponins address many human maladies.  Yucca Schidigera extracts are from a plant in the Lillie family that is native to the Southwestern United States and Mexico.  Native Americans have used Yucca for hundreds of years to treat a variety of disorders.

MINERALS:  Iron, Magnesium, Manganese, Phosphorus, Selenium and Silicon

VITAMINS:  A, B complex, C

Daily doses of Yucca Schidigera extract has many human consumption uses: reduces arthritis, reduces Gout (lowers uric acid), reduces trans fat digestion, reduces carpal tunnel syndrome, reduces cholesterol,  restores cartilage, reduces colitis, reduces irritable bowl syndrome, prevents sore muscles, use as a shampoo to stop hair loss and restore hair growth, helps people to stop smoking, detoxifies the intestinal track. 

Use of silicon for skin and hair care: an approach of chemical forms available and efficacy*

Abstract

Silicon is the second most abundant element on Earth, and the third most abundant trace element in human body. It is present in water, plant and animal sources. On the skin, it is suggested that silicon is important for optimal collagen synthesis and activation of hydroxylating enzymes, improving skin strength and elasticity. Regarding hair benefits, it was suggested that a higher silicon content in the hair results in a lower rate of hair loss and increased brightness. For these beneficial effects, there is growing interest in scientific studies evaluating the efficacy and safety of using dietary supplements containing silicon. Its use aims at increasing blood levels of this element and improving the skin and its annexes appearance. There are different forms of silicon supplements available and the most important consideration to be made in order to select the best option is related to safety and bioavailability. Silicon supplements are widely used, though there is wide variation in silicon bioavailability, ranging from values below 1% up to values close to 50%, depending on the chemical form. Therefore, the aim of this study was to evaluate the scientific literature related to the different chemical forms of silicon supplements available and the limitations and recent progress in this field. According to reported studies, among the different chemical forms available, the orthosilicic acid (OSA) presents the higher bioavailability, whereas the others forms have absorption inversely proportional to the degree of polymerization. However, clinical studies evaluating safety and efficacy are still lacking.

Keywords: Biological availability, Collagen, Dietary supplements, Hair, Silicon, Silicon compounds, Skin aging

INTRODUCTION

Silicon is the second most abundant element on earth, exceeded only by oxygen. Also, it is the third most abundant trace element in the human body., It is present in the water and in plant and animal sources. On the skin, it is suggested that silicon is important for optimal synthesis of collagen and for activating the hydroxylation enzymes, improving skin strength and elasticity. It was shown that physiological concentrations of orthosilicic acid (OSA) stimulate fibroblasts to secrete collagen type I. In the case of hair, it is suggested that higher silicon content in the hair fiber results in a lower rate of hair loss and increased brightness. Nails are also affected by the presence of silicon, since this is the predominant mineral in their composition., For these beneficial effects, there is growing interest in scientific studies to examine the efficacy and safety of the use of dietary supplements containing silicon, which aims to increase serum levels of this element and hence lead to improvements in the skin and its annexes. There are different forms of silicon supplements available and to select the most suitable option, the most important considerations to be made are regarding safety and bioavailability. In some countries, these supplements are already widely used, although there is great variation in silicon bioavailability, ranging from less than 1% up to values close to 50%, depending on the chemical form.,

However, it is observed that there is still no consensus among researchers about the statement that silicon is an essential element for man or about the real benefits obtained from the use of supplements containing silicon. Thus, it is extremely important to critically evaluate the information published so far regarding efficacy, safety and bioavailability of silicon used in complementary supplements to the diet. That was the aim of this study.

SKIN AGING PROCESS

The aging process occurs by two main mechanisms: intrinsic and extrinsic. The intrinsic aging is unavoidable and results in atrophy, fibroblasts reduction and thinning of blood vessels. The collagen fibers are particularly affected in this process, which results from the accumulation of irreversible degenerative changes associated with aging.,, The extrinsic aging primarily results from damage caused by ultraviolet radiation. Other factors related to this type of aging include smoking, pollution and inadequate nutrition. These types of injury lead to increased degradation of collagen and elastin. Also, a reduction in the number of extracellular matrix proteins and a decrease in fibroblasts are described,, in addition to a reduction of silicon levels and hyaluronic acid in the connective tissues.

Collagen and fibers formed by it are responsible for the biomechanical properties of the skin, allowing it to act as an organ of protection from external trauma. They present as essential components of structural integrity of the connective tissue and are present in large quantities in the skin, bones and joints., A reduction in the amount of collagen in the skin of about 1% per year after 21 years of age is described, resulting in thickness reduction and elasticity loss, which is directly related to the wrinkles depth.,

Changes occurring after menopause are even more striking, including loss of about 30% of skin collagen in the first 5 years and annual loss of 0.55% of elastin., The biosynthesis process of collagen after the third or fourth decade of life remains at a low level, insufficient to allow mature skin to repair or replace the collagen that has been lost as part of the degradation processes associated with age. The decrease of collagen that occurs after menopause especially correlates with decreased bone mineral density associated with age.

By the study of skin aging process, it’s possible to observe that the degradation of collagen fibers has a remarkable role in this context. Based on this, the use of mechanisms that influence the biosynthesis of this protein is as a potential tool for improving and preventing skin aging.

SILICON: A UBIQUITOUS ELEMENT

Considering the abundance of silicon in the human body, it seems unlikely that its deficiency occurs in men and women.

In 1972, two studies by two different research groups showed that silicon was an essential element in chickens and mice., These experiments demonstrated that nutritional deficiencies of silicon led to skeletal deformities such as abnormal skull and long bone structures, as well as malformed joints with cartilage poor content. Thus, an important role of silicon in bone mineralization was demonstrated.

After that, several studies showed silicon participation in different mechanisms, with positive results associated with higher concentrations of this element in the blood in patients with osteoporosis, atherosclerosis, skin aging and fragile hair and nails., However, there are no conclusive data to determine whether or not silicon is an essential nutrient for humans and superior animals, since its deficiency has not led to cell cycle interruption in mammals, and its functional role remains to be clearly defined., Most of the silicon present in the blood is filtered by the kidneys, suggesting that this mechanism represent the major route of excretion and that levels of silicon in blood correlate with the levels present in urine. For this reason, various studies evaluate the serum concentration as well as the one present in urine in order to study the bioavailability of silicon and its derivatives.

Silicon occurs naturally in foods in the form of silicon oxide and silicates, which are present in water and in plant and animal sources and are found in high concentrations especially in cereals., The main sources of silicon from the diet in the Western Hemisphere are cereals (30%), followed by fruit, beverage and vegetable-derived products in general. Together, these foods provide about 75% of the total silicon ingested by man.

However, there are studies that question the bioavailability of silicon from some sources, due to the low solubility of some compounds, especially those that are polymerized., Thus, although significant quantities of silicon are present in some foods, sometimes it is presented in an insoluble form and cannot be directly absorbed in the gastrointestinal tract. The silicon present in food is solubilized in the acid environment of stomach, becoming OSA [Si (OH)4], which can then be absorbed. It is described in the literature that the aging process is associated with an increase in gastric pH, which decreases the conversion capacity of this silicon found in foods in the bioavailable form.

OSA is the main type derived from silicon present in drinking water and other liquids, including beer, and it is considered the most readily available form of silicon to humans. It is stable when diluted (<10-4 M) but polymerizes in higher concentrations in a pH close to neutral. Absorption studies indicated that only OSA is available while its polymerized form is not absorbed. Questions on the bioavailability of silicon from the mineral water are reported in the literature. In a study conducted with rats that received supplementation with OSA in the water they ingested, there were no significant differences in the concentration of silicon present in bones in relation to baseline. In beer, it demonstrated that about 80% of the total silicon found corresponds to OSA. However, there are discussions involving the availability of OSA, which could be unstable in industrial processes such as, for example, bottling.

At high concentrations, OSA needs to be stabilized so it doesn’t polymerize excessively, resulting in a reduced bioavailability. For this reason, silicon-containing supplements attempt, by different methods, to concentrate OSA and stabilize it in a way to make it more bioavailable.

FOOD SUPPLEMENTS CONTAINING SILICON

Different consumptions patterns of supplements containing silicon are observed around the world. As an example, the organic silicon – commonly the monomethyl silanetriol (MMST) – is more consumed in France, while in Germany the colloidal silicon are more present and, in Belgium, choline-stabilized OSA (ch-OSA) is more frequent.,

The MMST is not only organic, but also monomeric while other silicates show different degrees of polymerization, which should explain the different silicon absorption values in experiments with rats and in some preliminary studies in humans., Some studies have shown that it is readily absorbed after digestion and observed no adverse events with its use. Nevertheless, it is noteworthy that, until the completion of these works, specific studies to evaluate its safety were not conducted.

Jugdaohsingh et al, in 2013, conducted a study to assess the safety of using this supplement. A group of 22 healthy women, who were not menopausal, received MMST oral supplementation for 4 weeks, with the maximum recommended dose of 10.5 mg/Si/day. The authors concluded that MMST intake is safe and that it was absorbed. They also presented data to prove that, after ingestion, there is conversion of MMSR in OSA, which would justify its absorption.

However, in response to the published article, Vanden Berghe questioned some points of the study, claiming that studies of longer duration in humans and toxicological tests in vitro and in animals are needed in order to prove the safety of using the supplement containing MMST. According to Vanden Berghe, these studies were not presented in the article in question and they are also scarce in the available literature on the subject. The statement on MMST conversion in OSA was also questioned.

The authors of the original study published a response that kept emphasizing the study’s findings. They argued that they used rigorous methodology and that, in the adopted conditions, they could conclude it was safe to use the supplement containing MMST. The authors, however, agreed that studies with larger numbers of volunteers and greater length of time would be needed for the continuation of research involving this supplement.

MMST has been used as a silicon source for a long time around the world, especially in Europe. This supplement, unlike others available, does not contain nano-silica particles, on which concerns regarding the safety have been reported., However, the European Food Safety Authority (EFSA) considers that there is not enough data to justify the use of MMST as silicon supplement.

The greatest number of studies in the literature evaluates ch-OSA. The ch-OSA has been approved for human consumption and is known to be non-toxic, in addition to representing the most bioavailable form of silicon.,

In chemical terms, ch-OSA is a mixture of OSA and choline chloride. Given the lack of data about adverse reactions to silicon, a recommended dose has not been established. Nevertheless, according to the American regulatory agency, choline, silicon oxides and various silicates are classified as substances “generally recognized as safe”.,

The stabilization with choline is considered the most advanced technology for OSA stabilization. Choline has important characteristics that place it in the position of an ideal stabilizer for OSA, in addition to promoting benefits due to its own characteristics. In high concentrations, choline avoids extensive polymerization and aggregation of silicon particles, to keep it in an aqueous suspension.

Furthermore, as previously mentioned, choline present in the compound may have a synergistic effect with OSA, since it is well known its participation in many basic biological processes. Choline is a precursor of phospholipids, which are essential for the formation of cell membranes, as well as being involved in processes such as cell signaling, lipid metabolism and protection against the collagen breakdown mediated by homocysteine.,

In 2009, EFSA requested a scientific opinion to the Panel on Food Additives and Nutrient Sources Added to Food concerning ch-OSA safety. The only objective was to evaluate ch-OSA as a silicon source and also its bioavailability. Thus, silicon safety itself, in terms of daily amounts that can be consumed and its classification as a nutrient, was outside the scope of scientific opinion published by the Panel.

Based on different studies conducted in animals and in humans, the Panel concluded that the silicon present in ch-OSA is bioavailable and that its use in supplements, in the proposed doses, does not present risks for safety, providing that the choline maximum level is not exceeded (3.5 g/day).

Studies were analyzed both in animals and in humans so the conclusion on bioavailability and safety were published by EFSA. A study of calves that received supplement containing ch-OSA or placebo for 23 weeks evaluated the evolution of serum silicon concentration. There was a 4.9% increase at this concentration in the group of animals receiving silicon. In another study, Vanden Berghe assessed the bioavailability of silicon in offspring of 21 pigs, which received or not (control) supplement containing ch-OSA during the gestation (16 weeks) and lactation (four weeks) period. In the offspring of pigs that received supplement containing silicon, significantly higher silicon concentrations were found (150% increase) than in the offspring of the control group. The authors attributed this result to the bioavailability of silicon in the supplement containing ch-OSA and also to the maternal transfer capability of absorbed silicon. The silicon absorption from supplement containing ch-OSA was assessed in a study of 14 healthy volunteers aged 22-34 years. Each volunteer received successive oral doses of silicon from different sources. A significant increase in serum concentration of silica compared to baseline was observed for ch-OSA., This study demonstrated that the bioavailability of silicon is to a great extent dependent on the chemical form of the compound.

In another study, conducted in order to examine in vivo absorption of silicon by evaluating its serum dosage and its urinary excretion, different patterns of absorption for the different sources used were found. This study obtained different results, depending on the source, although it has evaluated absorption in just a healthy volunteer. It was observed that a diet rich in silicon does not result in sufficient bioavailable amounts of this element that would lead to a statistically significant increase in its urinary excretion and serum levels, when compared with the period in which the volunteer was subjected to a normal diet. A significant increase in silicon urinary excretion was observed when the evaluated supplementation consisted of tablets containing dry extract of horsetail. However, the silicon serum levels remained constant. Only the biologically active silicon present in solution at 2% silicon in a matrix of choline and glycerol was absorbed, which reflected in the significant increase of silicon in both serum levels and in urine excretion. Based on this study, the authors concluded that silicon absorption is strongly influenced by its chemical form and matrix.

Sripanyakorn et al measured silicon uptake from 8 different sources. In healthy volunteers, blood and urine samples were analyzed to quantify the concentration of silicon. The results confirmed that the degree of silicon polymerization is inversely proportional to intestinal absorption.

SILICON AND ITS RELATION WITH SKIN, HAIR AND NAILS

Regarding the skin, it is suggested that silicon is important for optimal synthesis of collagen and for activating the hydroxylation enzymes, important in the formation of collagen network, improving skin strength and elasticity. Silicon is also associated with the synthesis of glycosaminoglycans. Concerning the hair, it is suggested that strands with higher silicon content tend to have lower falling rate and higher brightness. Nails are also affected by the presence of silicon, since this element is one of the predominant mineral in their composition. The presence of soft and brittle nails can indicate systemic deficiency of silicon. By improving the quality of nails, there is an increased protection against nail infections.,

In a study with 50 healthy volunteers, aged between 40 and 65 years and with clear clinical signs of facial photoaging, the effect of the intake of supplements containing ch-OSA to the skin, hair and nails were analyzed. The supplement was held for a period of 20 weeks, with 2 capsules containing 10 mg of ch-OSA taken daily. Also, serum concentrations of various components in the blood were evaluated in order to verify safety of oral treatment. The silicon intake under these experimental conditions was considered safe, since there were no reported adverse events with this treatment. This study, according to the authors, was the first randomized, double-blind, placebo-controlled trial that showed positive results in the skin microtopography and anisotropy after the intake of supplement containing ch-OSA. At the end of the period of use supplement containing silicon, there was a significant improvement in the skin surface characteristics and in its mechanical properties.

Also in this study, it was observed a significant improvement in the fragility of nails and hair in the group using the ch-OSA. The placebo did not lead to significant differences in rating assigned by the volunteers by the self-assessment questionnaires completed before the start and after the end of the study.

Another randomized study with 48 volunteers investigated the effect of ch-OSA on hair. The volunteers had thin hairs and were divided into 2 groups: ch-OSA and placebo. The first group received daily doses of 10 mg of silicon, for a period of 9 months. Morphology and mechanical properties of hair were evaluated at the beginning and at the end of the study. In general, positive results were obtained in the evaluated hair properties, such as strand resistance to breaking, for example. Furthermore, the area of the strand front section increased significantly after 9 months of supplementation containing ch-OSA, whereas the placebo group exhibited no significant difference.

The fact that ch-OSA have partially prevented the loss of hair tensile strength suggests that it has a structural effect on hair fibers. According to the authors, an interaction with keratin is possible, considering that OSA is the chemical form of silicon prevalent in physiological fluids and that silanol group, present on OSA, is known to form complexes with amino acids and peptides.,,

CONCLUSION

The analysis of the scientific literature on the use of supplements containing silicon shows great therapeutic potential of this element, as it operates in different conditions of human health and presents aesthetic properties. Among the various chemical forms available, the analysis of studies shows that OSA is the form that presents greater bioavailability; other forms have absorption inversely proportional to the degree of polymerization. We also observed that ch-OSA is the most referenced form in the literature, suggesting a greater scientific support regarding its use. However, there are few studies evaluating the safety, efficacy and bioavailability of the different existing chemical forms of silicon that use proper design, large number of volunteers and long follow-up period.

Does Biotin Really Help With Hair Growth? (What Studies Show)

Let’s talk biotin and hair growth. You know those commercials that claim that these hair, skin and nail multivitamins can help speed up hair growth, and add volume at the same time? Well it’s the vitamin biotin in these products that claims to be the vitamin for beauty. It’s hard to avoid a conversation on hair growth without hearing about biotin, so I have dug into the scientific studies to determine if biotin truly does help to promote hair growth or not.

Let’s find out if taking biotin really makes a difference, and uncover the sources, and health benefits of this “beauty” vitamin.

What is Biotin?

what is biotinBiotin is often referred to as Vitamin H, for hair or B7. Biotin is a water soluble b-vitamin. This vitamin is a vital part of a healthy metabolism and is essential for creating important enzymes. (1) Since Biotin is classified as a b-vitamin it is an excellent source of energy, and is used as energy in our bodies. This vitamin is known to help many systems in the body including our skin, nerves, digestive tract, metabolism, and our cells. Biotin may play an important role in many parts of the body, but we need to take a closer look as to whether or not it really does speed up hair growth. First let’s take a look at the sources of Biotin.

Sources of Biotin

Although biotin is supplemented with more times than not when trying to promote hair growth, biotin can also be found in small amounts in foods. At the end of the day getting biotin fromfood sources it better absorbed in the body than from a supplemental version of the vitamin. Sherry Ross, OB/GYN and Women’s Health Expert at Providence Saint John’s Health Center in Santa Monica states that the foods listed below contain small amounts of Biotin.

sources of biotin

  • Cauliflower
  • Liver
  • Salmon
  • Carrots
  • Bananas
  • Soy flour
  • Yeast
  • Wheat germ
  • Eggs
  • Dairy products
  • Nuts
  • Swiss chard
  • Chicken

Health Benefits of Biotin for Your Hair

benefits of biotin“Many people take biotin supplements to increase the health of their skin, hair and nails. While more research is needed, it seems that B7 may be helpful in these areas.”

Taking biotin for hair growth can be promising, and there have been studies to prove how effective it is:

  • Ablon Skin Institute Research Center and the University of California, concluded that women who suffered with thinning hair had great success with hair growth when taking biotin.
  • Registered Dietitian, Lauren Graf who works out of a cardiac wellness center has stated that biotin is very important for hair, skin and nails, and that those with low levels could experience thinning hair, and brittle nails.
Biotin for Thinning Hair

We known that biotin can benefit our hair, but let’s talk about how exactly it can prevent and improve hair thinning.

Hair thinning can occur for a number of reasons such as aging, or certain medications however it can also occur if someone is not getting enough biotin. Supplementing with biotin can improve hair thinning, and actually prevent it from happening.If you are getting adequate amounts of biotin your chances of developing a deficiency are lower which means your chances of thinning hair reduces as well!

Biotin for Hair Growth

This is what most of us want to know before taking biotin. Will biotin really work to help promote hair growth?

Biotin is vital to cell proliferation, which is why it is a valuable tool in hair growth.” (3)

When it comes down to what hair is composed of, it actually consists of keratin which is a protein. This is a big reason as to why biotin helps to promote hair growth. When biotin is ingested, biotin then reacts with cell enzymes and plays a large part in producing amino acids. Amino acids are the building block of proteins. Strings of amino acids are what makes up a protein. Since hair consists of protein, consuming foods high in biotin can actually boost hair growth, and lead to healthier hair.

What Biotin Won’t do for Your Hair

While biotin can be very beneficial for hair growth, supplementing with biotin will not help to prevent hair loss. Oregon State University’s Linus Pauling Institute states that there is just not enough scientific evidence to prove that biotin supplementation can improve hair loss. It’s important to understand why you are experiencing hair loss in the first place, it may be something that needs to be addressed a different way before trying to supplement with biotin. For example someone with a hormonal imbalance that is experiencing hair loss is not going to see hair re-growth from biotin until they address their hormonal imbalance, the root cause of their hair loss.

How Do You Know if You Are Deficient in Biotin?

biotin defiiciencyBiotin deficiency is actually quite rare in the US, however if you are not getting enough biotin you will see noticeable symptoms.

One of the obvious symptoms of biotin deficiency is thinning hair, and weak or brittle nails. A biotin deficiency can however present itself in more ways than one.

Other deficiency symptoms include nausea, muscle pain, fatigue, loss of appetite, depression and skin changes.

Proper Dosage of Biotin

The Mayo Clinic’s dosage recommendation for adults is between 30-100 mcg per day of biotin. (2) While The Institute of Medicine’s Food and Nutrition Board recommends that  adults should get 19.30 mcg of biotin per day. The dosages ranges according to your age, and if you are actually biotin deficient or not.

Should You Supplement With Biotin?

supplementThe bottom line is that if you have thinning hair, brittle nails and skin issues then you may benefit from taking biotin. If you are deficient in biotin then supplementing can also not only be very important for your overall health, but can also be beneficial for hair growth. Even though supplementing with biotin can give your hair and nails a nice boost, a vitamin alone should never replace a healthy diet high in vitamins and minerals. If you eat well, and eat foods high in biotin while always staying hydrated then you will not have to worry about biotin deficiency. It’s important to remember that ” Your body needs other substances found in food, such as protein, minerals, carbohydrates and fat. Vitamins themselves cannot work without the presence of other foods.” (4) If you are consuming healthy foods, as well as foods high in biotin, and you are just looking to boost your hair growth then taking a biotin supplement will help your hair grow faster.

“Healthy hair comes from a healthy diet, and a healthy lifestyle. Supplementing with biotin should come second to improving your diet.”

Eclipta Alba aka Bhringaraj Extract Grows Hair Quicker than Minoxidil

Eclipta alba (also known “Bhringraj” and “False Daisy”) is a tropical herb that has been used to treat various illnesses. A traditional use for it in Ayurvedic medicine has been hair loss treatment and hair dyeing.

While many traditional remedies have not been scientifically studied, Eclipta alba has not one but two actual studies behind it showing hair growth promoting activity in rodents. In the first paper, petroleum ether and ethanol extracts of the herb were compared against minoxidil (link). The second paper also used minoxidil as a positive control, but this time the extract was made with methanol (link).

To get an overview of how effective Eclipta alba really is for growing hair, in this post we’ll be comparing the results from both papers.

The three Eclipta alba extracts

In the first paper, 500 grams of dried coarse powder of Eclipta alba was initially extracted with petroleum ether. The resulting marc was further extracted with ethanol to make the ethanol extract. These extracts were then incorporated into an ointment base in concentrations of 2% and 5% (i.e. the resulting ointments contained 2-5% ethanol extract).

In the second paper, 1 kilogram of Eclipta alba was extracted with 95% methanol and then filtered and concentrated. The final formulations contained either 3.2 mg/kg or 1.6 mg/kg of the extract in a solution of propylene glycol and DMSO.

Study design

The petroleum ether & ethanol study used six groups of rats with their backs shaved. Group I was applied ointment base only and served as control, Group II was applied 2% ethanol extract, Group III was applied 5% ethanol extract, Group IV was applied 2% petroleum ether extract, Group V was applied 5% petroleum ether extract, and group VI was applied 2% minoxidil and acted as positive control. The ointments were applied for 30 days.

In the methanol study, mice with hair already in telogen phase were selected. Two experiments were done: the first one compared the effectiveness of 1% and 2% minoxidil to a control vehicle, and the second one looked at the effectiveness of 1.6 mg/kg and 3.2 mg/kg methanol extracts of Eclipta alba. The extracts were applied for 10 days.

Results from Eclipta alba in rats

Shaved rats treated with the petroleum ether extract of Eclipta alba began growing new hair significantly faster than rats in the control group. Whereas the control rats took 12 days to initiate hair growth, the petroleum ether extract rats took only 5 to 6 days, with the stronger ointment being slightly more effective. The time it took to completely cover the shaved area in hair was also decreased from 24 days to 20 days.

2% minoxidil reduced hair growth initiation time to 6 days and completion time to 20 days. Therefore, minoxidil was as effective as 2% petroleum ether extract but slightly less effective than 5% petroleum ether extract. Ethanolic extracts reduced the time of hair growth initiation only slightly and had no effect on completion time.

The hair growth effects were due to a marked conversion of hair follicles from telogen to anagen phase. In the control group and ethanol extract group, most of the follicles were in telogenic phase, while in the minoxidil and petroleum ether extract groups most follicles were in anagenic phase. Notably, petroleum ether extract of Eclipta alba was even more effective in inducing anagen phase than minoxidil.

Petroleum ether extract also increased the length of the hair follicles, similarly to minoxidil. In the control group only 34% of follicles were longer than 0.5 mm. In the extract and minoxidil treated groups the percentage was 44-49%, with minoxidil being most effective. Once again, ethanol extract did not have a significant effect.

Results from Eclipta alba in mice

Conversion from telogen to anagen phase was observed in 87.5% of the mice treated with the stronger methanol extract (3.2 mg/kg) and in 50% of the rats treated with the weaker extract (1.6 mg/kg). This was evidenced by the increased number of follicles in the subcutis layer and a thickening of the skin. The total number of follicles was also increased. None of the control rats showed a similar effect.

Both concentrations of minoxidil increased skin thickness, follicle count and the percentage of follicles in anagen phase. 2% minoxidil was slightly more effective than 1% minoxidil. According to the authors, the effects of minoxidil and the methanol extracts were “comparable”, but looking at the data, it seems that the stronger extract of Eclipta alba was in fact significantly more effective. For example, 2% minoxidil increased mean follicle count from 43 to 73, whereas the 3.2 mg/kg methanol extract increased it from 19 to 66. The conversion from telogen to anagen was also more pronounced in the methanol extract group.

Conclusion

A petroleum ether extract of Eclipta alba increases hair growth in rats by converting follicles from telogen to anagen phase. The hair growth promoting effect is similar to that of minoxidil. An ethanol extract, however, showed only very modest results. No change in fur color was reported.

In mice, methanol extracts of Eclipta alba induce conversion of hair follicles from telogen to anagen phase. Eclipta alba also increases skin thickness and the number of total and subcutaneous hair follicles. These effects are even more pronounced than those seen from 1% and 2% minoxidil. Since the mice had black fur to begin with, the hair dyeing claims could not be evaluated.

Possible reasons for the lack of efficacy in ethanol extracts of Eclipta alba are the lack of wedelolactone and beta-sitosterol. While petroleum ether extracts and methanol extracts contain significant amounts of wedelolactone, ethanol extracts do not. Wedelolactone has the abilitiy to suppress caspase-11 (link) and androgen receptors expression (link).

Petroleum ether extracts are also high in beta-sitosterol, which has been shown to inhibit 5-alpha-reductase (link), a key factor in genetic hair loss. The beta-sitosterol content of methanol extracts of Eclipta alba was not reported in the study.

Hair can be considered a crowning glory for many women and a sign of youth and vitality for men. When men and women begin to lose their hair, this can become a source of insecurity. In addition to products like Rogaine or other prescription medications, there are many natural remedies, like eating pumpkin seeds, that may help grow hair.

Pumpkin seeds contain fatty oils with linoleic acid and oleic acid, both known to prevent cancer-causing cell production. They are also an excellent source of vitamins A, B6 and C. In addition, the seeds contain beneficial nutrients like zinc, magnesium, calcium and iron. Perhaps most important to those suffering from hair loss, the seeds contain cucurbitin, a unique amino that may be responsible for pumpkin seeds’ effects on hair growth.

There are many causes of hair loss, including poor health or long-term illness, genetics, stress and hormonal imbalance. A lack of important nutrients in your diet can also lead to hair loss or a nonproductive scalp. The oil from pumpkin seeds are believed to effect testosterone and androgen levels in the body. Lack of androgens in the body is believed to be a primary cause of hair loss. Eating a handful of seeds a day can benefit in the fight for hair growth.

https://www.leaf.tv/articles/pumpkin-seeds-and-hair-growth/

Pumpkin Seeds for Prostate Problems and Preventing Hair Loss

Raw pumpkin seeds are a high protein and mineral rich food that have some specific benefits for hair loss prevention and protecting men against prostate problems.

Here’s just what makes pumpkin seeds so good for both preventing hair loss and improving your prostate health if you are a man.

BHP, Dihydrotestosterone and Pumpkin Seeds 

Benign prostatic hyperplasia, commonly called BPH, is a painful male condition that leads to constriction of the urethra and difficulty urinating.

It is quite common in older men but there are several health nutrients in pumpkin seeds that can help by reducing dihydrotestosterone, the primary cause of BHP.

Delta-7-Sterine

The first of these is a mild steroidal compound called delta-7-sterine. Research has found delta-7-sterine directly competes with the much more potent dihydrotestosterone (DHT) at the receptor sites in the prostate.

DHT is strongly implicated in prostate cell proliferation, but when delta-7-sterine is present in the diet in large enough amounts, it appears to minimize the harmful effects of dihydrotestosterone on the prostate.

Beta-Sitosterol

Pumpkin seeds contain high levels of phytosterols, including the much studied beta-sitosterol. Beta-sitosterol has been shown to block the conversion of testosterone to dihydrotestosterone by inhibiting the enzyme 5-alpha-reductase.

This can have many positive effects, like a reduction in hair loss, but specifically for prostate problems, the less excess DHT in the body to act upon the prostate the better.

In a double-blind placebo-controlled study of treating benign prostatic hyperplasia with phytosterols, BPH symptoms were shown to be ‘significantly improved in the treatment group’ with no side effects noted.

Zinc

The high zinc content in pumpkin seeds is another reason why they are considered so good for guarding against prostate problems.

Zinc is important for proper hormone production, including testosterone. It also has antioxidant and anti-inflammatory properties and is said to enhance your immune response. All of these are potentially beneficial for a man suffering from an enlarged prostate.

Zinc is also needed for healthy hair and a deficiency in this mineral is often associated with hair loss as it directly affects the proper functioning of your hair follicles.

Other Nutrition for a Healthy Prostate in Pumpkin Seeds

Pumpkin seeds also contain other protective factors to help prevent or treat prostate problems, such as good levels of antioxidant carotenoids like beta-carotene, magnesium and essential fatty acids.

The incidence of male prostate problems has been found to be considerably lower in countries where pumpkin seeds are often consumed, like Austria and Hungary.

This is hardly surprising with all of the different nutrients in pumpkin seeds and eating them regularly may help moderate dihydrotestosterone levels, reduce an enlarged prostate and relieve the symptoms of benign prostatic hyperplasia.

Pumpkin Seeds and Hair Loss

Excessive dihydrotestosterone can cause many problems for men, particularly later in life. The same DHT responsible for enlarging the prostate and causing benign prostatic hyperplasia, also contributes to hair loss and eventually male pattern baldness.

DHT causes hair loss in men by shortening the anagen (growth) phase of the hair follicle. This can lead to progressively finer and weaker hairs that, over time, simply stop growing.

However, the beta-sitosterol in pumpkin seeds has been shown to act as an inhibitor of the enzyme 5-alpha-reductase. It’s this enzyme that converts testosterone to hair damaging dihydrotestosterone.

http://superfoodprofiles.com/pumpkin seeds-prostate problems%20preventing-hair-loss

 

. 2015 Jul-Sep; 7(3): 225–236.
PMCID: PMC4471648

Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds

Abstract

Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment.

Keywords: Clinical pharmacokinetics, clinical studies, herbal hepatotoxicity, Polygonum multiflorumThunb., therapeutic assessment

INTRODUCTION

Plants, herbs, and ethnobotanicals have been selected and used empirically as drugs for centuries, initially as traditional preparations then as pure active principles, with the knowledge and accumulated practice passing from generation to generation.[,] Medicinal plants are plants containing the substance that are used for therapeutic purposes or which are precursors for the synthesis of useful drugs.[] Herbal Medicinal can be categorized into two broad parts. The first one includes complex of mixture containing a wide variety of compounds (e.g.: Infusions, essential oils, tinctures or extracts), and the second category refers them as pure, chemically define active principles.[]

Polygonum multiflorum Thunb. (PMT, Polygonaceae family, Figure 1)), well known as He shou wu in China and Fo-ti in North America,[] is one of the most popular perennial Chinese traditional medicinal vine-like herbs, officially listed in the Chinese Pharmacopoeia.[] Various parts of the plants were utilized for different medicinal purposes. The leaves [Figure 2a], root tuber [Figure 2b] and rhizomes [Figure 2c] of this plant have been used as tonic and anti-aging agents[,,,,,] whereas the stem [Figure 2d] is used to alleviate insomnia and even to have an antidiabetic therapeutic activity as well.[,,]

Figure 1

Polygonum multiflorum Thunb

Figure 2

Photos of (a) leaves, (b) tuber roots, (c) underground rhizomes and (d) stem from Polygonum multiflorum Thunb

Laboratory studies and clinical practice have demonstrated that PMT possesses various biological and therapeutic actions, including anti-tumor,[,] antibacterial,[] anti-inflammatory,[] anti-oxidant,[,,] anti-HIV,[] liver protection,[,] nephroprotection,[] antidiabetic,[,] anti-alopecia,[,] and anti-atherosclerotic activities.[,] It has been also reported to exert preventive activity against neurodegenerative diseases,[,,,,] cardiovascular diseases and to reduce hyperlipidemia as well.[,]

The clinical efficacy, as well as the safety of PMT and its bioactive products, has attracted much attention in the recent years; due to the increasing reports of various cases on hepatotoxicity,[,,,,] published worldwide. In the present review, the advancements in thorough investigation of clinical studies and pharmacokinetics (PKs)-pharmacodynamics (PDs) profile of P. multiflorum are discussed, meanwhile describing the clinical features of this particular herbal-induced liver injury. This report will enlighten the broad understanding on the clinical therapeutic evaluation of PMT or other herbal drug containing quite the same phytochemical components.

METHODOLOGY

An electronic search was performed by searching several databases: PubMed (Medline), Highwire, HerbMed, Google Scholar, Scopus, Cochrane Database of Systematic Reviews and Cochrane Library using key terms including, “PMT,” “He shou wu,” “Shou-Wu-Pian,” “Shen-Min,” “Fo-Ti,” and “clinical study,” “humans,” “patients,” “case report,” “hepatotoxicity” to identify English-language publications (case reports, case series, prospective study and clinical review articles) and abstracts published regarding P. multiflorum and/or its compounds. Furthermore, we scanned the references lists of the primary articles to identify the publications not retrieved by electronic research. A total of 54 publications were identified, and the results compiled. They showed 7 articles relevant to clinical PKs-PDs analysis, 2 to anti-inflammatory effect, 2 for dyslipidemia treatment, 2 relevant to sleep disorders, 3 for neurodegenerative diseases and 52 patients with hepatotoxicity due to P. multiflorum ingestion. The quality of clinical studies on P. multiflorum, the characteristics and outcomes of patients reported with herbal hepatotoxicity and the P. multiflorum claimed pharmaco-therapeutic values are reviewed and discussed in this paper.

CLINICAL PHARMACOKINETICS AND PHARMACODYNAMICS STUDIES OF POLYGONUM MULTIFLORUM EXTRACTS AND/OR ITS BIOACTIVE COMPONENTS

Herbal medicines are mixtures of more than one active ingredient. The multitude of pharmacologically active compounds obviously increases the likelihood of interactions taking place. Hence, the likelihood of herb-drug interactions is theoretically higher than that of drug-drug interactions, if only because synthetic drugs usually contain single chemical entities.[] Case reports and clinical studies have highlighted the existence of a number of clinically important interactions, although cause-and-effect relationships have not always been established. Herbs and drugs may interact either pharmacokinetically or pharmacodynamically [Figure 3].[]

Figure 3

Schematic representation of the physiologic processes determining drug disposition in the human body and the relationship of pharmacokinetics and pharmacodynamics to these processes (A: Administration, D: Distribution, M: Metabolism, E: Excretion)

To date, a number of in vitro studies have addressed the potential of selected herbal extracts and/or specific constituents to inhibit or induce drug-metabolizing enzymes or transporters, especially cytochrome P450 (CYP450) isoforms and P-glycoprotein (P-pg). However, translation of in vitro data in a clinical setting is hard to accomplish, and discrepancies are often observed between predicted outcomes on the basis of the in vitro studies and results of controlled clinical studies.[]

Several pharmacological and clinical studies have been done to investigate the PK-PD parameters analyzes of PMT and/or its bioactive components. In 2002, some Korean scientists conducted a clinical PK study about rhein; one of the main bioactive of PMT.[] This research produced some interesting findings, enlightening that in terms of the bioavailability, while the levels in aloe-emodin, emodin, and chrysophanol [Figure 4] in herbal extracts were much higher than rhein level, only rhein was selectively absorbed by the body even if rhein is structurally similar to other anthraquinones.[] These findings corroborate the results of another clinical study published a decade earlier by Krumbiegel and Hu.[] This phenomenon can be explained by one of the three following possibilities. The first one is that rhein are formed when sennosides (e.g.: Sennoside A, Figure 5) are decomposed by bacteria in the intestines,[] but the time courses of plasma rhein concentrations render this possibility highly improbable. The second possibility is that sennosides are metabolized by intestinal bacteria into anthrones [Figure 6], and the sulfoconjugation or glucoronidation occurs leading to the excretion of the substance through urine.[] The third possibility stressed out the fact that rhein can be easily bio-transformed from aloe-emodin.[,] Furthermore, in another clinical investigation, the high bioavailability of rhein was assessed using the routes of administration as comparative key of the research. The findings suggested that after a single dose of herbal extract, the oral bioavailability of rhein was significantly higher than its rectal bioavailability.[] By analysis of the route administration, the absorption of weak acids such as rhein may be optimal in the acidic environment of the stomach, whereas their absorption might be unfavorable in the relatively alkaline situation of the small intestine. Retention enema therapy requires multiple, higher daily doses due to poor bioavailability if the same plasma rhein concentration as oral therapy is to be achieved.[]

Figure 4

Chemical structures of aloe-emodin, chrysophanol, danthron, emodin, physcion and rhein

Figure 5

Chemical structure of sennoside A

Figure 6

Chemical structure of anthrones

Herbal medicines constituents may affect the function of the drug-metabolizing enzymes by inhibiting through different, yet not completely disclosed mechanisms, the catalytic activity of specific enzymes, or they may simply compete for binding. In either case, increase in oral bioavailability and/or reduction of hepatic clearance of the affected drugs are expected to occur, thus leading to an increase in the plasma drug levels, which may expose the patient to a serious risk of adverse drug toxicity.[] The drug transporters and drug-metabolizing enzymes involved in the in vivo process, the modulatory effects on both P-pg[,,] and CYP450 isoenzymes[,] and the acute toxicity[,,,,,] of PMT and/or its major bioactive compounds are all well documented. P-gp-based drug interactions are a major concern in the clinic and in preclinical drug development, especially with respect to the intestinal absorption of drugs and distribution of drugs across the liver, kidney, intestine and blood-brain barrier.[] Despite the widespread use of herbal medicines, documented herb-drug interactions are spare. However, studies on common herbs indicate that significant herb-drug interactions exists.[] Several commonly used traditional Chinese medicine (TCM) have been reported to interact with P-gp. For example, St. John’s wort was found to increase the duodenal P-gp expression by 1.4-fold in healthy volunteers after multiple oral administrations. It was also reported that St. John’s wort could result in an 18% decrease of digoxin exposure after a single oral dose of digoxin (0.5 mg).[,] Li et al. investigated the inhibitory effect of PMT constituents on P-pg mediated the digoxin transport in MDR1-MDCKII cells. The herbal constituents tested were trans-Resveratrol [Figure 7], 2,3,5,4′-tetrahydroxylstilbene-2-O-β-D-glucoside (TSG, Figure 8), emodin, chrysophanol, aloe-emodin, and physcion. Among the various constituents of P. multiflorumtested, emodin was significantly the strongest inhibitor of P-gp (IC50= 9.42 μM) in MDR1-MDCKII and Caco-2 cells.[] Furthermore, clinical study findings enlightened emodin to be found to possess the strongest promising effect for overcoming P-gp mediated steroid resistance by inhibiting the P-gp efflux function.[]

Figure 7

Chemical structure of trans-resveratrol

Figure 8

2,3,5,4’-tetrahydroxylstilbene-2-O-β-D-glucoside

Genetic polymorphisms in the CYP450 enzyme also contribute to differences in an individual’s ability to metabolize herbal medicines. The use of concurrent medications that either inhibit or induce one or more isoforms, which may result in significant changes in the rate of drug clearance, is one of the major reason for altered CYP450 activity.[,] CYP450 1A2 (CYP1A2) and CYP450 3A4 (CYP3A4) are involved in the metabolism of xenobiotic in the body,[,] their expression appear to be induced by various herbal medicines and/or dietary constituents.[] The genotype and the allelic frequencies of CYP1A2 were evaluated in Chinese patients with acute liver injury induced by P. multiflorum in order to investigate CYP1A2 allele polymorphism association with the hepatotoxicity from PMT.[] The findings revealed that the frequency of the CYP1A2 * 1C mutation in Chinese patients with P. multiflorum-induced acute liver injury differed significantly from that in healthy Chinese people, indicating that CYP1A2 * 1C is probably related to metabolism of PMT, which is, followed by acute liver injury.[] Moreover, despite the structural similarity and/or identical molecular weight of various herbal constituents, emodin significant inhibited CYP3A4/5 activity.[] Considering P. multiflorum and/or its constituents as relative toxic compound, potential drug-herb/herb-herb interactions based on CYP and P-gp should be taken into account when using this herbal medicine in the clinic. By fully appreciating the nature of PKs, PDs principles, and drug-herb interactions, healthcare professionals can drastically reduce unwanted side effects and at the same time enhance the therapeutic efficacy and usefulness of herbal medicines.

CLINICAL STUDIES DONE ON POLYGONUM MULTIFLORUM AND/OR ITS BIOACTIVE COMPOUNDS

In general, sound scientific evidence is lacking to support the use of many of the herbs currently marketed. A number of herbal products rely on anecdotal evidence to support their use. Many of the clinical trials in the literature are of limited quality owing to small sample sizes, improper randomization, and/or the lack of adequate controls. Large-scale, randomized, controlled trials have not been undertaken by the herbal industry owing to the fact that herbs are not patentable, and the potential of economic gain from positive study results is limited. A number of researchers and organizations (e.g. Cochrane collaboration) have attempted to critically evaluate available study data through systematic reviews and meta-analyses. Many of the analyses have been equivocal.[] The use of herbal medicines presents unique clinical and pharmacological challenges not encountered with conventional single-compound medicines. These medicines are usually complex mixtures of many bioactive compounds and conventional “indications and uses” criteria devised for single-compound entities may not be applicable in a significant number of ways.[]

Few clinical studies have been conducted to evaluate the traditional therapeutic claims and to study the potential of PMT and/or its various bioactive constituents, highlighting available clinical evidence.

Anti-inflammatory bioactivity

Inflammation is known to contribute to physiological and pathological processes by the activation of the immune system, local vascular system, and various cells within the damaged tissue.[] Prolonged inflammation, known as chronic inflammation, is caused by a variety of factors, including microbial pathogen infection, physical, chemical, and surgical irritation, and/or wounding and it is involved in the pathogenesis of various many chronic diseases, including inflammatory bowel diseases, rheumatoid arthritis, sepsis, and cancer.[,,,] The classical characteristics of inflammation are pain, swelling, edema, redness, and heat.[] Accumulating epidemiological, and clinical evidence shows that chronic inflammation is an important risk factor for various human diseases.[] Therefore, suppressing the production of pro-inflammatory molecules and signaling factors is one of the important target pathways in order to prevent or treat various diseases.

Various natural products from TCM have been shown to safely suppress pro-inflammatory pathways and control inflammation-associated disease. In vivo and/or in vitro studies have demonstrated that anti-inflammatory effects of PMT and/or its bioactive constituents occur by inhibition of the expression of pro-inflammatory signaling factors such as nuclear factor-κB, tumor necrosis factor-α, inducible nitric oxide synthase, cyclooxygenase-2, chemokines (e.g.,: CCL2) and cytokines (e.g.: Interleukin-1 beta).[,,,P. multiflorum was significantly tested for the treatment of the localized neurodermatitis by plum-blossom needle taping in a clinical study that enrolled 141 patients.[] Moreover, STD07 (Physcion) developed by Sun Tem Phytotech for the treatment of inflammatory bowel diseases, was evaluated in a randomized, double-blind, single-centered and placebo controlled study in Asian healthy volunteers.[] The authors found that up to 250 mg/day orally for 14 days; STD07 was general well tolerated with no clinically meaningful adverse effects in healthy volunteers in this Phase I clinical trial. Good therapeutic evidences of P. multilforum and/or its bioactive constituents have been shown in these aforementioned clinical studies to be used as anti-inflammatory agents. However, extensive clinical research is needed concerning the therapeutic value of this herbal medicine on its anti-inflammatory activity.

Dyslipidemia

The hepatocytes play important role in the distribution, biosynthesis, transferring and removal of triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL) and other related lipoproteins.[] In normal human liver, the mean contents of TC and TG are 3.9 and 19.5 mg/g wet weight, respectively. Traditionally, liver fat content >50 mg/g (5% by wet weight) is diagnostic of hepatic steatosis.[] Dyslipidemia, defined as any abnormality of serum lipids and lipoproteins, including low levels of HDL-cholesterol that is associated with increased coronary heart diseases (CHD) risk, is a substantial contributor to the incidence of CHD.[] In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle. Prolonged elevation of insulin levels can also lead to dyslipidemia. Similarly, increased levels of O-GlcNAc transferase may cause dyslipidemia. Dyslipidemia can be treated with dietary alterations and medications that affect lipid metabolism via a variety of mechanisms.[] Being the first-line therapies for reducing LDL-C serum levels, statins also have adverse effects, including muscle myopathy and derangements in hepatic function.[] Fibrates are second-line drugs that are used for the treatment of dyslipidemia and reduce serum TG levels by activating peroxisome proliferator-activated receptor alpha. However, fibrates increase serum creatinine concentrations[] and have been correlated with sudden death, pancreatitis, and venous thrombosis.[]

Traditional Chinese medicine plays a very important role in the treatment of dyslipidemic patients.[] An early uncontrolled clinical study of 50 hyperlipidemic patients suggested that PMT has lipid-lowering effect which may be related to its regulatory effect on the genes involved in cholesterol synthesis and lipoprotein metabolism.[] In a very recent randomized, double-blind, placebo-controlled clinical trial, the therapeutic effect of P. multiflorum in patients with dyslipidemia was investigated.[] The findings concluded that being a considerable composition of the multiherb formula, P. multiflorum showed marginal beneficial effect on reducing plasma LDL cholesterol levels in patients with dyslipidemia. In order to validate the claimed dyslipidemia therapeutic action of P. multiflorum and/or its bioactive compounds, further well-designed clinical studies with solid evidence are warranted to investigate this mechanism.

Sleep disorders

Insomnia or sleeplessness is a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired.[] It is prevalent in woman and the elderly by 40% more common in women than in men.[,] Different measures, such as pharmacotherapy and behavioral management, are applied for insomnia and associated complaints.[] Current insomnia pharmacotherapeutic agents mainly target the γ-aminobutyric acid (GABA) receptor, melatonin receptor, histamine receptor, orexin, and serotonin receptor. GABA receptor modulators are ordinarily used to manage insomnia, but they are known to affect sleep maintenance, including residual effects, tolerance, and dependence.[] An analysis of the United States National Health Interview Survey data from 2002 by Pearson et al.[] revealed that of the 17.4% of adults (n = 93 386) reporting insomnia or regular sleep disturbance in the preceding month, 4.5% (of that population) used complementary and alternative medicine to improve their sleep.

In an effort to discover new drugs that relieve insomnia symptoms while avoiding side effects, numerous studies focusing on the neurotransmitter GABA and herbal medicines have been conducted. Several traditional herbal medicines, such as Valeriana officinalis,[,Passiflora incarnata,[,Matricaria recutita L.,[,Humulus lupulus,[,Ginkgo bibola,[Centella asiatica,[Rhodiola rosea,[Hypericum perforatum,[Piper methysticum[,] and Zizyphus jujuba[] have been widely clinically reported to improve sleep and other mental disorders. Moreover, recently Wuling capsule, a single herb formula from mycelia of precious Xylaria nigripes was investigated for its efficacy and safety, through a multicenter, randomized, double-blind, placebo-controlled trail, in Chinese patients with insomnia.[] The clinical findings claimed that Wuling capsule could considerably improve insomnia and in terms of adverse effect, on a-6 weeks study period the drug was well-tolerated by all the patients.

In the first large-scale survey done in Taiwan of the use of Chinese herbal medicines (CHMs) or the treatment of insomnia in a Chinese population, P. multiflorum was found to be the most commonly prescribed single Chinese herb.[] Furthermore, among the Chinese herbal formulas used to treat insomnia, P. multiflorum was found significantly an important constituent of the ingredients. Although Shou-wu-teng (P. multiflorum) is often used to treat insomnia during clinical practice, no clinical research exists in the Western literature verifying its sedative or anxiolytic effects.[] Despite limited evidence from currently available studies, herbal medicines, especially P. multiflorum and/or its bioactive compounds may have beneficial effects on anxiety and insomnia in patients with bipolar disorder.[]

Anti-insomniac phytotherapy opens up an exciting aspect of research which might benefit a large number of patients suffering from different degrees of insomnia. Future research using CHM for sleep disorders requires further rigorous studies with improved methodological design, such as using an appropriate placebo control, double-blinding, validated outcome scales, and longer follow-up periods.[] There is a need for more PD and PK studies to examine the mechanism of action, dosage regimen, toxicology and adverse effects, if there are any drug interactions and the epigenetic differences affected between single active constituents versus whole extracts and complex prescriptive formulas.[,] In order to avoid location bias, as nearly all these studies are conducted in China, other countries are also encouraged further to pursue CHM clinical studies in the treatment of sleep disorders.[]

Neurodegenerative disease

Age is the leading risk factor for acute and chronic neurodegenerative diseases such as Parkinson’s disease (PD), stroke, Huntington’s disease (HD), vascular dementia (VaD) and Alzheimer’s disease (AD), etc., As population aging is occurring on a global scale, the incidence of these diseases is likely to increase significantly in the near future.[] They show common pathology of aggregation and deposition of abnormal protein. For example, deposit of Aβ and tau in AD,[] α-Synuclein for Parkinson’s disease,[] huntingtin protein in HD,[] transactive response DNA-binding protein 43 in frontotemporal dementia and amyotrophic lateral sclerosis.[] Neurodegenerative diseases usually have the symptoms of loss of orientation, spoken language, comprehension and learning abilities. To date, there is a lack of effective preventive strategies for these disorders. Furthermore, treatments are mainly symptomatic and can at best temporarily slow down disease progression.[] Moreover, lack of treatment options has led to an increasing number of people to use “natural” and herbal medicines in an attempt to prevent or delay the deleterious effects of ageing as longevity and good health have always been desirable goals for humans.

Various herbal medicines and/or their bioactive compounds have been found to exert significant therapeutic effect in vitro model of neurodegenerative diseases. Pharmacological studies of PMT extract claimed that this medicinal plant may be beneficial in preventing PD[] and AD.[] Furthermore, TSG [Figure 8], one of the bioactive compounds purified from its roots significantly antagonized age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of AD[] and possessed neuroprotection in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease.[Ginkgo biloba and Lycopodium serratum (Huperzine A), through various randomized, double-blind, placebo-controlled, parallel and multi-center clinical trials have been assessed for their clinical efficacy and safety in AD treatment.[,] Their claimed neuroprotective therapeutic activity was significantly expressed on mild AD clinical cases.

Few clinical trials have investigated the potential therapeutic activity of PMT in neurodegenerative diseases. Chen et al. observed the clinical effect of PMT extract on AD.[] The findings suggested that the scores for the Mini-Mental State Examination and the Ability of Daily Living Scale were significantly improved in the treatment group compared to the Chinese herb control group and the western medicine control group (P < 0.01). Moreover, in a randomized, Piracetam-controlled, single-center clinical trial, P. multiflorum (Shouwu yizhi capsule) was evaluated as monotherapy for VaD.[] The authors found that the total clinical effective rate was 71.25% and that the herbal medicinal had obvious therapeutic effect on VaD, with no relative adverse drug reactions.

DCB-AD1 is a new drug derived from PMT and a medical team in Taiwan is proposing a Phase II double-blind, randomized, placebo-controlled and parallel clinical trial to assess its efficacy and safety in patients with mild to moderate AD.[] We therefore believe that further high quality clinical studies on PMT and its isolated bio-compounds, as well as the herbal mixtures resulted, will assess its actual clinical value and could lead to the discovery of new drugs for effective treatment and prevention of neurodegenerative diseases.

CLINICAL CASES OF POLYGONUM MULTIFLORUM-INDUCED HEPATOTOXICITY

Herbal medicines are generally sold as food supplements, and as a consequence, therapeutic indications, efficacy, and safety are influenced by different opinions, according to the clinical or traditional experience of various folk medicines available in each country.[] The market regulation of herbal medicines is not harmonized because there are different regulations in European, Asian and North American countries, and as a consequence, this lack of rules gives poor guarantee of clinical safety.[] Many herbal products have been shown to cause severe toxicity, but, despite the potential toxicity, there is widespread use among eastern and western general population. Information on clinical issues of herbal medicines are scarcely available and even if they have been reported, unlike what happens general practitioners may not be fully informed since correct use and safety of herbal medicinal products is not taught by academic institutions in medicine faculties.[] The current situation requires the knowledge, recognition and monitoring of adverse reactions through pharmacovigilance activities.

Herbal hepatotoxicity or herb-induced liver injury is rare and represents a bundle of disorders, each characterized by a specific herb or herbal mixture considered as potentially hepatotoxic.[] Any individual herb with its multiple chemical constituents may target different liver cell types and/or different subcellular structures, causing likely different diagnostic markers for potentially hepatotoxic herbs and injury types with no single marker characteristic for herbal liver damage.[P. multiflorum (Shou-Wu-Pian and Shen-Min have been the most-well known products), being one of the most famous Chinese herbs to treat several diseases and medical conditions including dizziness with tinnitus, premature greying of hair, lumbago, spermatorrhea, leucorrhea, constipation and even chronic hepatitis B,[,,] has also been ranked in the top five of individual herbs or used most frequently in TCM formulations to induce hepatotoxicity.[] Several cases of hepatotoxicity due to PMT have been reported in patients from Australia, China, Italy, Japan, The Netherlands and Slovakia taking the product for hair loss, chronic prostatitis and to boost the immune system.[,,,,,]

The patients had a history of having ingested PMT in various forms (tea boil with PMT, liquor made of PMT, honey-soaked out with PMT, and the powder of dried PMT). However, it raised the issue concerning the form of the intake with the relation to the severity of hepatotoxicity.[] The processed roots of PMT have displayed lower rates of toxicity as reported in animal experiments.[] Processing appears to significantly reduce the amount of chemicals like 2,3,4′5-tetrahydroxystilbene-2-O-β-Dglucoside, but it remains to be determined if this can explain reduced toxicity in humans. For raw PMT, the toxicity of water decocta appears to be higher than that of acetone extract. Meanwhile, the toxicity of acetone extract of unprocessed PMT is considerably higher than that of acetone extract of processed PMT. High-performance liquid chromatography analyses and nuclear magnetic resonance analysis revealed that the contents of characteristic compounds in raw PMT were changed after processing: The content of 2,3,4Ͳ,5-tetrahydroxystilbene 2-O-β-D-glucoside was decreased by 55.8%, whereas the content of anthraquinone emodin was increased by 34.0%.[,] Thus, suggesting that processing should reduce the toxicity of P. multiflorum.

CONCLUSION

Plants have been selected and use empirically as drugs for centuries, initially as traditional preparations then as pure active principles, with the knowledge and accumulated practice passing from generation to generation.[] Herbal medicine, phytotherapy, phytomedicine, complementary and alternative medicine, ethnomedicine, herbal medicinal product and dietary supplements are all terms used interchangeably to denote the use of botanicals in healthcare and are therefore used as such in this text.[] The human population is a total mixture, unlike selected batches of laboratory animals (same age, weight, sex, strain, etc.). For this reason, human beings do not respond uniformly to one or more drugs or even herbal medicines. Our genetic make-up, ethnic background, sex, renal and hepatic functions, diseases and nutritional states, ages and other factors such as the route of administration, all contribute toward the heterogeneity of our responses.[]

Pharmacological studies have demonstrated that PMT. extracts and/or its isolated pure compound possessed various biological activities such as anti-bacterial, anti-inflammatory, anti-diabetic, anti-cancer, anti-oxidant and exerting preventing activity against neurodegenerative diseases as well. Clinical investigations have enlightened its claimed therapeutic action in anti-inflammatory, dyslipidemia, sleep disorders and neurodegenerative diseases. A general lack of knowledge of the interaction potentials of concurrent use of herbal medicines with prescription and/or over-the counter medicines poses a great challenge for health care professional and safety concern for the patients. In the recent years, due to increasing reports of herbal-induced hepatotoxicity, the clinical efficacy and safety of P. multiflorum and/or its isolated compounds have attracted much interest. The clinical presentation and severity of P. multiflorum can be highly variable, ranging from mild hepatitis to acute hepatitis failure requiring transplantation.

Pharmacists and technicians, as well as physicians, dieticians, and other health care providers must become knowledgeable about herbal supplements and prospectively seek information regarding their patients’ use of unconventional medicines to avoid adverse consequences. Consumers need to be reminded that herbs are composed of chemicals that may, in some cases be toxic, especially if large quantities are ingested. Furthermore, much developed countries and scientific societies are encouraged to conduct clinical studies on P. multiflorum and/or its isolated compounds in order to evaluate their claimed therapeutic activities.

Li Ching Yuen was quite the extraordinary man. As a Chinese herbalist, he lived 256 years or 197 by his own account. Either way this is far more than is recognized as the maximum human life span.

Li Ching Yuen

The famous photo of Li Ching Yuen holding what appears to be a Ginseng root.

(The longest confirmed lifespan comes from Shirali Muslimov with the French woman Jeanne Calment, at 122. Another front runner, with similar debate about his, is Shirali Muslimov at an alleged 168 years old.

This modern day Methuselah had the picture taken above in 1927, a few years before his death, at the invitation of general Yang Sen in Wan Xian, Szechuan. The general, fascinated by his age and the youthfulness he displayed despite it, investigated his background and later published a report with his findings.

The New York Times covered Li Ching-Yuen several times including after his death in 1933.

Li Ching-yun, a resident of Kaihsien, in the Province of Szechwan, who contended that he was one of the world’s oldest men, and said he was born in 1736 — which would make him 197 years old — died today.

A Chinese dispatch from Chung-king telling of Mr. Li’s death said he attributed his longevity to peace of mind and that it was his belief every one could live at least a century by attaining inward calm.

Compared with estimates of Li Ching-yun’s age in previous reports from China the above dispatch is conservative. In 1930 it was said Professor Wu Chung-chien, dean of the department of education in Minkuo University, had found records showing Li was born in 1677 and that the Imperial Chinese Government congratulated him on his 150th and 200th birthdays.

A correspondent of THE NEW YORK TIMES wrote in 1928 that many of the oldest men in Li’s neighborhood asserted their grandfathers knew him as boys and that he was then a grown man.

According to the generally accepted tales told in his province, Li was able to read and write as a child, and by his tenth birthday had traveled in Kansu, Shansi, Tibet, Annam, Siam and Manchuria gathering herbs. For the first hundred years he continued at this occupation. Then he switched to selling herbs gathered by others.

Wu Pei-fu, the war lord, took Li into his house to learn the secret of his living to 250. Another pupil said Li told him to “keep a quiet heart, sit like a tortoise, walk sprightly like a pigeon and sleep like a dog.”

According to one version of Li’s married life he had buried twenty-three wives and was living with his twenty-fourth, a woman of 60. Another account, which in 1928 credited him with 180 living descendants, comprising eleven generations, recorded only fourteen marriages. This second authority said his eyesight was good; also, that the finger nails of his right hand were very long, and “long” for a Chinese might mean longer than any finger nails ever dreamed of in the United States.

Li Ching Yen Younger

Li Ching Yuen at a younger age. (Not clear of if he’s the tall guy or one of the others.)

And here’s a few more details from Wikipedia:

One of his disciples, the Taijiquan Master Da Liu… reports that his master said that his longevity “is due to the fact that I performed the exercises every day – regularly, correctly, and with sincerity – for 120 years.”

Certainly his practice of qigong and exercises was a contributor to his longevity.

His diet was made up primarily of herbs, along with rice wine (suggesting that many of these were in tincture form). According to many immortal legends of Daoist hermits, one of the ways to live far longer than most humans is to gradually shift away from a diet of regular food and subsist mostly on the tonic herbs.

Although there is no way it can be 100% verified as a fact either way, Yuen certainly was an old man. And it wouldn’t become legendary without some amount of truth to the story. Plus he’s not the only one to achieve such legendary status. Not only in age, but in sexual prowess. The man from which Fo-Ti (He Shou Wu) got its name, has a similar story.

The commonalities of such legends, including how to live your life and the taking of tonic herbs, is something well worth doing for anyone looking to live an advanced age, even just 100 years or beyond today.

Extra tricks My Dad and I use….. They are not necessary for Hair Growth Explosion though!

Momatomix Color Paste Conditioner – simply mix activated charcoal powder with Momatomix drops and mix into a paste apply to hair…. let it sit for 10-30 minutes and wash it out….

Pure Lemon Juice Scalp washing treatments also work wonders…especially with raw onion juice conditioner!!!!

 

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My 2 Cents About Copper Worth A Million Bucks

The other day I was eating lunch with a friend and colleague and he mentioned that copper can increase the risk of cancer. This was not the first time I had heard something scary about copper. Last year, another friend (a medical doctor) also mentioned copper’s association with cancer, especially hormonal types. How could something so integral to our body be so bad I wondered?

I researched it. Just like I suspected, copper is essential to good health. We don’t need a lot of copper, but certain healthy amounts are vital and essential to our health and well-being. It’s all about balance! 

Copper is required for the formation of about 50 enzymes and it’s needed for our transporters, which shuttle hormones and neurotransmitters all over your body. Copper protects the lining of blood vessels and myelin. It supports energy production.

Did you hear me? Energy!  I think one of the most important facts about copper is how it supports the healthy functioning of two major enzymes in your body, one is SOD and the other is DAO.

SOD = superoxide dismutase: This enzyme repairs cells and keeps them from getting killed by superoxide! SOD protects mitochondria, and has anti-cancer activity. Without adequate levels of the enzyme SOD you will likely get cardiovascular disease. Copper helps increase SOD.

DAO = diamine oxidase: This enzyme breaks down histamine from all the foods you eat. There are hundreds of foods that contain histamine (it can cause migraines by the way). DAO is your body’s natural anthistamine. Copper increases activity and functioning.

Here’s a little known fact that has kept many people dragging all day long, in search of the next cup of coffee or soda. It’s about fatigue. How many of you suffer with chronic fatigue? If you have iron deficiency anemia that doesn’t respond to iron supplementation, and you’re ferritin remains suppressed, you might be copper deficient. You need iron to make hemoglobin, the main component of red blood cells and you cannot absorb iron without copper. Long story short, copper deficiency is sometimes at the heart of resistant iron deficiency anemia. An “RBC copper” blood test can reveal this.  I am a stickler about your test being RBC (or even WBC) because a common mistake is often made by physicians. They often measure “serum” or “plasma” levels. Who cares what is out there? Neither the serum or the plasma portion of your blood contains any clotting factors or red blood cells. Evaluating copper in the plasma or serum doesn’t give you an indication of what’s inside the cell, where the clotting factors are. That’s what you NEED to know. If you’re spending money for your lab test, you have to do it properly, insist if you have to. Blame it on me if you want to, I’ve got your back!

I am trying to teach you how to derive an accurate evaluation of your intracellular copper levels which will prevent misdiagnosis. If you are tested improperly, and you get a clot, it could cost you your life. Let’s pretend for a moment, that you get the serum copper test I told you not to bother with. Let’s say the serum copper is normal or even high. Serum copper reflects an inflammatory condition in the body (which most people have). This inflammation could be due to an autoimmune disease, arthritis, cancer, thyroid imbalances, gastrointestinal disorders, anything. This elevated serum copper could be happening while you have a full-blown deficiency inside your cells. Even your heart cells (heart muscle). You may be deficient in the most important part of your body, your cells but that plasma copper will come back as normal or even high. This is why proper testing matters.

Let me divulge on a tangent about warfarin, the most popular medication used for anti-coagulation (blood thinning) to prevent strokes. Warfarin goes by many popular brand names around the world including Coumadin or Jantoven in the United States, Marevan in Australia, Uniwarfin in India and there may be others. Some people call warfarin “rat poison” because it’s the active agent in some rodenticides. That wouldn’t prevent me from taking it if I had to, you see … you can take any drug and turn it into a rodenticide if you really want to!  Regardless, my article isn’t about weird uses of prescription drugs, it’s about copper, and how a copper deficiency can lead to thicker blood or blood clots. Most doctors don’t test you for that, they go straight to their prescription pad.

Warfarin may be a precursor to Alzheimer’s. We may see this one day come to light with studies. I’m telling you now. I always tell you years before mainstream media because I care. I am telling you this because warfarin is a drug mugger of vitamin K.  That’s why you have to avoid leafy greens and salads while on warfarin, you have to keep vitamin K down. (You must follow these directions from your doctor, I agree that if you’re on a drug, you need to be careful and avoid the drug interactions).  The drug WORKS through this mechanism of depleting K.
But here’s where it all goes awry. Vitamin K is crucial for sphingomyelin and helping you remember things. Before you take warfarin, find out whether or not you have a copper deficiency. Low levels in the cell cause clotting problems. The BIG DEAL NOW is to test properly! Most docs test serum copper levels. Who cares? It is almost always normal causing you to be dismissed.
In comes warfarin to help reduce clot formation!
I’m saying you need to ask your physician to measure copper levels for you, and make sure they are intracellular (either WBC, RBC or look on your CardioION test if you did one).

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Scientific Data on Spring Summer Selenium

Spring Summer Selenium is a high-powered plant-based selenium.

The liquid forumla replicates nature to give you a Massively Powerful Booster for your Natural Immune System.

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P. D. Whanger
Department of Environmental and Molecular Toxicology
Oregon State University
Corvallis, OR 97331

The statements “Selenium may reduce the risk of certain cancers” and “Selenium may produce anticarcinogenic effects in the body” are supported by scientific evidence. There is significant scientific agreement that daily supplementation with selenium may reduce the risk of some cancers and that selenium is anticarcinogenic. This report will examine epidemiological studies, human clinical trials, animal studies, and in vitro studies on selenium’s relationship to cancer. It will examine the efficacy of different forms of selenium and of different levels of selenium supplementation.

I. Selenium

Selenium is classified in a group VIA of the periodic table of elements which includes the nonmetals, sulfur and oxygen, in the periods above selenium, and the metals, tellurium and polonium, in the period below this element (Combs and Combs, 1986a). By period, selenium lies between the metal arsenic and the nonmetal, bromine. Thus, selenium is considered a metalloid, having both metallic and nonmetallic properties. It has an atomic number of 34 and an atomic weight of 79. Elemental selenium, like its sister elements, sulfur and tellurium, can exist in either an amorphous state or one of three crystalline states.

Elemental selenium can be reduced to the -2 oxidation state (selenide), or oxidized to the +4 (selenite) or +6 (selenate) oxidation states. Hydrogen selenide (H2Se) is a fairly strong acid in aqueous systems. The gas is colorless, has an unpleasant odor, and is highly toxic. At low pH, selenite is readily reduced to the elemental state by mild reducing agents such as ascorbic acid or sulfur dioxide. In its oxidized state (+6), selenium can exist as selenic acid or as selenate salts. Selenic acid is a strong acid. Most selenate salts are soluble in water, in contrast to the corresponding selenite salts and metal selenides. Selenates tend to be rather inert and are very resistant to reduction.

The chemical and physical properties of selenium are very similar to those of sulfur. The two elements have similar outer-valence shell electronic configurations and atomic sizes and their bond energies, ionization potentials and electron affinites are virtually the same. Despite these similarities, the chemistry of selenium and sulfur differ in two respects that distinguish them in biological systems. First, in the biological systems, selenium compounds are metabolized to more reduced states whereas sulfur compounds are metabolized to more oxidized states. The second important difference in the chemical behaviors of these elements is in the acid strengths of their hydrides. The hydride, H2 Se, is much more acidic than is H2S. This difference in acidic strengths is reflected in the dissociation behaviors of the selenohydryl groups of selenocysteine and the sulfhydryl groups on cysteine. Hence, while thiols such as cysteine are predominantly protonated at physiological pHs, the selenohydryl groups of selenols such as selenocysteine are predominantly dissociated under the same conditions.

II. Selenocompounds in plants.

The metabolism of selenocompounds in plants has been summarized (Whanger, 1989). Selenium enters the food chain through incorporation into plant proteins, mostly as selenocysteine and selenomethionine (Semet) at normal selenium levels. However, with elevated selenium levels, Se-methylselenocysteine (SeMCYS) can be the predominant selenocompound. As many as eight other selenocompounds have been identified in plants but their concentrations are usually very low except at high selenium levels. Indicator plants (called selenium accumulators) can accumulate extremely large amounts of selenium, ranging from 1000 to 10,000 Fg selenium per gm because they synthesize mostly nonprotein selenoamino acids (Brown and Shrift, 1981). As much as 80% of the total selenium in some accumulator plants is present as SeMCYS and until recently it was thought to be absent in nonaccumulator plants.

The selenium content of plants is dependent upon the region of growth (summarized by Whanger, 1989). Vegetables such as rutabagas, cabbage, peas, beans, carrots, tomatoes, beets, potatoes, and cucumbers contained a maximum of 6 Fg selenium per gm even when grown on seleniferous soils. Vegetables such as onions and asparagus may accumulate up to 17 Fg selenium per gm when grown on these types of soils. Plants which contain deficient levels of selenium are found in the Pacific Northwest, upper Mid-West, the New England states and along the Atlantic coast of the United States. In other parts of the country such as North and South Dakota, Colorado and Western Nebraska plants may contain high levels of this element. Plants can synthesize organic selenium compounds including Semet from inorganic selenium (Burnell and Shrift, 1977). Because of the uneven global distribution of selenium, disorders of both selenium deficiency and selenium excess are known. For example, China has regions with both the lowest and the highest selenium-containing soil in the world (Yang et al, 1989 a,b). Plants of economic importance do not have a selenium requirement for growth and thus plant selenium is for the health of animals including humans.

Although the data are lacking, synthesis of the nonprotein selenoamino acids by plants probably occurs along pathways normally associated with sulfur metabolism. Conversion of selenocysteine to SeMCYS in accumulators has been shown to involve the transfer of a methyl group from S-adenosylmethionine, analogous to the synthesis of S-methylcysteine (Neuhierl et al, 1999). Even though the primary source of selenium in soil is inorganic, mostly selenate, Astragalus accumulators have been shown to synthesize SeMCYS when supplied with Semet (Chen et al, 1970). The ability of the accumulators to exclude selenoamino acids from proteins has been suggested as a reason for their selenium tolerance. Similar mechanisms apparently operate in selenium enriched plants such as garlic, broccoli, onions and wild leeks where the nonprotein selenoamino, SeMCYS, is the predominant one present.

Most of the selenium in enriched wheat grain (Olson et al, 1970), corn and rice (Beilstein et al, 1991) and soybeans (Yasumoto et al, 1984) is Semet. Semet is the predominant form of selenium in selenium enriched yeast (Ip et al, 2000a). Selenium enriched yeast is the most common source of selenium available commercially (Schrauzer, 2000). The selenoamino acid, Semet, is also available for the public. The major form of selenium is SeMCYS in selenium enriched garlic (Ip et al, 2000a), onions (Cai et al, 1995), broccoli florets (Cai et al, 1995) and sprouts (Finley et al, 2001), and wild leeks (Whanger et al, 2000).

III. Selenocompounds in animals

A brief metabolic pathway for selenium metabolism in animals has been presented (Ip, 1998). Organic selenium such as Semet or inorganic selenium can be converted to a common intermediate, hydrogen selenide. There are two possible pathways for the catabolism of Semet. One is the transsulfuration pathway via selenocystathionine to produce selenocysteine, which in turn is degraded to hydrogen selenide by the enzyme, $-lyase (Mitchell and Benevenga, 1978). The other pathway is the transamination-decarboxylation pathway. It was estimated that 90% of the methionine is metabolized through this pathway and thus could be the major route also for Semet catabolism. SeMCYS is the predominant selenocompound formed in selenium enriched garlic at relatively low concentrations, but γ-glutamyl-Se methyl selenocystine is the predominant one at high selenium concentrations (Dong et al, 2001). Even though this glutamyl derivative may be the predominant one, it is hydrolyzed in the intestinal tract and the absorbed SeMCYS cleaved by a lyase to form methylselenol (Dong et al, 2001). Thus, this glutamyl derivative is metabolized like SeMCYS at the tissue level. SeMCYS is converted to methylselenol directly when cleaved by beta-lyase and unlike Semet it cannot be incorporated nonspecifically into proteins. Since SeMCYS can be converted directly to methylselenol, this is presumably the reason it is more efficacious than other forms of selenium.

When rats are injected with selenite, the majority of the selenium is present in tissues as selenocysteine (Olson and Palmer, 1976; Beilstein and Whanger, 1988). As expected, no Semet was found under the conditions of these studies. In contrast to plants, there is no known pathway in animals for synthesis of Semet from inorganic selenium, and thus they must depend upon plant or microbial sources for this selenoamino acid. However, animals can convert Semet to selenocysteine. One day after injection of Semet there is about three times as much Semet as selenocysteine in tissues, but five or more days afterwards the majority (46-57%) of the selenium is present as selenocysteine (Beilstein and Whanger, 1986).

A total of 24 selenoproteins have been identified in eukaryotes (Gladyshev, 2001). These selenoproteins have been subdivided into groups based on the location of selenocysteine in selenoprotein polypeptides. The first group (called glutathione peroxidase, GPX) is the most abundant and includes proteins in which selenocysteine is located in the N-terminal portion of a relatively short functional domain. These include the four GPXs, selenoproteins P, Pb, W, W2, T T2 and BthD (fromDrosophila). The second group of eukaryotic selenoproteins is characterized by the presence of selenocysteine in C-terminal sequences. These include the three thioredoxin reductases and the G-rich protein from Drosophila. Other eukaryotic selenoproteins are currently placed in the third group that consists of the three deiodinase isozymes, selenoproteins R and N, the 15 kDa selenoprotein and selenophosphate synthetase. The four GPXs are located in different parts of tissues and all detoxify to various degrees hydrogen peroxide and fatty acid derived hydroperoxides and thus are considered antioxidant selenoenzymes. The three deiodinases convert thyroxine to triiodothyronine, thus regulating thyroid hormone metabolism. The thioredoxin reductases reduce intramolecular disulfide bonds and, among other reactions, regenerate vitamin C from its oxidized state. These reductases can also affect the redox regulation of a variety of factors, including ribonucleotide reductase, the glucocorticoid receptor and the transcription factors (Holmgren, 2001). Selenophosphate synthetase synthesizes selenophosphate, which is a precursor for the synthesis of selenocysteine.(Mansell and Berry, 2001). The functions of the other selenoproteins have not been definitely identified.

Selenium is present in all eukaryotic selenoproteins as selenocysteine (Gladyshev, 2001). Semet is incorporated randomly in animal proteins in place of methionine. By contrast, the incorporation of selenocysteine into proteins known as selenoproteins is not random. Thus, by contrast to Semet, selenocysteine does not randomly substitute for cysteine. In fact, selenocysteine has it own triplet code (UGA) and is considered to be the 21st genetically coded amino acid. Interestingly, UGA has a dual role in the genetic code, serving as a signal for termination and also a codon for selenocysteine. Whether it serves as a stop codon or encodes selenocysteine depends upon the location of what is called the selenocysteine insertion sequence (Mansell and Berry, 2001).

A number of reviews have been written on the chemopreventive effects of selenium including most recently those by Combs and Gray (1998), Ganther (1999), Ip (1998), Schrauzer (2000), El-Bayoumy (2001) and Fleming et al (2001). The mechanism for selenium as an anticarcinogenic element is not known but several speculations have been advanced. It is well established that the most effective dose of selenium for cancer protection is at elevated levels, often called supernutritional or pharmacological levels. The suggested mechanisms for cancer prevention by selenium include its effects upon cell cycle (called apoptosis, probably the most accepted possibility), its role in selenoenzymes, its effects upon carcinogen metabolism, its effects upon the immune system, and its specific inhibition of tumor cell growth by certain selenium metabolites.

 

 

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IV. Epidemiological studies

There have been a number of epidemiological studies in the United States and throughout the world on the relationship between selenium and cancer. Shamberger and Frost (1969) reported that the selenium status of humans may be inversely related to the risk of some kinds of cancer. Two years later, Shamberger and Willis (1971) in more extensive studies indicated that the mortality due to lymphomas and cancers of the gastrointestinal tract, peritoneum, lung, and breast were lower for men and women residing in areas of the United States that have high concentrations of selenium in forage crops than those residing in areas with low selenium content in the forages. Those studies were supported by a later analysis of colorectal cancer mortality using the same forage data (Clark et al, 1981). A 27-country comparison revealed that total cancer mortality rate and age-corrected mortality due to leukemia and cancers of the colon, rectum, breast, ovary and lung varied inversely with estimated per capita selenium intake (Schrauzer et al, 1977). Similar results were also reported in China, a country where selenium intakes range from deficient to toxic levels (Yu et al, 1985).

Lower selenium levels were found in serum collected from American subjects one to five years prior to diagnosis of cancer as compared to those who remained cancer free during this time (Willett et al, 1983). That association was strongest for gastrointestinal and prostatic cancers. Evidence that low serum selenium is a prediagnostic indicator of higher cancer risk was subsequently shown in studies conducted in Finland (Salonen et al, 1984) and Japan (Ujiie et al, 1998). In additional case-control studies, low serum or plasma selenium were found to be associated with increased risk of thyroid cancer (Glattre et al, 1989), malignant oral cavity lesions (Toma et al, 1991), prostate cancer (Brooks et al, 2001), esophageal and gastric cancers (Mark et al, 2000), cervical cancer mortality rates (Guo et al, 1994) and colorectal adenomas (Russo et al, 1997). A decade long prospective study of selenium status and cancer incidences indicated that initial plasma selenium concentration was inversely related to subsequent risks of both non-melanoma skin cancer and colonic adenomatous polyps (Clark et al, 1993). Patients with plasma selenium levels less than 128 ng/ml (the average normal value) were four times more likely to have one or more adenomatous polyps. An 8-year retrospective case control study in Maryland revealed no significant association of serum selenium level and cancer risk at sites other than the bladder (Helzlsouer et al, 1989), but those with low plasma selenium levels had a 2-fold greater risk of bladder cancer than those with high plasma selenium. In a study with Dutch patients the mean selenium levels were significantly less than that of controls in men, but no differences were found in plasma selenium levels between control women and those with cancer (Kok et al, 1987). No significant associations in three other studies were found between serum selenium concentration and risk to total cancers (Coates et al, 1988) or cancers of the lungs, stomach, or rectum (Nomura et al, 1987 and Kabuto et al, 1994). In other work, significant increases of urinary selenium excretion were found in Mexican women with cervical uterine cancer as compared to controls (Navarrete et al, 2001).

In four studies low toenail selenium values were associated with higher risks of developing cancers of the lung (van den Brandt et al, 1993a), stomach (van den Brandt et al, 1993b), breast (Garland et al, 1995) and prostate (Yoshizawa et al, 1998). In contrast, in four other studies no significant differences were found between cancer cases and controls (Noord et al, 1987, Hunter et al, 1990, Rogers et al, 1991 and Veer et al, 1990). It has been suggested that the reason for those not showing a relationship is because the selenium intakes of most of the subjects tested were below that necessary for protection (Schrauzer, 2000). Obviously these results indicate that many factors must be taken into consideration when evaluating plasma and toenail selenium concentrations in relation to cancer incidence.

V. Human Trials.

In spite of advances in diagnosis and treatment, cancer continues to be a major health burden. With the fear associated with diagnosis of cancer, it is not surprising that the public may have considerable interest in easily implemented measures, such as dietary modification or use of vitamin and trace element supplementation for cancer prevention. Promising results have been obtained, however, to indicate that selenium supplementation is effective in reduction of cancer in humans.

There have been six trials conducted on the effects of selenium supplementation on the incidence of cancer or biomarkers in humans and all of them have shown positive effects of selenium. Three of these were conducted in China and one each in India, Italy and in the United States. The first human intervention trial to prevent cancer with selenium in humans was conducted in Qidong, a region north of Shanghai, China, with a high incidence of primary liver cancer (PLC). Subjects were given table salt fortified with 15 ppm selenium as sodium selenite which provided about 30 to 50 micrograms selenium daily for eight years (Yu et al, 1991, 1997). This resulted in a drop of the PLC incidence to almost one-half (27.2 per 100,000 populations versus 50.4 per 100,000 populations consuming ordinary salt). Upon withdrawal of selenium from the treated group, the PLC incidence began to rise. In a separate study, risk populations receiving selenite salt as a source of selenium also showed a significant reduction in the incidence rate of viral infectious hepatitis, a major predisposing PLC risk factor in this region (Yu et al, 1989). The selenium fortified salt was distributed to the general population of 20,800 persons. Six neighboring townships served as controls and were given normal table salt.

In a second trial, members of families at risk of PLC were either given 200 micrograms selenium daily in the form of high-selenium yeast or a placebo (Yu et al, 1997). During the 2-year study period, 1.26% of the controls developed PLC versus 0.69% in those given selenium enriched yeast. Furthermore, of 226 Hepatitis B surface antigen carriers, seven of 113 subjects in the placebo group developed PLC during four years as opposed to no cases in those taking selenium enriched yeast.

A third human trial on the effects of selenium on cancer was also conducted in China with 3,698 subjects. This intervention trial was conducted from 1984 to 1991 in Linxian, China, a rural county in Henan Province, where the mortalities from esophageal cancer are among the highest in the world (Blot et al, 1993). The results indicated that a treatment containing selenium (50 micrograms Se/day as Se enriched yeast plus vitamin E and $-carotene) produced a modest protective effect against esophageal and stomach cancer mortality among subjects in the general population (Li et al, 1993; Taylor et al, 1994; Blot et al, 1995). Probably the reason for only a modest reduction of cancer by selenium is because only 50 micrograms were given daily in contrast to other studies where up to 200 micrograms were given per day.

In the study conducted in India, 298 subjects were used. One-half of the subjects with precancerous lesions in the oral cavity were supplemented with a mixture of four nutrients [vitamin A, riboflavin, zinc and selenium (100 micrograms daily for six months and 50 micrograms the final six months as selenium enriched yeast)] and compared to controls (also 149 patients) receiving placebos (Prasad et al, 1995). The frequency of micronuclei and DNA adducts were significantly reduced in the supplemented groups at the end of the one year study. The adducts decreased by 95% in subjects taking selenium with all categories of lesions and by 72% in subjects without lesions. No such effects were noted in the placebo group.

In the Italian study subjects were given a mixture called ‘Bio-selenium’ which provided 200 micrograms selenium as L-selenomethionine daily plus zinc and vitamins A, C and E for five years, and compared to those taking a placebo (Bonelli et al, 1998). A total of 304 patients participated in this study and the incidence of metachronous adenomas of the large bowel evaluated. Patients with prior resected adenomatous polyps were used in a randomized trial and new adenomatous polyps were noted. The observed incidence of metachronous adenomas was 5.6% in the group given the ‘Bio-selenium’ mixture versus 11% in the placebo group.

One of the most exciting clinical trials on selenium and cancer in humans was conducted in the United States. A simple experimental design in a double-blind, placebo-controlled trial with 1312 older Americans with histories of basal and/or squamous cell carcinomas of the skin were used (Clark et al, 1996, 1998). The use of a daily oral supplement of selenium enriched yeast (200 µg Se/day) did not affect the risk of recurrent skin cancers. However, supplementation with selenium as selenium enriched yeast reduced the incidence of lung, colon and prostate cancers respectively by 46, 58 and 64%. Restricting the analysis to the 843 patients with initially normal levels of prostate specific antigen, only four cases were diagnosed with cancer in the selenium treated group but 16 cases were diagnosed in the placebo group after a 2-year treatment lag (Clark et al, 1998). Even though Clark et al (1996) did not observe any effect of selenium on skin cancer in their study, the results strongly indicated that other types of skin disorders may be reduced by selenium.

The author is aware of at least three human trials [two in the United States (University of Arizona; and the SELECT trial at NCI; Klein et al, 2001), and one in Europe (PRECISE, Rayman, 2000)] presently under way to confirm the results of this American investigation.

Finally, in another trial, topical application of Semet was effective in protecting against acute ultraviolet irradiation damage to skin of humans (Burke et al, 1992a). Maximal protection appeared to be attained at concentrations between 0.02% and 0.05%.[1][1]

VI. Selenium and tumors in small animals.

There have been more than 100 trials conducted with small animals on the relationship of tumor incidences to selenium status (Combs and Combs, 1986b; Combs and Gray, 1998). Interestingly, the first evidence that selenium may counteract tumors was presented in 1949 where the addition of selenium to a diet for rats significantly reduced tumors caused by ingestion of an azo dye (Clayton and Bauman, 1949). These results were ignored even by these researchers because of the negative image selenium held at that time. The first evidence of the essentiality of selenium was presented in 1957 (Schwarz and Foltz, 1957), at which time selenium was considered a carcinogenic element. A number of reviews on selenium and carcinogensis in animals have been presented which include those by Milner (1985), Ip and Medina (1987) Medina and Morrison (1988) and Whanger (1992). The chemical carcinogens used to produce tumors in liver, mammary gland, colon, skin, lungs, trachea, pancreas and stomach have been summarized (Whanger, 1992). Two thirds of the animal studies showed significant reductions by selenium in the tumor incidence with one-half showing reductions of 50% or more (Combs and Gray, 1998). In the majority of those studies selenium as selenite was used but that may not have been the most effective form (as noted later) to use. Those results with animals and the epidemiological surveys showing a positive relationship between selenium and cancer incidence were the main motivating factors for conducting human trials.

VII. Tissue cultures.

The present research efforts are primarily focused on the mechanism of cancer reduction by selenium and tissue cultures have been used advantageously to study how tumors are reduced by this element. Research with these cultures also indicates that the beta-lyase mediated production of a monomethylated selenium metabolite, namely methylselenol, from SeMCYS is a key step in cancer chemoprevention by this agent (Ip et al, 2000b). In order for SeMCYS to be effective, cells must possess this beta-lyase. One way to get around this is to use methylselenic acid, which is even effective in cells without this lyase. Although several possibilities have been suggested (Combs and Gray, 1998), the evidence indicates that the likely mechanism in which selenium reduces tumors is through its effects upon apoptosis (Unni et al, 2001; Sinha et al, 1999). Methylselenic acid produced a more robust response at one-tenth the concentration of SeMCYS in the inhibition of cell proliferation and the induction of apoptosis in mouse mammary epithelial cells (Ip et al, 2000b). Apparently these cells have low levels of the beta-lyase. Interestingly the distinction between these two compounds disappears in vivo where their cancer chemopreventive efficacies were found to be very similar. The reason for this is because the beta-lyase enzyme is abundant in many tissues and thus the animal has ample capacity to convert SeMCYS to methylselenol.

Work with the mouse mammary epithelial tumor cells indicate that SeMCYS mediates apoptosis by activating one or more caspases (Unni et al, 2001). Of the caspases, caspase-3 activity appeared to be activated to the greatest extent. Apparently these cells have ample lyases to convert SeMCYS to methylselenol. Further work with these same cells using methylselenic acid produced similar results, providing additional support that monomethylated forms of selenium are the critical effector molecules in selenium mediated growth inhibition in vitro (Sinha et al, 1999). Further research is needed to identify why a monomethylated form of selenium that is required for this effect cannot be fulfilled by other forms of selenium.

VIII. Forms of selenium in foods and supplements.

The efficacy of various selenocompounds using the mammary tumor model has been summarized in Table 1.[2][2] SeMCYS and selenobetaine are the most effective selenocompounds identified thus far against mammary tumorigenesis in animals (table 1). Although selenobetaine is just as effective, SeMCYS is considered to be the most interesting selenocompound because it is the predominant one present in selenium enriched plants such as garlic (Ip et al, 2000a), broccoli florets (Cai et al, 1995) and sprouts (Finley et al, 2001), and onions (Cai et al, 1995). Selenobetaine has never been detected in selenium enriched plants. Therefore, SeMCYS has received the most recent attention as possibly the most useful one for cancer reduction. Except for Semet and selenocystine, the other selenocompounds listed in this table are not present in plants and thus are mostly of academic interest. However, some of them are of therapeutic interest.

Selenobetaine and SeMCYS are good precursors for generating monomethylated selenium (Ip, 1998). Selenobetaine tends to lose a methyl group before scission of the Se-methylene carbon bond to form methylselenol. SeMCYS is converted to methylselenol directly when cleaved by beta-lyase and unlike Semet it cannot be incorporated nonspecifically into proteins. Since these

Table 1. Anticarcinogenic Efficacy of Different Selenium Compounds for reduction of mammary tumors in rats.

Compound Dose of Selenium for 50% Inhibition (ppm)
Se-methylselenocysteine 2
Selenobetaine 2
Selenobetaine methyl ester 2-3
Selenite 3
Selenomethionine 4-5
Selenocystine 4-5
PXSC* 8-10
Triphenylselenonium 10-12
Dimethylselenoxide >10
Trimethylselenonium (No effect at 80 ppm)

*1,4-phenylene bis (methylene) selenocyanate

Data taken from Ip and Ganther, 1993 and Ip et al, 1994a, 1994b.

__________

selenocompounds can be converted directly to methylselenol, this is presumably the reason they are more efficacious than other forms of selenium. Dimethylselenoxide

and selenobetaine methyl ester are converted to dimethylselenide but are less effective for reduction of tumors (Ip, 1998). Trimethylselenonium is essentially not effective in tumor reduction. Thus, there is a negative correlation between the effectiveness of these selenocompounds and the degree of methylation.

Even though Semet is effective against mammary tumors, one disadvantage is that it can be incorporated directly into general proteins instead of converted to compounds which most effectively reduce tumors (Ip, 1998). When this occurs its efficacy for tumor reduction is reduced. For example, when a low methionine diet is fed there is significant reduction in the protective effect of Semet even though the tissue selenium was actually higher in animals as compared to those given an adequate amount of methionine (Ip, 1988). When methionine is limiting, a greater percentage of Semet is incorporated nonspecifically into body proteins in place of methionine because the methionine-tRNA cannot distinguish between methionine and Semet. Feeding diets with Semet to animals as the main selenium source will result in greater tissue accumulation of selenium than other forms of selenium (Ip and Lisk, 1994; Whanger and Butler, 1989). It is not known whether this stored selenium can serve as a reserved pool of this element but the evidence indicates that it is metabolically active (Waschulewski and Sunde, 1988).

With the knowledge of the effects of these selenocompounds as anticarcinogenic agents, it was of interest to investigate the most appropriate methods for delivery to the general population. One obvious approach was to investigate additional methods for expeditious ways to deliver these protective agents through the food system. One strategy in this direction was the investigation of enriching garlic with selenium (Ip et al, 1992). The addition of selenium enriched garlic to yield three micrograms selenium per gram diet significantly reduced the mammary tumor incidence in rats from 83% to 33%. Similar to garlic, selenium enriched broccoli also reduced mammary tumors from 90% to 37% (Finley et al, 2001).

Selenium enriched garlic was shown to be twice as effective as selenium enriched yeast in the reduction of mammary tumors (table 2). The total number of tumors as well as the incidence of tumors was reduced to a greater extent by enriched garlic than enriched yeast. Chemical speciation of selenium in these two products indicated that Semet was the predominant form of selenium in enriched yeast whereas SeMCYS (as the glutamyl derivative) was the predominant form of selenium in enriched garlic (Ip et al, 2000a). The glutamyl derivative is considered a carrier of SeMCYS and both of these compounds were shown to be equally effective in the reduction of mammary tumors (Dong et al, 2001). These results are consistent with those in table 1 where SeMCYS was more effective than Semet for reduction of mammary tumors. The chemical composition of selenocompounds in these two sources of selenium is apparently responsible for this difference in efficacy.

Using another model, selenium enriched broccoli florets (Finley et al, 2000; 2001; Finley and Davis, 2001) as well as enriched broccoli sprouts (Finley et al, 2001) significantly reduced colon tumors in rats. This is intriguing because colon cancer is the third most common newly diagnosed cancer in the United States, resulting in about 55,000 deaths per year due to this type of cancer (American Cancer Society, 2000).

Table 2. Mammary Cancer Prevention by Selenium enriched Garlic or Selenium enriched Yeast in the DMBA and MNU Models

Model Treatment Dietary Selenium (µg/g) Tumor Incidence Total number of Tumors Percentage inhibitiona
DMBA none Se-garlic Se-yeast 0.1 3.0 3.0 26/30 11/30b 19/30c 74 25b 49c 66 34
MNU none Se-garlic Se-yeast 0.1 3.0 3.0 28/30 10/30b 20/30c 80 24b 55c 70 31

a Calculated based on total tumor yield data.

bP < 0.05, compared to the corresponding Se-yeast group.

cP < 0.05, compared to the corresponding control group.

DMBA = dimethylbenz [a] anthracene; MNU = Methylnitrosourea

Taken from Ip et al, 2000a

____________

Selenium enriched broccoli was more effective than selenite, selenate or Semet in the reduction of induced colon carcinogenesis (Feng et al, 1999 and Davis et al, 1999). In contrast, selenite, selenate and Semet were more effective for induction of GPX activity than selenium enriched broccoli (Finley and Davis, 2001). This indicates that the plant converts the selenium to more effective forms for reduction of these tumors and these results emphasize the need to study the effects of selenium in food forms.

Similar to chemically induced colon tumors there were significantly fewer intestinal tumors when mice which have a genetic defect for development of intestinal tumors were fed selenium enriched broccoli (Davis et al, 2002). These results along with data above indicate that selenium enriched broccoli is effective against both chemically and genetically induced intestinal tumors. Data from work with another strain of mice which develop spontaneous intestinal tumors is consistent with these results where selenium deficiency resulted in activation of genes involved in DNA damage (Rao et al, 2001).

IX. Level of selenium necessary for nutritive benefit

The Chinese data have been used almost exclusively to establish the required levels of selenium for nutritive benefit as well as to establish the safe levels for humans (Yang et al, 1989b; Yang and Zhou, 1994). It is fortunate to have a country like China where areas vary from deficient to toxic levels of selenium, and this has made it convenient to collect critical information on the metabolism and effects of various levels of selenium in humans. Significant correlations have been found between daily selenium intake and selenium content of whole blood, plasma, breast milk, and 24 hour urine (Yang et al, 1989a). Highly significant correlations were also found between levels of whole blood selenium and hair selenium, fingernail selenium and toenail selenium, hair selenium and fingernail or toenail selenium, and whole blood selenium and toenail or fingernail selenium. Morphological changes in fingernails were used as the main criterion for clinical diagnosis of selenosis (Yang et al, 1989b). The fingernail changes and loss of hair are the main signs of excess selenium intakes. With excess selenium intakes, the fingernails become brittle and are easily cracked. The data collected on Chinese subjects are summarized in table 3.

An intake of nearly 5 mg of selenium resulted in definite occurrence of selenosis, characterized by hair and nail losses. One suggested reason the subjects were able to tolerate this high level of selenium is because they consumed a high fiber diet. The low adverse effect level of dietary selenium was calculated to range between 1540 and 1600 micrograms daily. However, some effects were noted in individuals with a daily intake of 900 micrograms. The maximum safe dietary selenium intake was calculated to be about 800 micrograms per day, but there were some individuals where an amount of 600 micrograms per day was the maximum safe intake. In order to provide a safety factor, the maximum safe dietary selenium intake was suggested as 400 micrograms per day. A level of about 40 micrograms daily was suggested as the minimum requirement, and an intake of less than 11 micrograms daily will definitely result in deficiency problems. Deficiency of selenium in humans results in a cardiac and muscular disorder called Keshan disease, and deficiency of selenium is thought to be one of the contributing factors to another disorder called Kaschin-Beck disease.

Table 3. Health Effects of Various Levels of Dietary Selenium Intakes

Average AduIt Dietary

Selenium Intakes

(µg/d) (µg/KgBW) Forms Effects on Human Health

__

*4990 ± 1349 90 Cereal-based plant diet Occurrence of selenosis with hair & nail loss

in seleniferous area

*1660 30 Cereal-based plant diet Adverse effect level (AEL) of dietary Se intake

in seleniferous area

*1540 ± 653 28 Cereal-based plant diet Low adverse effect level of dietary Se intake

in seleniferous area (mean LOAEL)

*×900 17 Cereal-based plant diet Individual low level causes toxicity

in seleniferous area (individual LOAEL)

*819 ± 129 15 Cereal-based plant diet Maximum safe dietary Se intake

in seleniferous atea (NOAEL, mean)

*600 11 Cereal-based plant diet Individual maximum safe dietary Se intake

in seleniferous atea (NOAEL, individual)

400 – Natural Diet Suggested maximum safe dietary Se intake

40 0.7 75% of dietary Se from Suggested adequate dietary Se requirement

selenomethionine

< 11 < 0.2 Cereal-based plant diet Prevalence of Keshan disease and

in Keshan disease area Kaschin-Beck disease

*Calculated by regression equation.

Data modified from: Yang and Zhou (1994). .

_______________

X. Conclusion.

The RDA for selenium is 55 micrograms for healthy adults, with 40 micrograms selenium as the minimum requirement. Less than 11 micrograms selenium will definitely put people at risk of deficiency that would be expected to cause damage. Daily doses of 100 to 200 micrograms

selenium inhibit genetic damage and cancer development in humans. About 400 micrograms

selenium per day is considered an upper safe limit. Clearly doses above the RDA are needed to

inhibit genetic damage and cancer. Despite concerns about the toxicity of higher dietary levels of selenium, humans consuming up to 600 micrograms of selenium daily appear to have no adverse clinical symptoms.[3][3]

Both animal and human data indicate that more than 100 and up to 200 micrograms of selenium are necessary for greatest reduction of cancer. This is because a methylated form of selenium is necessary for maximum reduction of cancer, and the methylated forms are present at highest levels with elevated intakes of this element. In most human trials, the subjects were supplemented with 200 micrograms selenium per day and in trials where only 50 micrograms were supplemented there was not as much reduction of cancer. Therefore, the selenium requirement for maximum reduction of cancer appears to be at least four times the RDA. However, since only 50 to 200 micrograms additional selenium have been used, it is not possible to indicate which level will give maximum protection. For example, it is not known whether supplemental levels of selenium above 200 micrograms daily will provide any additional protection against cancer.

Selenium enriched yeast is the most common source of selenium available commercially and it also has been the most used selenium source in human trials. Semet is the major form in enriched yeast but SeMCYS is the predominant form in enriched plants such as garlic and broccoli. Selenium enriched garlic was shown to be twice as effective as enriched yeast in reduction of mammary tumors in rats. Apparently, the reason SeMCYS is more effective is because it is converted directly to methylselenol, the suspected biologically active form of selenium for reduction of tumors. However, it is not known whether providing twice as much selenium as enriched yeast will give the same benefits as enriched garlic. Therefore, in addition to enriched yeast, selenium enriched food plants such garlic, broccoli and onions appear also to be an effective and safe method for delivery of selenium to the general population. Nevertheless, regardless of the source of selenium it is apparent that additional intakes of this element by humans will reduce the incidence of cancer.

It has been estimated that one-third of the cancers in humans are environmentally related. The results in this report indicate that on an average there could be 50% reduction of cancer through increased selenium ingestion in humans. If the 50,000 deaths due to colorectal cancer, the 41,800 deaths due to prostate cancer in men, or the 43,300 breast cancer deaths in women could be reduced by one-half with selenium, this would be a very significant contribution to human health.

___________________________

Phil D. Whanger

Department of Environmental and Molecular Toxicology

Oregon State University

A copy of my curriculum vitae is attached

 

ORDER HERE

 

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Yu, Sh.-Y., Y. J. Zhu and W. G. Li (1997) Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong. Biol. Trace Elem. Res. 56: 117-124.

Yu, Sh-Y. Y-J Zhu W-G Li, Q-S Huang, C. Zhi-Huang and Q-N Zhang. (1991) A preliminary report of the intervention trials of primary liver cancer in high risk populations with nutritional supple-mentation of selenium in China. Biol. Trace Elem. Res. 29: 289-294.

Yu, Sh-Y., W-G Li, Y-J Zhu, W-P Yu and C. Hou (1989) Chemoprevention trial of human hepatitis with selenium supplementation in China. Biol. Trace Elem. Res. 20: 15-22.

Yu, S. Y., Y. J. Chu, X. L. Gong, C. Hou, W. G. Li, H. M. Gong and J. R. Xie. (1985) Regional variation of cancer mortality incidence and its relation to selenium levels in China. Biol. Trace Elem. Res. 7: 21-29.

[1][1] These results are consistent with some animal data. Hairless mice treated by topical application of selenomethionine (0.02%) or given drinking water with 1.5 micrograms selenium per ml as selenomethionine had significantly less skin damage due to ultraviolet irradiation (Burke et al, 1992b). This is consistent with an earlier study which indicated that dietary selenium (one microgram/g) fed to mice significantly reduced the number of skin tumors induced by two carcinogenic chemicals plus croton oil (Shamberger, 1970).

[2][2] The incidence of breast cancer is greatest of all cancers in women but it is the third highest cause of all cancer deaths (American Cancer Society, 2000), probably reflecting the improved methods for detecting and treatment of breast cancer compared to other cancers . Although usually not mentioned, a small number of men develop breast cancer with even some deaths. About 400 men die of breast cancer each year compared to 43,300 breast cancer deaths in women.

[3][3] The author is aware of a person who consumed one mg of selenium for two years before toxic signs of selenium occurred. Thus this element appears not as toxic as often believed.

 

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Selenium also helps stop damaged DNA molecules from reproducing. In other words, selenium acts to prevent tumors from developing. “It contributes towards the death of cancerous and pre-cancer cells. Their death appears to occur before they replicate, thus helping stop cancer before it gets started,” says Dr. James Howenstine in A Physician’s Guide to Natural Health Products That Work.

In addition to preventing the onset of the disease, selenium has also been shown to aid in slowing cancer’s progression in patients that already have it. According to the Life Extension Foundation, the use of selenium during chemotherapy in combination with vitamin A and vitamin E can reduce the toxicity of chemotherapy drugs. The mineral also helps “enhance the effectiveness of chemo, radiation, and hyperthermia while minimizing damage to the patient’s normal cells; thus making therapy more of a ‘selective toxin,'” says Patrick Quillin in Beating Cancer with Nutrition.

A 1996 study by Dr. Larry Clark of the University of Arizona showed just how effective selenium can be in protecting against cancer. In the study of 1,300 older people, the occurrence of cancer among those who took 200 micrograms of selenium daily for about seven years was reduced by 42 percent compared to those given a placebo. Cancer deaths for those taking the selenium were cut almost in half, according to the study that was published in the Journal of the American Medical Association.

While the study concluded the mineral helped protect against all types of cancer, it had particularly powerful impacts on prostate, colorectal and lung cancers. Jean Carper, in Miracle Cures, called Dr. Clark’s findings an “unprecedented cancer intervention study” that “bumped up the respectability of using supplements against cancer several notches.”

Accordingly, geography can have a significant impact on diet. In Antioxidants Against Cancer, author Ralph Moss PhD, says one theory for why cancer rates are so high in Linxian, China, dubbed “the ‘world capital’ of cancer,” is that the soil is deficient in the essential minerals selenium and zinc. In Earl Mindell’s Supplement Bible, Earl Mindell RPh PhD, suggests part of the reason American men are five times more likely than Japanese men to die from prostate cancer could be because, in general, “the Asian diet contains four times the amount of selenium as the average American diet.”

 

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Scientific Data on the Parasite Purge 21 Day Detox

Scientific Data on the Parasite Purge 21 Day Detox

https://examine.com/supplements/bladderwrack/

Here’s a vid on what’s in it…

 

 

 

Here is a video on my mindset going into this as a Certified Personal Trainer & Sports Nutritionist…

 

The Detox, it’s inception and how it works via the Mitochondria

 

Additional info on Parasite Purge Momatomix…

Black Genetics the Medical Papyrus 382-385.001

 

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Black Genetics the Medical Papyrus 382-385.003

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*Must Watch Video If You Use Any Over the counter or Prescription Drugs and how they cause disease. Momatomix Greens are the Best Solution!

 

Why Hydrogen is the Nutrient of the Future

 

 

Just use Momatomix Daily!!!! Thats the easiest way to get your Daily Dose of Hydrogen!!!!

 

WHY SHOULD WE TAKE THE PARASITE PURGE 21 DAY DETOX?

Factors That Deplete Minerals From The Body

First and foremost we must understand that we are ultimately made of the earth. The same chemical elements found in soil make up

our bodies. The food we obtain and consume must ultimately have a direct relationship with good healthy mineral -nutrient rich soil

full of healthy live beneficial organisms. Our nutrition must come from plants and animals as we are indeed omnivorous creatures.

These plants and animals must ultimately get their food either directly or indirectly from the soil. It is our mineral-deficient soils

that are likely causing a majority of our modern health issues. Food crops grown on depleted soils produce malnourished bodies

that then fall prey to all sorts of disease. When we lack minerals, we lack vitamins, because minerals are catalysts to vitamins in the

Gain an in-depth picture into your overall health.

“99% of the American people are deficient in minerals, and a marked deficiency in any one of the more important minerals actually results in disease.” (source – Senate Document 264 74th Congress, 1936 [25])

Factors that Deplete Minerals

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Soil Depletion – This is the number one reason that most Americans are mineral deficient. Soil depletion has been well documented since the US Senate made their study back in 1936. Even organically grown vegetables are lacking in minerals – organic farming only addresses the pesticide/chemical issues most typically. The best way to get mineral rich grown fruits and vegetables is through bio-dynamic produce, local CSA’s that practice crop rotation and soil supplementation through compost and other means, and of course growing your own garden you can work on the integrity of the soil. Not to mention, the animals we consume also need to be raised on good quality pastures with good soil conditions as well.

Antacids & Acid blockers – deplete calcium, but often people are unaware as testing is done on blood levels and only 1% of the calcium in the body is in the blood. This doesn’t indicate the loss in the bones/tissues. Antacids/Acid Blockers contain aluminum hydroxide which prevents the absorption of calcium from the intestinal tract.

Low Stomach Acid/Hypochlorhydria – the body needs appropriate stomach acid in order to break down minerals, namely calcium. Also, low stomach acid can be a sign of low zinc because zinc is needed in the body to help produce stomach acid.

Cortisone – used for pain and inflammation can contribute to severe calcium loss with prolonged use. It also depletes potassium. Pharmaceutical Drugs – this is too vast to go into, suffice it to say all drugs deplete the body of a vast amount of nutrients.

Birth Control Pills – deplete magnesium and zinc, along with numerous other vitamins. And since they have a direct impact on our hormones this also plays with our ability to get the minerals needed. They cause excess copper in the body, which can be toxic, this is why zinc becomes depleted as these two minerals are antagonistic to each other.

Coffee – calcium/magnesium are lost in our urine with coffee. It’s a diuretic. You will be losing potassium and sodium as well. The same goes for caffeine in general.

Alcohol- speeds up the excretion of magnesium through the kidneys. It can also deplete, calcium, zinc, iron, manganese, potassium and chromium.

Soda consumption – contains excess phosphorous which leads to reduced body storage of calcium because they compete for

absorption in the intestines. Soday also causes potassium loss.
Gain an in-depth picture into your overall health >> Yes, tell me more!

Sugar– for every molecule of sugar our bodies use 54 molecules of magnesium to process it. Insulin surges use up our zinc. Sugar

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7/8/2016 Factors That Deplete Minerals in the Body

also depletes magnesium, potassium and robs your bones of minerals in general. A high sugar diet results in increased losses of chromium through the urine.

Excess Insulin– causes calcium to be retained by the body through re-absorption by the kidneys. Excess Estrogen – decreases calcium excretion. Same effects as birth control also apply.

Hyperthyroidism– causes increased calcium losses and increased calcium resorption from the bone. Creates the need for more magnesium. Often more copper is needed, along with iodine. Perhaps it would be better stated that deficiencies of selenium play a role in low thyroid hormone production

Stress– depletes magnesium.

The Standard American Diet (S.A.D diet) – the typical diet of minimal fresh foods, higher amounts of refined and processed foods, foods grown on poor/depleted soils, excess phosphorous in these foods depletes calcium and has been shown to cause bone loss. Magnesium and chromium, (and all minerals really) are also lost in processing and due to poor soil.

Excess Grains– phytic acid binds with the minerals in the intestine and blocks absorption, causing them to be excreted unused. Oxalates– oxalic acid is a substance which binds with calcium in the intestinal tract and actually prevents calcium absorption.

(oxalates are found in spinach, beet greens, rhubarb and chard)

Dietary Insufficiency – source of food, how it’s prepared, is it processed or whole real natural foods. And of course, was the food raised properly on mineral rich soils.

Athletes/Excessive exercising– taxes magnesium reserves.

Pregnancy- it takes a lot of nutrients to make a baby, and minerals are no exception. If mother is already low in mineral stores she will become further depleted as her body takes the nutrients to build a healthy baby. Iron is one common mineral deficiency in pregnant and breastfeeding women, namely because the needs for it increase immensely during this time.

Vegetarian/Vegan Diet – the best sources of many minerals are in animal foods. Plant foods grown in poor soil are not enough to supply the dietary needs of minerals. Vegetarians are more vulnerable to iron deficiency as well.

Heavy Metal Toxicity–

• Mercury – amalgam fillings, in certain fish, vaccines. Blocks magnesium and zinc. Mercury binds with magnesium and renders it void. Supplementing won’t be enough, must detoxify the metals.
• Aluminum – Antacids/Anti-perspirants/Cosmetics – aluminum foil – aluminum penetrates the blood brain barrier and is very difficult to detoxify. Impedes the utilization of calcium/magnesium/phosphorous. Neutralizes pepsin.

• Lead – binds with calcium and makes it unusable for the body.

Also an excess of certain minerals in the body can antagonize other minerals and cause depletion. For example, excess sodium depletes potassium. Excess calcium depletes magnesium by dominating over it. Too much of one will dominate the other. Iron and copper need to be in the right proportion and work together. They are co-factors. Potassium deficiency it’s not enough to just take potassium, you also need magnesium. Potassium inside the cell needs magnesium to maintain it. Copper/zinc – copper tells the body to retain estrogen. Copper toxicity is commonly known in hyperactive violent individuals. It is a primary cause of miscarriages and susceptibility to postpartum depression.

What To Do If You Are Mineral Deficient

Gain an in-depth picture into your overall health >> Yes, tell me more!

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7/8/2016 Factors That Deplete Minerals in the Body

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Supplementation with minerals is not a simple solution. It is not enough to supplement with one mineral to fix a specific deficiency, though for short periods of time with extreme symptoms it can certainly be helpful. But, knowing how to approach this can be tricky. I personally suggest working with someone qualified to help you balance your minerals safely if you are looking to supplement. Not only will minerals need to be considered but underlying issues as to why you may not be utilizing the minerals you are getting in the first place. It’s important to work with someone so you do not take too much of one and throw off your balance of another or become toxic.

It’s not enough to test the blood to find out the body’s mineral status. I can recall iron being a widely recognized deficiency. Back when I was in my early twenties I often showed signs of being anemic. The Dr. would then put me on iron pills and retest my blood and sure enough, it would show my iron levels were back up. But in reality anemia only counts for 1/3 of the problems caused by iron deficiency. Those were never addressed. Not only that, but if one is lacking in iron they are typically also low in other vitamins that work synergistically with iron. It is rare that a single mineral deficiency will develop. This is why supplementing with just iron, or just magnesium is not a good approach. Also, you can’t just take a pill and address all the issues related to an ‘iron deficiency’. You have to understand that the body can only utilize iron if the stomach is acid enough to absorb it in the first place. Also, iron can hide itself in the body when a bacterial infection is present, so it won’t show up in blood tests. This is just one example of the issues surrounding one specific mineral and why it is not wise to haphazardly supplement with any individual mineral alone, or without knowing all the cofactors involved.

The best way to ensure you are getting a wide array of minerals is by a whole foods, properly prepared nutrient dense diet OR SIMPLY USING MOMATOMIX!!!! Understanding traditional foods and what our ancestors and indigenous tribes and cultures ate throughout history can really help us in our modern day peril of industrialized processed foods and depleted soils. It is critical in my opinion to learn how to make mineral rich bone broth and consume it regularly. This is one of the absolute best options and most absorbable forms available to us. Mineral rich salts are another great source. Our water used to be the best source, but nowadays our waters are so polluted that is not the best option anymore. Following the dietary principles as taught in; Nourishing Traditions, Traditional Foods Our Bodies Best Medicine, Deep Nutrition, Real Food: What to Eat and Why, The Primal Blueprint, The Primal Blueprint Cookbook, Primal Body Primal Mind, Eat Naked, The Paleo Solution, Super Nutrition For Babies, along with Dr. Natasha’s GAPS dietary protocol will ensure that you have the right raw ingredients to work with.

Consider getting support from a holistic practitioner/nutritionist that understands these dietary principles. Also consider getting hair tissue mineral analysis to assess your mineral levels, especially if you have health conditions that won’t resolve after following a good diet protocol for any length of time. You may have some foundational things that need to be worked on that you are not aware of. Diet does usually help health issues resolve, but when it doesn’t typically there is need for supplemental therapy or even further work that you will need guidance with.

 

 

W H A T  I S  M O M A T O M I X ? 

Same ole MOMATOMIX packed with even MOOR Green Healing Power than ever before!!!! Its the same Green Mix of Nettles & Dandelion however I have now added:

Alfalfa

Dulse

Red Raspberry

Yellow Dock

Bupleurum (Bupleurum Chinense)

Licorice (Glycyrrhiza Glabra)

Milk Thistle (Silybum Marianum)

Organic Mustard (Sinapis Alba)

Black Radish (Raphanus Sativus Niger)

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Plant Enzyme & Alkaloid MATRIX

Chlorella (Chlorella Vulgaris)

Organic Wild Lettuce (Lactuca Virosa)

Kelp

Kale

Red Cabbage

Bell Peppers

Cucumber

Celery

Asparagus

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Amaranth Sprouts

Quinoa Sprouts

Brussell Sprouts

Millet Sprouts

Parsley

Adzuki Bean Sprouts

Pumpkin Seed Sprouts

Chia Seed Sprouts

Kamut

Not to Mention all the other familiar players you already now from the Original MOMATOMIX ie… Stabilized Oxygen, Every Essential Amino Acid, Every PGM Monatomic Mineral (including Gold, Platinum, Irridium, Ruthenium, Rhodium etc…),

 iridium

Heavy Hydrogen, Every Ionic Mineral & Every Colloidal Mineral the Body requires

Swadj Momatomix.001

Heavy Hydrogen (Deuterium) in Living Organisms May Provide Clues to Prevent and Treat Cancer

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Monday, 15 June 2015 13:30 (UTC + 2)
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Budapest, Hungary, June 15, 2015 / B3C newswire / — Sub-molecular cellular events, driven by hydrogen’s replacements with deuterium, explain medical and economical failures of targeted molecular cancer drugs, which are the main conclusions of the 3rd International Congress on Deuterium Depletion held in Budapest, Hungary, in May 2015.  The Hungarian Nobel-prize winning scientist Albert Szent-Györgyi envisioned cancer cures that go beyond large molecules including genes and proteins, but rather target sub-molecular mechanisms, where the electrons play a role.  Dr. Gábor Somlyai, Hungarian “sub-molecular” biologist, had begun investigations in 1990 regarding naturally occurring deuterium (D; heavy hydrogen (H)) as the cause of cancer.  Results presented at the meeting clearly show that the D/H ratio in cellular water pools and the transfer of their deuterium content to different structural and functional molecules via reductive synthesis are essential for maintaining normal cellular functions, DNA and protein integrity.  Pharmaceutical manufacturing of deuterium depleted nutritional products, including deuterium-depleted water, the proprietary procedure established by HYD LLC for Cancer Research & Drug Development, has broad potentials to enhance the effectiveness of current oncotherapies, as well as to innovate new ones.

The pharmaceutical industry has been seeking magic bullets to target specific genes and gene products, which continue to produce significant medical and economical challenges via drug failures, narrow range of responders, anecdotal cures claiming false evidence, poor quality of life from severe compound toxicities with enormous and unsustainable treatment costs.  Gábor Somlyai PhD, Hungarian molecular biologist, was the first who recognized the biological importance of heavy hydrogen, i.e. deuterium, which can replace hydrogens due to its high concentrations in hydrogen bonding networks with undesired consequences that affect DNA stability in mammalian cells.

In the early nineties, Gábor Somlyai, PhD, recognized that the shortage of this isotope in deuterium-depleted water (DDW) sensitized tumors to withdraw from repeated cell cycles and decreased their proliferation.  Depletion of deuterium also induces changes in metabolism and gene expression, which are claimed to affect cancer outcomes using targeted therapies.  The 3rd International Congress on Deuterium Depletion focused on the latest advances in research and clinical applications of deuterium depletion, its present and future role as anticancer, diabetes and neurological therapies (all lectures and interviews are available at www.deuteriumdepletion.com).  Lead scientists from the USA, France, Spain, United Kingdom, Russia, Sweden and Hungary presented results of cutting-edge international research efforts.  Gábor Somlyai, head scientist of HYD, LLC, presented a 3 to 9 fold increase of the median survival time (MST) upon DDW administration in almost 2,000 cancer patients, applied in combination with conventional therapies in prospective and retrospective studies.  László G. Boros, professor at UCLA, presented biochemical groundwork related to deuterium depletion as the natural cancer preventing function of properly working mitochondria, which are responsible for producing deuterium-depleted metabolic water to prevent epigenetic events that cause cancer.  It is well known that mitochondrial functions are damaged in all cancer cells, and the lack of metabolic water recycling may be the underlying cause of uncontrolled growth of tumor cells.  Dominic D’Agostino (University of South Florida) talked about the use of ketogenic diet and experimental hyperbaric oxygen treatment in various cancer models, which offer therapeutic benefits in ongoing clinical trials in the US, consistent with the increased production of deuterium-depleted metabolic water to treat cancer.  HYD, LLC also proved that different feedstuffs, altered in their deuterium content, determine overall cellular functions as the common sub-molecular biological phenomenon and key mechanism to explain natural and pharmacological deuterium depleting processes in healthy mitochondria or therapeutic deuterium depletion in cellular water.

HYD LLC for Cancer Research and Drug Development and its parent company, HYD Pharma Inc, completed the first facility in the world able to produce deuterium-depleted water (DDW) according to GMP rules, and having the completed protocol in hand will apply for ethical approval to start Phase 2 clinical trial. In 2015 the first patients will be recruited.
About HYD LLC for Cancer Research and Drug Development
HYD LLC was established in 1992 for the development and worlwide marketing of drugs and consumer products, that utilize the proprietary procedure, deuterium depletion. Since 1993, the company has been pioneering in research and drug development related to deuterium depletion, and was worldwide the first to investigate the biological role and physiological importance of naturally occurring deuterium. The company’s mission is to develop and register novel pharmaceutical and consumers products primarily for the treatment and prevention of tumorous diseases, and to open up new ways of application of the method in further ranges of indication. The first anticancer drug based on deuterium depletion (Vetera-DDW-25® A.U.V.) was registered by HYD LLC for veterinary use in 1999. Vetera-DDW-25 has been effective in combination with surgery or as a single treatment. Mammary tumors in dogs and cats showed a response rate higher than 70%; more than 50% of the animals achieved complete recovery. In 2012, Primus Capital closed a USD 2 Million investment in HYD Pharma Inc. The investment is being used for validation of research results, and for implementation of a new human phase II clinical test.


Contact

Dr. Gábor Somlyai
CEO
HYD LLC for Cancer Research and Drug Development
Phone: +36 1/ 365-1660
Fax: +36 1/365-1661
E-mail: gsomlyai@hyd.hu

For centuries mankind has sought the secret of a long and healthy life.

And for centuries it seems we were looking in the wrong place. Forget exotic pills and potions, the key to prolonged life could be as simple as a glass of water. Scientists believe ‘heavy water’ enriched with a rare form of hydrogen could add as much as ten years to life.

And by also modifying foods, such as steak and eggs, with the hydrogen the way could be cleared to allowing us to eat and drink our way to a healthy old age.

The idea is the brainchild of Mikhail Shchepinov, a former Oxford University scientist.

Young woman drinking glass of water

Elixir of life: ‘Heavy’ water could increase your lifespan by 10 years, say scientists

It centres on fortifying the body’s tissues and cells against attack and decay caused by free radicals, dangerous chemicals produced when food is turned into energy. Such ‘attacks’ on proteins are particularly damaging and have been linked to cancer, Alzheimer’s and Parkinson’s.

Dr Shchepinov’s theory is based on deuterium, a naturally-occurring isotope, or form of hydrogen, that strengthens the bonds in between and around the body’s cells, making them less vulnerable to attack.

He found that water enriched with deuterium, which is twice as heavy as normal hydrogen, extends the lifespan of worms by 10 per cent. And fruitflies fed the ‘water of life’ lived up to 30 per cent longer.

He now believes people could also benefit from the sweet-tasting water, or from deuterium-enriched ‘heavy foods’.

CLICK THE LINK BELOW FOR MOOR INFORMATION ON HYDROGEN IN WATER:

Hydrogen, Heavy Hydrogen & Structured Water by Minister EnQi & the God Complex Course Student Body

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Foods could be created by either directly supplementing them with deuterium or by enriching the feed of farm animals, this week’s New Scientist reports. Dr Shchepinov said recently: ‘We don’t have to be consuming isotopes as white powder.

If you take a pig and feed these things to a pig, all you need to do is consume the pig in normal fashion.’

The technology was likely to be tested in pet food first, he added. Dr Shchepinov runs biotech firm Retrotope whose scientific advisers include Aubrey de Grey, a controversial ageing guru.

Dr de Grey, a ‘bio-gerontologist’ who leads the Methuselah Foundation, a charity which aims for ‘the defeat of age-related disease and the indefinite extension of the healthy human lifespan’, said the research was ‘extremely promising’.

He said deuterium existed in all living matter at a certain level and it was a case of introducing it in a ‘more targeted manner’. There was no radiation involved, he added.

Dr Judith Campisi, of the Buck Institute for Age Research in California, said: ‘I’ve heard some pretty crazy ideas about how we might live longer but I’m intrigued by this.’

But Tom Kirkwood, of Newcastle University, said: ‘Shchepinov’s idea is interesting but . . . the history in the field is cluttered with hypotheses which are only partially supported by the data.’

https://www.youtube.com/watch?v=sfUKFxAgVZg

O X Y G E N

What is oxygen?

Air is a mixture of gases. Oxygen and nitrogen are the two main gases in the air we breathe. Oxygen accounts for about 21% of gas in air. The abbreviation for oxygen is O2. Every cell in our body needs oxygen to live. In order for oxygen to get to these cells, it must be transported through the airways of the lungs. If there is a blockage in the airways from mucus or narrowing of the airways from swelling or constriction, air may not reach enough alveoli to deliver oxygen. In some COPD patients, adequate air is brought into the alveoli, but the oxygen contained in the air is not able to pass into the capillaries surrounding the alveoli. This results in low oxygen levels and is called hypoxemia. By breathing even small amounts of additional oxygen, the oxygen level in the air rises above 21% to 23 or 24%. This small amount is enough to help “push” the oxygen into the capillaries. Since the body cannot store oxygen, oxygen needs to be given whenever the body is low on oxygen. In some instances, this means that the COPD patient must use oxygen 24 hours a day. The need for continuous oxygen is called long term oxygen therapy (LTOT). Oxygen therapy is important to understand because oxygen is not useful for everyone with COPD. In fact, oxygen is probably one of the least understood and misused therapies for people with COPD.

How do I know I need oxygen?

The need for oxygen is found by measuring the amount of oxygen in your blood stream. If your oxygen level is below a critical level at rest, then you need oxygen close to 24 hours a day. Some people with COPD do not need oxygen when they are inactive, such as when sitting, but need oxygen when exercising, such as walking, or with eating and/or sleeping. Breathlessness is not a reliable way of determining if you need oxygen. Sometimes, you can be very short of breath and not need oxygen; other times your breathing may feel okay, but you are not getting enough oxygen. Oxygen is not given to treat breathlessness. Although some patients feel some relief in their breathlessness from the flow of oxygen on their face, less expensive ways of getting this same relief can be obtained with a fan.

Your healthcare provider will find out if you need oxygen therapy by taking a blood sample from your artery. This test is called an arterial blood gas (ABG) and it measures carbon dioxide and pH in addition to oxygen. This can be done in the office, clinic or hospital, wherever the arterial blood equipment is available. When making an important decision, such as who needs oxygen, the best evaluation is with an ABG. Measuring oxygen levels can also be done with a pulse oximeter. Oximetry is performed by attaching a clip to your finger that shines a light through it. A tiny computer in the oximeter then determines your oxygen level by the color of the light that shines through from the other side. Oximetry only measures one characteristic of the oxygen in your body and, since it is not as precise as an ABG, should only be used as a guide to oxygen therapy.

How much oxygen should I take?

Oxygen is a medication prescribed by your healthcare provider. Optimally, the amount is carefully decided based on an ABG and then guided by oximetry. Once the amount of oxygen you need is decided, your provider will advise you of the rate at which the oxygen should be set. It is very important that you only use the amount that your doctor or nurse has prescribed, no more or no less. The treatment goal is to keep your oxygen at a level that meets your body’s need for oxygen, usually above 89%. Taking too much oxygen sends a message to your brain to slow your breathing. Whereas too little may deprive the tissue in your brain and heart of oxygen and result in memory loss or changes in your heart.

How many hours a day will I need oxygen?

In some cases, you may only need to use oxygen when you are exercising or sleeping. However, in most cases, oxygen should be used as close to 24 hours a day as possible. If your oxygen level is found to be low, using less than 15 hours a day has not been shown to provide a benefit, and does not protect your heart, brain and other organs of the body. If you are instructed to use continuous oxygen and choose to go off oxygen temporarily, it is best to do so only while resting quietly, not while sleeping, walking or exerting yourself.

During exercise you use more energy and therefore need more oxygen. To find out how much oxygen is needed during exercise, an exercise stress test or a timed walk test is usually done. It is important that the test be performed while using the type of delivery device that is going to be used at home.

The immediate benefits of using oxygen during exercise may be relief of breathlessness (also called dyspnea) and an improvement in your ability to walk or do activities.

Will I need oxygen when I sleep?

During sleep, you slow down your breathing. People have low oxygen levels while awake are usually also lacking oxygen during sleep. In some cases, people that may not require oxygen while awake may require extra oxygen while sleeping. Your healthcare provider will determine if and how much oxygen you should take at night. Your needs may be determined by using an oximeter that will record your oxygen level while you sleep in your home or you may be asked to sleep at a sleep laboratory.

What kind of devices provide oxygen?

There are several types of oxygen devices. The type of device you are given will depend on where you live and on the purpose of your oxygen. Oxygen can be delivered by three types of devices: oxygen concentrator, liquid system or oxygen in a metal cylinder.

What are oxygen concentrators?
 A concentrator draws in air from the room/environment (which contains 21% oxygen) and passes the air through a special filter collecting only the oxygen into a reservoir. When the machine is turned on, this process of collection takes place. The reservoir and the concentrator have limited storage, so virtually all the oxygen saved is released into the oxygen tubing for delivery to the patient. The concentration of oxygen delivered by a concentrator is 90-95%. The concentrator is run by electricity. The concentrator weighs about 50 pounds (23 kg) and is usually on wheels so that it can be easily moved in the home from room to room. The machine should be located where there is good circulation and away from furniture and walls. There is a compressor inside the machine that makes a regular noise that can be distracting to some. The device is not intended to be portable, however, recently, a new type of concentrator has been developed that makes it possible to fill portable cylinders from a concentrator. Also in development is a concentrator that weighs less than 10 pounds (5 kg) and runs off of a battery.

What maintenance do oxygen concentrators require?
Concentrators have an air inlet and a filter in front of the air inlet. Make sure that the air inlet is not covered and that it allows fresh air into the concentrator. This filter should be washed once a week in dishwasher detergent. After washing it should be thoroughly rinsed and completely dried before re-inserting. The instruction manual will outline how many filters your concentrator has and how often each of these should be changed. Your concentrator should be serviced after approximately 10,000 hours of use or annually. At that time it should be checked to assure that it is producing the right amount of oxygen. Improper maintenance may result in low concentrations of oxygen being delivered.

What is liquid oxygen?
Liquid oxygen is oxygen that is cooled to -183° C (-297°F), at which point it becomes a liquid. When in liquid form, the oxygen takes up much less room and can be stored in specially designed containers. The concentration of oxygen delivered from liquid oxygen is 100%.  Most hospitals use oxygen in liquid form. The gas molecules in the container are in constant movement, allowing for the liquid to slowly turn into a gaseous form. This results in a build up of pressure in the container, which is either delivered to the patient or released by a ventilation valve. Liquid oxygen is stored in the home in large storage reservoirs. The patient uses a smaller tank to fill for portability. You will need to be instructed on how to fill the smaller tank from the larger storage tank. Your oxygen delivery service will routinely fill the larger tank, every 1-2 weeks, depending on the flow rate you use.

What maintenance do liquid oxygen devices require?
The stationary tank should be placed on a level surface so there is minimal chance of the tank tipping. Little maintenance is required. If a bottle is attached to the tank for collecting condensed water, it must be emptied and cleaned regularly. The outside of the tank can be cleaned with a damp cloth when necessary. In addition to instructions for transferring the oxygen from the large tank to the smaller tank, instruction should be received in what should be done if any part of the system should freeze.

What are oxygen cylinders?
 This is the oldest method for delivering oxygen. Oxygen is compressed into a steel cylinder under high pressure, often a pressure of about 200 atmospheres. Like liquid oxygen, the concentration of oxygen delivered from cylinders is 100%. Oxygen is stored in large or small cylinders. Large cylinders are very heavy and have to be changed often as the contents are quickly used. Smaller cylinders are therefore emptied more quickly than larger cylinders, but are portable. Smaller aluminum cylinders are also available for portability. When using oxygen-sparing tubes or oxygen-conserving devices, these small cylinders can last for up to 8 hours. The small cylinders are usually used for portability when an oxygen concentrator is the main source of oxygen in the home.

What maintenance do oxygen cylinders require?
The pressure valves must be checked frequently. When the cylinders are empty, the regulator must be removed and placed on a full cylinder.

What about hoses or tubes attached to the oxygen device?

The main tubing attached to the different systems can be up to 15 meters/50 feet long to allow for mobility. The length of the tubing should only be as long as necessary in order to be mobile, for example long enough to get from one end of the house to the other. Having excess tubing may become a hazard to yourself and others. Long tubing also increases chances of knotting and cutting off the flow of oxygen. The tubes should be changed every 6-12 months. The tubing must be the right dimension. The inner diameter should be at least 5 mm to ensure the resistance is minimal.

What is a nasal cannula?
A nasal cannula is a dual-pronged tube attached to the oxygen device for delivering oxygen through the nose. These tubes come in different sizes and lengths. Make sure that the one you have fits you well. The typical length of the tubing is about 2 meters (6 feet). The nasal cannula should be changed approximately once a month due to the plastic nasal cannula becoming hard and stiff. The part of the cannula that is situated in the nose may be washed and the rest of the cannula may be wiped with a damp cloth.

What are oxygen sparing/conserving devices?
Oxygen-sparing/conserving devices are devices used to reduce the amount of oxygen needed from the oxygen source (liquid, concentrator or cylinder). These devices improve the efficiency of the delivery of oxygen, reducing the amount of oxygen that is used. This is accomplished by increasing the flow of oxygen on inhalation and limiting the flow of oxygen on exhalation. By increasing the delivery of oxygen when you breathe in, and reducing or stopping the delivery when you are breathing out, less of the oxygen is wasted. This makes it possible to use smaller and lighter ambulatory systems or standard systems. In addition, the delivery systems (liquid or cylinders) last longer. There are three types of oxygen-sparing/conserving devices: the on-demand device, reservoir cannula and transtracheal oxygen.

What is an on-demand device?
On-demand oxygen delivery devices deliver a small amount of oxygen, usually when you begin to take a breath in through your nose. The delivery device is connected to the oxygen source by the nasal cannula. The device senses the start of inhalation (through the nasal cannula) and immediately gives a short pulse of oxygen.

Nose congestion and mouth breathing may make it hard for the delivery device to sense inhalation. If the level of inspiration through the nose is very low, no oxygen may be delivered. Some types of devices have an alarm that goes off if no breathing activity is detected. Most of the on-demand devices are battery driven and the batteries need to be replaced every couple of weeks.

What are reservoir cannulas?
A reservoir cannula operates by storing oxygen in a small chamber. Storage of oxygen takes place while you are breathing out. This stored oxygen is available when you breathe in. This may allow you to require lower oxygen flow rates while still receiving the same amount of oxygen. There are two types of reservoir devices, the Oxymizer and the Pendant Oxymizer. The differences in the two devices are the location where the storage chamber is located.

What is transtracheal oxygen?
Transtracheal oxygen is oxygen delivered through a catheter placed directly through the neck into the trachea (windpipe). Delivery of oxygen directly into the trachea provides higher amounts of oxygen to be delivered because little is wasted. Flow rates of oxygen can often be reduced by close to 50% at rest and 30% during exercise, as compared with oxygen delivered via a standard nasal cannula. A cosmetic advantage of transtracheal oxygen therapy is that the tubing is not as visible as with standard devices.

Not everyone is a candidate for transtracheal oxygen delivery (TTOD). Candidates must be evaluated, educated and monitored by a trained team of healthcare providers. Complications from TTOD are not frequent, but can be serious.

Do I need a humidifier on my oxygen system?

If you use transtracheal oxygen, humidification of the oxygen is important. With other delivery systems at less than 4 liters per minute, humidification is not usually necessary or beneficial. If you have dryness in your nose, you can use a saline (salt water) spray. If this does not help, a humidifier can be attached to the oxygen system. The humidifier is a bottle filled with sterile or distilled water. The oxygen passes through the water to gather moisture. Water from the humidifier should be changed every 1-2 days.

What should I watch for while I am on oxygen?

In some cases too much oxygen may lead to an increase of carbon dioxide in your blood. This can give symptoms like drowsiness and difficulty keeping awake. Receiving too much oxygen while sleeping can also result in a morning headache. A sign of receiving too little oxygen is a general feeling of fatigue. If any of these problems occur, contact your healthcare provider.

What safety precautions should I use when on oxygen?

Oxygen used properly is safe. DO NOT SMOKE NEAR OXYGEN! Also, stay away from open flames. It is important that no oil or grease is used on any of the oxygen equipment. Oxygen cylinders should be secured and placed in an area where they will not fall. Cylinders are under high pressure and a crack in the cylinder can be lethal. Remember to turn off all equipment when not in use. Oxygen containers should not be stored near water heaters, furnaces, or other sources of heat or flame. Oxygen containers and the storage room should be properly marked/labeled. There should be good ventilation around oxygen equipment. Your oxygen supplier should provide you with a complete list of instructions and safety precautions.

Do I have to worry about oxygen exploding or burning?

  • Oxygen alone will not explode and does not burn but oxygen will feed a flame.
  • Keep oxygen at least 2 meters or 6 feet away from an open flame.
  • Do not smoke while using oxygen, as clothing and hair can easily be ignited.
  • Stabilize all cylinders by placing carts in a safe area or by securing them to a wall.

In case of an accident what should I do?

In case of fire, evacuate immediately. Contact the fire department. Understand your oxygen system and what you need to do if there is a problem. Also, you should always have emergency telephone numbers in a central location, such as on the refrigerator. Emergency numbers should include 911 (or country code), your healthcare provider and your oxygen supplier.

Can I travel with oxygen?

It is safe to travel with oxygen, however, various transports have different regulations about their use with oxygen. Contact the appropriate business (airport, boat, train, bus) about their regulations well in advance of travel. Make sure that you have plenty of oxygen with you in case of delays or emergencies. Carry the contact numbers of your healthcare provider and oxygen supplier; you never know when you might need them. General information is listed below. More specific information on traveling with oxygen is available at www.oxygen4travel.com.

When traveling by car, oxygen equipment must be fastened securely in an upright position so that the equipment is stable during the trip.

When traveling by boat, ferry, train or bus take the same considerations as traveling by car. Contact the boat, ferry, train or bus company a few weeks before traveling to find out which rules apply.

When traveling by plane you should plan your trip weeks in advance and inform the airline and check their regulations. Obtain an oxygen prescription from your doctor that provides your diagnosis, your present condition, a statement that it is safe for you to travel and your oxygen prescription. Your oxygen company can help to arrange for oxygen at the airport and travel destinations. You should book a direct flight for several reasons: some airlines charge for oxygen by each leg of the trip, you will be off oxygen during part of your layover and travel is much less tiring when you do not have to make a connection. Make sure you keep a copy of your oxygen prescription, medication prescriptions, know the health facilities and healthcare providers at each travel destination, and take extra medicines on the plane with you, Your oxygen company can be a great source of help for travel.

ALL THAT OR DO I JUST GRAB A BOTTLE OF MOMATOMIX????

G O L D

A Brief History Of The Health Support Uses Of Gold

The earliest records of the use of gold for medicinal and healing purposes come from Alexandria, Egypt. Over 5,000 years ago, the Egyptians ingested gold for mental, bodily and spiritual purification. The ancients believed that gold in the body worked by stimulating the life force and raising the level of vibration on all levels.

The Alchemists of Alexandria developed an “elixir” made of liquid gold. They believed that gold was a mystical metal that represented the perfection of matter, and that its presence in the body would enliven, rejuvenate, and cure a multitude of diseases as well as restore youth and perfect health.

As many as 4,500 years ago, the Egyptians used gold in dentistry. Remarkable examples of its early use have been found by modern archaeologists. Still in favor today as an ideal material for dental work, approximately 13 tons of gold are used each year for crowns, bridges, inlays and dentures. Gold is ideal for these purposes because it is non-toxic, can be shaped easily, and never wears, corrodes or tarnishes.

In medieval Europe, gold-coated pills and “gold waters” were extremely popular. Alchemists mixed powdered gold into drinks to “comfort sore limbs,” which is one of the earliest references to arthritis.

During the Renaissance, Paracelsus (1493-1541) – who is considered the founder of modern pharmacology – developed many successful medicines from metallic minerals including gold. One of the greatest alchemists/chemists of all time, he founded the school of Iatrochemistry, the chemistry of medicine, which is the forerunner of pharmacology.

In the 1900s, surgeons would often implant a gold piece under the skin near an inflamed joint, such as a knee or elbow. As a result, the pain would often subside or cease altogether.

In China, the restorative properties of gold are still honored in rural villages, where peasants cook their rice with a gold coin to replenish the mineral in their bodies, and fancy Chinese restaurants put 24-karat gold-leaf in their food preparations.

Colloidal Gold

If metallic gold is divided into fine particles (sizes ranging from one to one hundred billionths of a meter) and the particles are permanently suspended in solution, the mineral becomes known asColloidal Gold and exhibits new properties due to the larger amount of gold surface area available.

Colloidal Gold was first prepared in a pure state in 1857 by the distinguished English chemist, Michael Faraday. Many uses were found for the amazing solutions of “activated gold.”

In the nineteenth century, Colloidal Gold was commonly used in the United States to cure alcoholism (then called dipsomania, defined as the uncontrollable craving for alcoholic liquors), and today it is used to reduce dependency on alcohol, caffeine, nicotine, and carbohydrates.

In the United States, as far back as 1885, gold had been known for its healing capabilities for the heart and improved blood circulation. And gold has been used to treat arthritis continuously since 1927.

Europeans have long been aware of the benefits of gold in the system and have been buying gold-coated pills and ‘Gold Water’ over the counter for well over 100 years.

In July of 1935, Clinical, Medicine & Surgery had an article entitled “Colloidal Gold in Inoperable Cancer” written by Edward H. Ochsner, M.D., B.S., F.A.C.S. which stated, “When the condition is hopeless, Colloidal Gold helps prolong life and makes life much more bearable, both to the patient and to those about them, because it shortens the period of terminal cachexia (general physical wasting and malnutrition usually associated with chronic disease) and greatly reduces pain and discomfort and the need of opiates (narcotics) in a majority of instances.”

Modern Uses

Today, medical uses of gold have expanded greatly. It is used in surgery to patch damaged blood vessels, nerves, bones, and membranes. It is also used in the treatment of several forms of cancer. Injection of microscopic gold pellets helps retard prostate cancer in men. Women with ovarian cancer are treated with colloidal gold, and gold vapor lasers help seek out and destroy cancerous cells without harming their healthy neighbors.

Every day, surgeons use gold instruments to clear coronary arteries, and gold -coated lasers give new life to patients with once inoperable heart conditions and tumors.

Gold has become an important biomedical tool for scientists studying why the body behaves as it does. By attaching a molecular marker to a microscopic piece of gold, scientists can follow its movement through the body. Because gold is readily visible under an electron microscope, scientists can now actually observe reactions in individual cells.

Some researchers are placing gold on DNA to study the hybrid genetic material in cells. Others are using it to determine how cells respond to toxins, heat and physical stress. Because it is biologically benign, biochemists use gold to form compounds with proteins to create new lifesaving drugs.Gold has been known down through the ages to have a direct effect on the activities of the heart, and helps to improve blood circulation. It is beneficial for rejuvenating sluggish organs, especially the brain and digestive system, and has been used in cases of glandular and nervous congestion and lack of coordination.

The body’s temperature stabilizing mechanism is restored to balance with gold, particularly in cases of chills, hot flashes, and night sweats.

Colloidal Gold has a balancing and harmonizing effect on all levels of body, mind, and spirit. It is used to improve mental attitude and emotional states.It has been reported to promote a feeling of increased energy, will power, mental focus and libido.

According to many studies, colloidal gold increases mental acuity and the ability to concentrate. Colloidal gold is thought to strengthen mental function by increasing the conductivity between nerve endings in the body and on the surface of the brain.

Gold is an all-natural mineral that is non-toxic and exhibits no interactions with other drugs, and is easily tolerated by the body.

The fabulous healing properties of gold are slowly but surely being rediscovered, as modern scientists and physicians uncover what the ancients seem to have known all along: That gold is indeed a very precious metal.

The Rich and Wealthy around the world are eating Gold like it is going out of style.

When you Google ‘why’ or ‘the health benefits of eating gold’, “Can the Human Body Digest Gold?” you only get one answer. “There are no health benefits from eating Gold. None, zip, zero. period.” End of answer.

“No. The human body cannot digest gold.”

“NO, NO,,NO!”

“No.”

“Not very well”

“Not completely”

“No.”

“No.”

But Google is such the lier. What they are doing is completely censoring the “real” reasons. Remember, if there is something google wants to hide, they just do it and present only one point of view. Many voices, one point of view.

YouTube, same thing. NO, NO NO NO. Except for this one single video below.
The rich are doing it all over the world, and there is only one positive video on YouTube about it.
Guess YouTube is a lier also. Of course, google owns youtube 🙂

We ran across a small series of articles or posts recently that stated:
“We are electrical beings. We operate by electrical signals being passed between cells in the brain and muscles.
If we had gold in us, (gold being the best electrical conductor on earth), we would think faster and better. We would be stronger and more agile. And this could also help us unlock the hidden and unused portions of our brain and unlock our unused ‘God D.N.A.’
Scientists call it ‘Junk DNA’).

‘God’ or ‘Junk’ DNA is the 75% of DNA all humans have which is completely inactive. Scientists really think it is DNA that was “turned off” and want to turn it back on, for the “Select People”. They tell the rest of us that it is nothing but ‘useless junk’.

We can get our own edible and completely digestible gold from Natural Unrefined Sea Salt, at 1 ppm (Parts Per Million).

***

For centuries, people from all over the world have been used to eating edible gold for its impressive effect, its inimitable aestheticism and its mystic properties.

Since medieval times, edible gold leaf in the form of flakes and dust has been used to embellish and decorate gourmet food. The Elizabethans created sumptuous banquets by adding edible gold to their table on fruits such as oranges, grapes, dates and figs. The Japanese have been adding edible gold to foods and even to their sake for centuries.

Edible Gold leaf is edible because gold is considered under this form of extraordinary fineness as a food colorant (E175) according to European standards.

***

As any private banker will tell you, the wealthy have become gold bugs. They are buying gold futures, gold bars, gold coins, just about anything made from the shiny stuff. It is the ultimate crisis bet: when the world is falling apart, gold will always retain value (that is the theory anyway).

Reuters
Serendipity-3′s the Frrrozen Haute Chocolate
The wealthy in Abu Dhabi have another way to enjoy gold: eating it. An article by Bradley Hope in the National says the Emirates Palace hotel served up five kilograms, or about 11 pounds, of edible gold to its dining guests in 2008. “That amounts to 5,000 one-gram bottles of gold leaf flakes from a German distributor, which each go for about $100,” the article states. The edible-gold budget for the Emirates Palace, which prides itself on its gold theme, could be as high as $500,000 a year.

The gold, in flake, powder or sheet form, is served up in everything from a rose champagne ($2,995 for a three-liter bottle) to chocolate cake and cappuccinos. The article says the Russians are especially avid consumers of gold, and like to eat it with their caviar and oysters.

Plenty of U.S. restaurants serve up gold to those who like to wear their bling on the inside. A New York chef came up with a $1,000 bagel featuring white truffle cream cheese and goji berry-infused Riesling jelly with golden leaves. An L.A. candy maker sells treats called Holiday Nougat, made with flakes of 23-karat edible gold leaf.

Stephen Bruce, owner of New York ice cream parlor Serendipity3 famously came up with the $25,000 Frozen Haute Chocolate sundae, covered in 23K edible gold-infused whipped cream. (The shop had to close for a while after the health department found rodents in the kitchen. Presumably even Manhattan mice also have developed a gilded palate.).

As much as these marketing gimmicks may have served their purpose during the shiny, happy boom times, they probably will lose their luster in the age of thrift. “A lot of people still ask why we use gold in food,” said Jean Pierre Garat, the head of food and beverage at the Emirates Palace. “We tell them it’s a sign of excellence.”

But who will want to eat a $3,000 bottle of excellence after their fortunes have crashed and their private jets are being repossessed? Maybe the ever-creative chefs of the world will come up with a more timely replacement. Perhaps iron shavings or finely layered sheets of 401K statements.

***

Jeff H Peterson, Material science and engineering PhD student and general knowledge enthusiast

4.8k Views
While monotonic gold may not have any health benefits, gold nanoparticles can be used to treat cancer.
http://www.sciencedirect.com/sci…
and
Laser-Activated Gene Silencing via Gold Nanoshell−siRNA Conjugates
and
Immuno Gold Nanocages with Tailored Optical Properties for Targeted Photothermal Destruction of Cancer Cells
Gold tends to absorb light energy and re-emit it as heat energy (infrared) quite easily (part of the reason it is gold in color). For certain types of cancer, gold nanoparticles have been used to selectively target tumor cells by first giving the patient a dose of gold nanoparticles and then shining a laser at the tumor area. The gold nanoparticles near the tumor heat up quite a bit and end up killing the tumor cells. With a combination of selective affinity (targeting the gold nanoparticles to specifically go towards the tumors) and advanced imaging techniques, this could be an extremely viable way to treat cancer in a way with many less side effects than traditional chemotherapy.

Ormus, also known as ORMEs, m-state elements, white powder gold, or the Philosopher’s Stone, was discovered in 1975 by an Arizona farmer named David Hudson. He discovered some material in his soil that he had never seen before. He laid it out to dry in the hot Arizona sun so he could have it analyzed. What happened next was absolutely remarkable: the stuff exploded in a big flash of light and disappeared! But when he dried it without the use of sunlight it didn’t disappear.

Hudson was a very successful farmer and businessman so he could afford to have an expensive assay of the material done by a professor at New York’s Cornell University. The stuff turned out to contain gold, silver, iron and aluminum, among other things. However, the gold and silver did not dissolve in fluid, as is usually the case. The iron and aluminum also did not dissolve in various acids and in their isolated form, they formed a strange black matter.

One by one the elements were isolated. Until the standard tests revealed there should be nothing left. But there was something left – a lot of it, in fact. The scientist told Hudson there was nothing, although after removal of the individual elements a staggering 98% of the material was still left! Hudson had spent a lot of money on the analyses and left the university completely disappointed in academic science.

Dissatisfied but determined, Hudson sought out a German expert who, together with him, was willing to analyze the stuff further and build special machinery to do this. The assays showed that it contained various precious elements such as platinum and variants thereof, like rhodium, iridium, ruthenium and osmium.

The tests also showed that this material reacted differently to various heat and cold treatments. The time period to which they exposed the stuff to hot or cold temperatures also produced different results. The turning point was at 70 seconds heat treatment. When Hudson stopped the process at 69 seconds the powder contained no precious elements, yet at 70 seconds or over it did.

Hudson then went to a specialist at the University of Iowa. They conducted several experiments and once again produced the most amazing results. The material expressions of the stuff magically changed depending on the degree of warming or cooling they subjected it to. Among these forms were a white powder but also glass. Elements such as iron spontaneously disappeared or morphed into other elements. The material also changed weight, particularly when exposed to air.

Hudson was advised to patent these elements to prevent others from using his findings and keep him from experimenting further. In March of 1988 Hudson patented these elements which he called Orbitally Rearranged Monoatomic Elements, or ORMEs. This has become known as Ormus and stands for what are twelve known elements which exist both in a material and an immaterial, energetic form.

Hudson found this out by getting in touch with one of the American pioneers of quantum physics, Hal Puthoff. Puthoff explained to him the strange phenomena associated with Ormus. Ormus elements are capable of losing their material form under the influence of warmth and sunlight, making them no longer subject to the laws of gravity and even capable of dissolving into sunlight. This is what Hudson had witnessed when he dried the material in the hot sun. The Ormus had literally become one with the light and transferred to another dimension in which there is no space-time. By cooling it down, he learned to bring back the stuff to the exact place where he had laid it to dry, back to the material world of space-time in which we live.

Ormus is a superconductor. These elements resonate with the primal energy, the zero point from which all life originates and which is a quantum potential of possibilities. Ormus is one with this endless source of energy, which can be found in the air, the soil, plants, stones and the sea. Hudson even showed by dissecting animal brains that they too contained Ormus. According to Hudson our brains contain at least 5% Ormus. This percentage can be raised considerably if we take in food and water with a high Ormus content.

It is exactly these foods that are so sadly lacking today. Hudson refers to Ormus as ‘the light of life’ and ‘the Spirit’. He claims it not only makes us more spiritual but that it’s capable of correcting DNA too. Now think of the experiments the alchemists carried out in which they tried to change metals into gold and made a white powder out of gold. The church persecuted, tortured and killed these people. What did they know that we’re not supposed to know? The ancient Egyptians also knew. Gold has always been the true money and has remained so to this day. But the true value of gold may well be medicinal and spiritual instead of material.

There are, unfortunately, dark and powerful forces at work which are trying to keep us from realizing our true potential, our true evolution to a higher consciousness. They are spreading death energy across the planet. They do so by controlling our food and money supply. They are the inventors of NPK agriculture, which is based on growing crops with a bare minimum of three elements: nitrogen (N), phosphorus (P) and potassium (K). This technique came out of the successes they had had in World War One with nitrogen bombs. Plants grown with NPK cannot survive in nature because she sends a ‘clean-up crew’ of insects and fungi to dispose of these weak organisms. That’s why the crops are ‘treated’ with pesticides, which in turn are a variation of nerve gas.

Thus an unnatural product is kept artificially alive using war chemistry. As a result, we develop a structural mineral (and therefore Ormus) deficiency and ingest dangerous toxins which mess with our hormonal and nervous system. The diseases caused by this are then ‘treated’ with even more war-based chemicals. Like chemo therapy, for instance, which is nothing more than a variation of mustard gas.

Genetic engineering of crops such as corn, cotton, canola and soy is done to alter the natural genetic blueprint of these crops so they can be patented. This is done by making the plant sick using a cancer or virus to penetrate the plant’s DNA. Animals don’t fare much better. Millions of cows, pigs and chickens are kept in circumstances which would normally cause the animals to drop dead on their feet. Yet with medication, growth hormones and synthetic minerals they are kept alive long enough to be sent to the slaughter house. This process happens so quickly that many animals are skinned alive. The suffering of these animals defies description and you end up with sick plants and animals and death energy on your plate. Is this the kind of ‘food’ you’d like to eat? Is it any wonder only 5% of the world population are free thinkers?

Experiments show that Ormus is most abundant in the sea. Not so strange when you consider that sea water covers 70% of the earth’s surface and is the primal soup of all life on this planet. All known and unknown minerals on this planet are concentrated in sea water.

Eat as many raw and untreated natural products from good soil and grown with love. Drink wild water from streams in forests that comes up on its own volition. Expose yourself to the healing powers of sunlight by gazing into the sun with your eyes closed and palms outstretched. Breathe in as much forest air and sea air as possible.

In short, expose yourself to as much Ormus as possible. These are the known Ormus elements:

* Cobalt

* Nickel

* Copper

* Ruthenium

* Rhodium

* Palladium

* Silver

* Osmium

* Iridium

* Platinum

* Gold

Those who want to know more about Ormus should check out Barry Carter’s webpage:

(http://www.subtleenergies.com/ormus/index.ht…)

Ormus is life energy. This is sorely needed as a counterweight to the death energy we are exposed to daily through our food, our drinking water, our ‘medicines’, electromagnetic fields and radioactivity due to the use of depleted uranium by a flourishing war industry. This negative energy keeps us sick and dumb.

But it doesn’t have to be like this. Remember that the force of life is always stronger than the force of death and darkness is merely the absence of light. All you need to do is surround yourself by the light. It’s all around and inside you.

 

S U B L I N G U A L

 

Sublingual, meaning literally ‘under the tongue’ refers to a method of administering substances via the mouth in such a way that the substances are rapidly absorbed via the blood vessels under the tongue rather than via the digestive tract. The route of absorption via the highly vascularised buccal mucosa allow the substances a more direct access to the blood circulation, thus providing direct systemic administration.

Medically, sublingual drug administration is applied in the field of cardiocascular drugs, steroids, some barbiturates and enzymes. It has been a developing field in the administration of many vitamins and minerals which are found to be readily and thoroughly absorbed by this method. Sublingually absorbed nutrition, which avoids exposure to the gastric system and liver, means direct nutritional benefits, particularly important for sufferers of gastro-intestinal difficulties such as ulcers, hyperactive gut, coeliac disease, those with compromised digestion, the elderly and invalids – the nutritional benefit is independent of gastro-intestinal influences.

Subligual process

Image of tongue

There is considerable evidence that most sublingual substances are absorbed by simple diffusion; the sublingual area acting rather like litmus paper, readily soaking up the substances. However, not all substances are permeable and accessible to the buccal mucosa. The mucosa functions primarily as a barrier – similar to skin[1]. But while it was once believed that the barrier of human skin was ‘impenetrable’ it is now recognised that the dermis is a good site for the absorption of many substances (eg, vitamins E & C creams; hormones; nicotine patches) and it is a growing field of endeavour. Similarly the buccal mucosa presents an ideal site for absorption. This potential continues to be explored for the administration of many drugs – providing many useful studies and a better understanding of the modus operandi – although the benefits of the less intrusive nutrition therapies have had little opportunity as yet to be as thoroughly researched.

One of the best known drugs used regularly with great success is Glyceryl Trinitrate[2] – a potent coronary vasodilator which is used for the rapid symptomatic relief of angina. It has been found impressively effective when administered sublingually; pharmacologically active after only 1 – 2 minutes. The administration via an aerosol spray was found to provide rapid relief of symptoms, with first-class metabolism. The extent of first-class metabolism when compared to the sublingual spray decreased to 48% with sublingual tablets and 28% with the oral dose[3]. Following sublingual administration, nitrate appears in plasma . . . concentrations can be maintained for 24 hours[4].

Sublingual Verapamil[5] (a calcium channel antagonist prescribed for the management of angina, hypertension and certain supraventricular arrythmias) was effective in controlling the ventricular rate in 7 symptomatic patients and rapidly appeared in the plasma following sublingual administration. Experiments with some analgesics showed a many-times more rapid absorption from the mouth than the less lipid-soluble morphine. Impressive absorption has been attained with sublingual administration of desoxycortisone acetate, morphine, captoprill, nifedipine and 17-B Oestradiol – interestingly, it has also been shown that the sublingual administration of 17-B Oestradiol requires only 1/4 of the oral dose.

The Mechanics of Sublingual Absorption

The absorption potential of the buccal mucosa is influenced by the lipid solubility and therefore the permeability of the solution (osmosis); the ionisation (pH); and the molecular weight of the substances. For example, absorption of some drugs via the buccal mucosa is shown to increase when carrier pH is lower (more acidic) and decrease with a lowering of pH (more alkaline).

The cells of the oral epithelium and epidermis are also capable of absorbing by endocytosis (the uptake of particles by a cell as if by hollowly wrapping itself around it. These engulfed particles are usually too large to diffuse through its wall). It is unlikely that this mechanism is used accross the entire stratified epithelium. It is also unlikely that active transport processes operate within the oral mucosa. However, it is believed that acidic stimulation of the salivary glands, with the accompanying vasodilation, facilitates absorption and uptake into the circulatory system.

The mouth is lined with a mucous membrane which is covered with squamous epithelium and contains mucous glands. The buccal mucosa are similar to the sublingual mucosal tissue.

The salivary glands consist of lobules of cells which secrete saliva through the salivary ducts into the mouth. The three pairs of salivary glands are the parotid, the submandibular and the sublingual which lies on the floor of the mouth. The more acid the taste, the greater the stimulation of salivary output; serving also to avoid potential harm to acid-sensitive tooth enamel by bathing the mouth in copious neutralising fluid. With stimulation of salivary secretion oxygen is consumed and vasodilator substances are produced; and the glandular blood flow increases, due to increased glandular metabolism.

The sublingual artery travels forward to the sublingual gland, it supplies the gland and branches to the neighbouring muscles and to the mucous membranes of the mouth, tongue and gums. Two symmetrical branches travel behind the jawbone under the tongue to meet and join at its tip. Another branch meets and anastomoses with the submental branches of the facial artery. The sublingual artery stems from the lingual artery – the body’s main blood supply to the tongue and the floor of the mouth – which arises from the external carotid artery. The proximity with the internal carotid artery allows fast access to its route supplying the greater part of the cerebral hemisphere.

Osmosis

In order for a nutrient to be effectively absorbed sublingually, it needs to be able to travel accross the buccal mucous membranes; by a process of diffusion known as osmosis which applies to all forms of absorption by the body; governing both intestinal and sublingual absorption. The distribution of water accross cell walls depends on the osmotic difference in the blood between the intracellular and extracellular fluid. The distribution of water across blood vessel walls is determined by the in-vivo osmotic pressure of plasma and the total outward hydrostatic pressure. Unlike the cell membrane, the capillary wall is freely and rapidly permeable to small molecules. The diffusion of water accross a membrane that is only permeable to water depends on the molecular weight of the particle. Small particles that readily dissolve in water, rarely present a problem in permeation and diffusion, and so are able to move freely between the tissues of the body. Active transportation into cells leads to rapid metabolisation of the substances. Molecules such as glucose (fructose) and amino acids are essential for cell metabolism and special mechanisms have evolved to facilitate their rapid diffusion and permeation accross cell membranes.

The Water of Life

Water is physiologically the most important component of the body; it is the medium in which all of the physiological activities neccessary for life take place. The properties of water greatly influence the digestion and absorption of lipids. Water molecules strongly attract each other because of the asymmetrical distribution of electrons within each molecule; the area of the oxygen atom has many electrons and hydrogen atoms have few electrons. Water is the major component of both the the interior of the cell and the extracellular fluid that surrounds the cell. A little over half the body water is inside cells. About 15 – 20% of the extracellular water is in the plasma. The remainder is held in the extravascular, extracellular and interstitial fluid.

Water is an excellent solvent. Because it is such a good solvent, it is the most abundant molecule of the body; most other molecules in the body are dissolved within the water molecules. Water is also an excellent carrier of small particles and is very readily permeable: it is absorbed passively, by osmosis.

pH range

An acid is a substance that releases a hydrogen (H+ ) ion. The base is the substance that combines with it. The H+ concentration is usually shown using the pH scale; a scale of numbers which expresses the acidity/alkalinity of a solution.

At pH 7 the solution is neutral – the acidity and alkalinity are balanced. The lower the pH, the more acid and the higher the percentage of H+ ions.

Ascorbic Acid

Ascorbic acid is the major antioxident in the aqueous phase of the body. It is readily dissolved in water and its naturally acidic nature in aqueous solution provides a naturally low pH for rapid and efficient sublingual absorption of both itself as Vitamin C and the other solutes carried with it. Ascorbic acid readily dissolves in water.

Sublingual Nutrition

The advantages of sublingually administering nutrients seem to be manifold, offering improved bioavailability and more rapid metabolisation of the nutrients which are absorbed more fully. It allows individual control over the dosage for optimium benefit, within safe guidelines, and can allow absorption in a palatable and easily administered form, regardless of gastro-intestinal difficulties. It is especially useful for those who experience difficulty in swallowing tablets. Sublingual nutrients are available in readily dissolved tablets, or in fine powders, which are held under the tongue or in the mouth, until dissolved. Water soluble vitamins are passively absorbed, by osmosis, and the vitamin molecules are massed in the micelles for transport across the mucosal membranes.

Below is a Article from Pure Colloids…

We use the Highest Quality Ionic, Colloidal & Monatomic Gold in Swadj Momatomix

A Brief History Of The Health Support Uses Of Gold

The earliest records of the use of gold for medicinal and healing purposes come from Alexandria, Egypt. Over 5,000 years ago, the Egyptians ingested gold for mental, bodily and spiritual purification. The ancients believed that gold in the body worked by stimulating the life force and raising the level of vibration on all levels.

The Alchemists of Alexandria developed an “elixir” made of liquid gold. They believed that gold was a mystical metal that represented the perfection of matter, and that its presence in the body would enliven, rejuvenate, and cure a multitude of diseases as well as restore youth and perfect health.

As many as 4,500 years ago, the Egyptians used gold in dentistry. Remarkable examples of its early use have been found by modern archaeologists. Still in favor today as an ideal material for dental work, approximately 13 tons of gold are used each year for crowns, bridges, inlays and dentures. Gold is ideal for these purposes because it is non-toxic, can be shaped easily, and never wears, corrodes or tarnishes.

In medieval Europe, gold-coated pills and “gold waters” were extremely popular. Alchemists mixed powdered gold into drinks to “comfort sore limbs,” which is one of the earliest references to arthritis.

During the Renaissance, Paracelsus (1493-1541) – who is considered the founder of modern pharmacology – developed many successful medicines from metallic minerals including gold. One of the greatest alchemists/chemists of all time, he founded the school of Iatrochemistry, the chemistry of medicine, which is the forerunner of pharmacology.

In the 1900s, surgeons would often implant a gold piece under the skin near an inflamed joint, such as a knee or elbow. As a result, the pain would often subside or cease altogether.

In China, the restorative properties of gold are still honored in rural villages, where peasants cook their rice with a gold coin to replenish the mineral in their bodies, and fancy Chinese restaurants put 24-karat gold-leaf in their food preparations.

Colloidal Gold

If metallic gold is divided into fine particles (sizes ranging from one to one hundred billionths of a meter) and the particles are permanently suspended in solution, the mineral becomes known asColloidal Gold and exhibits new properties due to the larger amount of gold surface area available.

Colloidal Gold was first prepared in a pure state in 1857 by the distinguished English chemist, Michael Faraday. Many uses were found for the amazing solutions of “activated gold.”

In the nineteenth century, Colloidal Gold was commonly used in the United States to cure alcoholism (then called dipsomania, defined as the uncontrollable craving for alcoholic liquors), and today it is used to reduce dependency on alcohol, caffeine, nicotine, and carbohydrates.

In the United States, as far back as 1885, gold had been known for its healing capabilities for the heart and improved blood circulation. And gold has been used to treat arthritis continuously since 1927.

Europeans have long been aware of the benefits of gold in the system and have been buying gold-coated pills and ‘Gold Water’ over the counter for well over 100 years.

In July of 1935, Clinical, Medicine & Surgery had an article entitled “Colloidal Gold in Inoperable Cancer” written by Edward H. Ochsner, M.D., B.S., F.A.C.S. which stated, “When the condition is hopeless, Colloidal Gold helps prolong life and makes life much more bearable, both to the patient and to those about them, because it shortens the period of terminal cachexia (general physical wasting and malnutrition usually associated with chronic disease) and greatly reduces pain and discomfort and the need of opiates (narcotics) in a majority of instances.”

Modern Uses

Today, medical uses of gold have expanded greatly. It is used in surgery to patch damaged blood vessels, nerves, bones, and membranes. It is also used in the treatment of several forms of cancer. Injection of microscopic gold pellets helps retard prostate cancer in men. Women with ovarian cancer are treated with colloidal gold, and gold vapor lasers help seek out and destroy cancerous cells without harming their healthy neighbors.

Every day, surgeons use gold instruments to clear coronary arteries, and gold -coated lasers give new life to patients with once inoperable heart conditions and tumors.

Gold has become an important biomedical tool for scientists studying why the body behaves as it does. By attaching a molecular marker to a microscopic piece of gold, scientists can follow its movement through the body. Because gold is readily visible under an electron microscope, scientists can now actually observe reactions in individual cells.

Some researchers are placing gold on DNA to study the hybrid genetic material in cells. Others are using it to determine how cells respond to toxins, heat and physical stress. Because it is biologically benign, biochemists use gold to form compounds with proteins to create new lifesaving drugs.Gold has been known down through the ages to have a direct effect on the activities of the heart, and helps to improve blood circulation. It is beneficial for rejuvenating sluggish organs, especially the brain and digestive system, and has been used in cases of glandular and nervous congestion and lack of coordination.

The body’s temperature stabilizing mechanism is restored to balance with gold, particularly in cases of chills, hot flashes, and night sweats.

Colloidal Gold has a balancing and harmonizing effect on all levels of body, mind, and spirit. It is used to improve mental attitude and emotional states.It has been reported to promote a feeling of increased energy, will power, mental focus and libido.

According to many studies, colloidal gold increases mental acuity and the ability to concentrate. Colloidal gold is thought to strengthen mental function by increasing the conductivity between nerve endings in the body and on the surface of the brain.

Gold is an all-natural mineral that is non-toxic and exhibits no interactions with other drugs, and is easily tolerated by the body.

The fabulous healing properties of gold are slowly but surely being rediscovered, as modern scientists and physicians uncover what the ancients seem to have known all along: That gold is indeed a very precious metal.

There are many mysterious and magical things that have been recorded in history. The Biblical manna, the Philosopher’s Stone, the Fountain of Youth, Orgone energy, prana, chi, the Holy Grail, the Great Pyramid and the Ark of the Covenant are a few of these things. It looks like these things and more might be related to a new class of materials that have been identified and described in the last few decades.

In the late 1970s an Arizona farmer named David Hudson noticed some very strange materials as he was doing some gold mining on his land.  Hudson spent several million dollars over the following decade figuring out how to obtain and work with these strange materials. In 1989 David Hudson was granted patents on these materials and methods for obtaining them.(1)

Other researchers were also making similar discoveries around this same time but Hudson was the first to get information out to the public about his discoveries. During the early 1990s Hudson toured the United States giving lectures and workshops about what he had found. Transcripts of portions of three of David Hudson’s lectures are available on the Web. The most complete of these transcripts is the transcript of his Dallas lecture and workshop.(2)

The materials that David Hudson discovered appear to be related to the things I listed in the first paragraph of this article and to concepts of modern physics like superconductivity, quantum coherence and Bose-Einstein condensates.

These materials have been called ORMEs, monoatomic gold, white gold, white powder gold, ORMUS, m-state, AuM, microclusters, and manna. David Hudson calls the materials he found Orbitally Rearranged Monoatomic Elements or ORMEs.  He also refers to them as monoatomic elements in a high-spin state.

Since Hudson has patented his process for obtaining and identifying these elements, and since it has not been conclusively established whether these materials are monatomic or diatomic, it is recommended that the terms ORMUS and m-state be used when referring to these materials.

The ORMUS or m-state materials are thought to be the precious metal elements in a different atomic state.  The following elements have been identified in this different state of matter (these elements, with the exception of mercury, are listed in Hudson’s patents): 

 

KNOWN ORMUS ELEMENTS

Element

Atomic Number

Cobalt

27

Nickel

28

Copper

29

Ruthenium

44

Rhodium

45

Palladium

46

Silver

47

Osmium

76

Iridium

77

Platinum

78

Gold

79

Mercury

80

All of these m-state elements are quite abundant in seawater. They also seem to be present in most rock, fresh water and in the air. According to David Hudson’s research, these elements in their m-state may be as much as 10,000 times more abundant than their metallic counterparts.  There also may be other elements that occur naturally in the m-state.

Various researchers, working independently, have identified these materials in this different state of matter.  They have arrived at many of the same observations. These m-state elements have been observed to exhibit the quantum physical behaviors of superconductivity, superfluidity, Josephson tunneling and magnetic levitation.  It looks like these are an entirely new class of materials.

These m-state elements are also present in many biological systems. We believe that they may enhance energy flow along the acupuncture meridians and in the microtubules inside every living cell.(3)

It appears that this state of certain of these elements has been known throughout history.  Several of the procedures for extracting or making ORMUS have been adapted from ancient alchemical texts.  We believe that the Philosopher’s Stone and the Biblical manna may be variations on this state of matter.(4)

Some recommended alchemical texts related to the Philosopher’s Stone are “Sacred Science” by R.A. Schwaller De Lubicz and “Le Mystere des Cathedrales” by Fulcanelli. Another source is “Occult Chemistry” by Leadbeater and Besant. The premier treatise on the subject may be “The Secret Book” by Artephius(5)

There is evidence that the m-state elements are associated with the “dark matter” that astronomers look for in space, the Earth’s magnetic field, healthy soil, weather phenomena like lightning and that they are essential minerals for all life on Earth.(6) Certain properties of the m-state materials seem to be related to consciousness itself.(7)

A number of methods for obtaining the ORMUS elements have been devised in the last several years. The easiest of these methods is to raise the pH of clean ocean water to 10.78 and no higher, using lye water, then wash the resulting precipitate three times with distilled water.(8)

At this time, our knowledge of the nature of these materials and how to work with them is still at a very early stage. Any person with an interest in doing scientific work with them would most likely be able to make significant discoveries with a little effort. A number of email lists and local workgroups have been started to allow people to work together in this exciting field of discovery.(9)

It is my firm belief that, once it becomes widely known, the discovery of the ORMUS materials will be heralded as the greatest scientific discovery in human history.

David Radius Hudson is credited by most people in the field as being the originator of the term “Orbitally Rearranged Monoatomic Elements”, or by its acronym, the ORME.

 

Mr. Hudson began speaking publicly about his research and discoveries in 1995, when at that time he pointed out the multiple connections between the works of Zecharia Sitchin [1], the Anunnaki, the Tree of Life, The Egyptian Book of the Dead, Alchemy, Immanuel Velikovsky, Superconductivity, Ark of the Covenant, The Adam’s Family, and more recently the works of Laurence Gardner. [2]  There are also numerous researchers interested in a variation on the ORME, the ORMUS, where it is assumed that the working material is not necessary mono-atomic, but may be diatomic — consisting of two (or more) atoms of the precious metals.

The story of Mr. Hudson’s efforts over the years is given in the form of a rough transcript of his presentation in 1995 at the International Forum on New Science in Fort Collins, Colorado.  As such, it serves as an excellent introduction to the study of the ORME, and its immense implications.  His story and the profound revelations of his work are well worth considerable study.  This is only the beginning introduction.

DAVID HUDSON AT IFNS

I was buying gold and silver as an inflation hedge. Then got into producing gold from a natural source, old mining sources. Mining worked well with the farming. You beat Uncle Sam as much as possible out of taxes, and at the same time accumulate as much wealth as you can. Leaching gold with cyanide process is like leaching salt out in the farming process. More of a hobby than a business — no intention of making money. But something I enjoyed very much. Did it for fun.

In the process of recovering gold and silver, I began to recover something else, which was causing losses of the gold and silver. Eventually, it reached the point where the gold and silver would not recover at all because of the something else. I then shut it down, to find out what the problem material was. I am not a physicist or a chemist and had no idea what the stuff was. It would recover and had a specific gravity; it would recover in the molten lead like it was gold and silver; it would flow out of the lead; but when I held the lead down, I had nothing. The mining community refers to this as “ghost gold”, a non-assayable, non-identifiable form of gold.

I then became involved with someone who does emission spectroscopy (ES) and became aware of work done by the Soviet Academy of Sciences. When one does ES, it involves taking a carbon electrode, placing your sample on the carbon electrode, and then running a second carbon electrode down above it, and striking an arc. When you strike the arc, the elements ionize and give off specific light frequencies. This is spectroscopic analysis. In the analysis, it’s done for 10-15 seconds before the electrode is burned away, and American Spectroscopists claim that anything there will be ionized and read within those 15 minutes.

My sample was identified as Iron, Silicon, and Aluminum. I then spent three years in finding ways to take away all the Fe, Si, and Al. Then, I still had 98% of the sample of the material. On the arc, the material didn’t indicate to be anything. It was nothing. Back to Cornell University, where I worked with a Ph.D., who did X-Ray Analysis. This involved: Cumming Microscopy, Diffraction Microscopy, Fluorescent Microscopy, and five other wonderful technologies. The Ph.D. said that it was Iron, Silicon, and Aluminum. Stayed there to remove it all. After that, the Ph.D. said it was “pure nothing.” This wasn’t good enough for me. I could hold it in my hands, weigh it, perform chemistries with it — it was something. I then recalled that, according to the Soviet Academy of Sciences, the proper analytical tool is to burn the sample in the emission spectroscopic analysis for 300 seconds, not just 15.

To do this, you have to sheath the electrode with an inert gas — keeping all the oxygen away from the DC arc. Otherwise, the carbon oxidizes, and the electrode falls apart. I set up to do this, using Argon gas to sheath the electrode — keeping the oxygen away. Because carbon is a very high-temperature material, it will then last for 300 seconds. When the material was placed on the electrode and the arc was struck, there was no reading at all for 15 seconds [other than “electronic grass” on the scope, as well as Iron, Silicon, Aluminum, and occasionally, traces of Calcium]. Then the material went quiet.

[Argon gas if fundamentally crucial to Sonoluminescence, as well. It also has an identical crystalline structure to such elements as Rhodium and Iridium.]

Finally, after 90 seconds, Palladium (Pd) began to read; after 110 seconds, Platinum (Pt) began to read; at 130 seconds, Ruthenium (Ru); at about 140-150 seconds, Rhodium; at 190 seconds, Iridium; at 220 seconds, Osmium began to read. The Russians call this fractional vaporization. For example, when one has water in an iron container, you can’t get the iron hotter than the boiling point of water as long as there is water present. This is the basis for cooling systems in engines, and why automobile engines don’t overheat, as long as there is water present. But once, the water is gone, the temperature rises very rapidly to the melting temperature of the iron.

[The temperature of any well-mixed solution undergoing a phase change will stay at the temperature of the phase change until the phase is completed. Also, the relevant boiling temperatures for the metals in the sample are: Calcium: 1420 oC, Iron: 1535 oC, Silicon: 2355 oC, Aluminum: 2327 oC; followed by: Palladium: >2200 oC, Rhodium: 2500 oC, Ruthenium: 4150 oC, Platinum: 4300 oC, Iridium: >4800 oC, Osmium: >5300 oC. (Silver has a boiling point of 1950 oC, while Gold’s boiling point is 2600 oC.)]

Essentially, all of the emissions from the elements were coming off in the sequence of their increasing boiling temperatures. The maximum temperature of the DC arc is, theoretically, in the center of the arc, 5450 to 5500 oC; while the sample was slightly away from the center. Thus, all the heat went into boiling off one element at a time, in the sequence of their boiling temperatures. They come off individually as if there is nothing else in the sample.

I continued to run the sample for 2 and a half years, comparing it to standard samples. The amazing thing is that commercially available samples of the precious metals, when placed in the emission spectroscopic DC arc, read within 15 seconds. (And they assume they’re reading it all.)

But then it goes quiet, until after 90 seconds, it starts to read again. About 85% of the reading occurs at the end. In effect, the people buying the commercially available samples and doing readings, are only doing about 15 to 20% of the sample. And they assume it’s everything. Short burn times don’t do the trick. They assume the standard, and yet this is not the correct standard.

Keep in mind that the Soviet Academy of Sciences, the most prestigious scientific body in the Soviet Union and Johnson-Mathewe-Inglehart produce all the precious metals in the world. The mining activity of the best deposit in the world in South Africa for six of these elements (Pd, Pt, Os, Ru, Ir, and Rh — i.e. no silver or gold) may yield only one-third of one ounce of the precious metals per ton of ore. They go a half mile down into the ground, following an 18-inch seam of material, to get 1/3 of 1 oz per ton of all the precious elements. No one else knows it’s there, and no one can analyze it. We, on the other hand, can derive and identify out of one ton of ore: 6-8 ounces of Palladium, 12-13 ounces of Platinum, 150 ounces of Osmium, 250 ounces of Ruthenium, 600 ounces of Iridium, and 1200 ounces of Rhodium!!

This was then confirmed by a highly respected chemist and spectroscopy, including all of the colors of the solutions being correct, all the oxidation potentials were correct, all of the physical properties were correct. An analytical chemist. Consider Rhodium. Rhodium produces a crimson, blood red colored salt. That is how it got its name, from the rose-colored salt, and the only element which produces this color. Very conspicuous.

When you precipitate Rhodium out of solution, you add bromide as the oxidizer, and then you do a neutralization of the acid, and the hydroxide precipitates out of the solution. You filter it, dry it, oxidize it, hydrogen reduce it, and you should have metal. (Standard procedure). But we neutralized the solution of the pure Rhodium, got a red brown dioxide, filtered that out, dried it, and heated it in a tube furnace under oxygen up to 850 degrees for an hour to dehydrate it, and we’d get this red brown dioxide. Then we put it back in the tube furnace and hydrogen reduce it to a gray powder, and then take the gray powder in a tube furnace at 1000 degrees under argon, and it turned snow white.

A commercial spectroscopic firm then analyzed three samples, and again picked up Iron, Aluminum, Silicon, and Calcium. There was no consistency between the three samples, which were all the same. The material was 99.9% pure Rhodium, in different stages of the processing.

The standards that are sold as labeled as RhCl3, when in reality they are Rh12Cl36. It still has metal-metal bonds. Even without the Chlorine, you still have the metal bonds, which are never lost. But if you take Rhodium to the monatomic state, you can end up with HRhCl4. Then when you take away the Chloride, you get HRh (Hydrogen Rhodide). A Rhodide is a -1, instead of a +1. The physical properties are more like an Iodide.

When gold is produced as a monatomic gold, it’s a forest green color. As a metal, it’s a yellow gold. No one has monatomic gold as a commercial product. Monatomic gold is much more powerful, as in a fuel cell. Boiling gold will never result in a monatomic gold. Gold has the 5d, 6s1 electron structure (the single s electron, like Sodium, Potassium, Hydrogen, and Lithium), and is thus explosively reactive. Except that in the case of gold, it’s gold reacting with gold.

But in the bowels of the earth, in the volcanoes, nature is producing monatomic gold. When it comes out, 98% of the gold coming out is monoatomic, 2% is metal. [Thus, Hudson may not be making monatomic gold, he is separating it instead.] We have worked with the yellow gold, converting it, but always coming back to yellow gold. But when we get monatomic gold, it never goes back to yellow. And as monatomic gold, it is not metallic, has none of the metallic qualities of yellow gold.

If you use thermo-gravimetric analysis, and you produce monatomic gold, you get sort of a gray-black, Hydrogen Auride (HAu). When you heat it, and the proton is annealed away, this is the same way you produce Amorphous Silicon (Silane to Amorphous Silicon). When you heat it, the proton is annealed away, it goes to a snow white powder! It loses 4/9th of its weight. If you take it back to metal, it regains the weight. As you kept annealing the material, it would levitate – taking the pan with it. In cooling, it would sometimes go to 2 or 300% of the weight. In heating, it goes to less than nothing.

This only happens in the white powder form. But mass has never left. Losing weight when cooling the material (approaching absolute zero), and you have a superconductor.

A superconductor is a material that has a single wavelength in the sample, a single vibration or frequency, much like a laser. By definition, a superconductor does not allow any voltage potential to exist within it; it’s perfect amperage, but no voltage. To hook up wires with ordinary current to the superconductor and get the electrons off the wire, you need voltage. You have the tune the vibrational frequency of the electrons in the wire to that of the superconductors. And to get them off.

The electrons going into the superconductor have to pair, with a time forward electron with a time reverse electron. When they pair, they become light. Any amount of light can exist in the superconductor. It doesn’t reside in any space-time. The only way to prove it’s a superconductor is to measure a Meissner field. Non-polar field (only field of its kind). Superconductivity responds to magnetic fields. Earth’s magnetic field is larger.

A superconductor can see your thoughts in your brain. Different parts of your brain light up when you eat something sweet or something sour — it’s a superconductor that sees it.

When it goes to the white powder and loses 4/9th of its weight, it’s flowing light within it, in response to the earth’s magnetic field. And it flows so much current that it levitates 4/9th of its weight on the earth’s magnetic field. A human hand has sufficient amperage, that if you pass it under the sample, the material floats. It’s that sensitive to magnetic fields. All the eight precious metal elements can do this. Also Copper, Cobalt, and Nickel. So, I filed 11 patents.

In 1990, my uncle showed me the Time-Life Book, Secrets of the Alchemist. I was not interested in Alchemy; I wanted credibility in physics and chemistry. The book talks about a “white powder of gold”. The goal of the alchemist had been to make a “white powder of gold”. To make “the container of the light of life.” If you stand in its presence, you don’t age. If you partake of it, you live forever. I begrudgingly agreed to read the book

I have since read some 500 books on alchemy, alchemy history, and it all goes back to a man named Enoch. Thoth, Hermes, Trigeminus. Same man. Ascended by partaking of the white drops. He never died, instead ascended because he was so perfect.

I found a huge amount of research going on in treating cancer with precious elements. That the elements have been found interacting with a cell by a vibrational frequency or by a light transfer and have been correcting the DNA. Any alteration, any defect in the DNA is corrected by the precious elements. It perfects the cells of our bodies. But the element going into our bodies is not a metal, the element is not a heavy metal, it is an element. So there’s no heavy metal poisoning. You can eat any amount of this white flour, and it doesn’t hurt you. If you eat it, it just goes through your digestive system.

I took some brain tissue from a pig, and some from a cow, and analyzed it. They destroyed the organic and did a metals analysis. Over 5% of the brain tissue by dry matter weight was Rhodium and Iridium. But no one knows it because it can’t be directly measured. The elements are flowing the light of life in your body. The elements are in fact what the light is. There are four papers by the U.S. Naval Research that they have proved the cells communicate with each other by a process identical to superconductivity. But they can’t figure out the physical mechanism.

It is the stealth atoms. It’s the atoms in our bodies. However, no one knows they’re there because they don’t identify them by instrumental analysis. And the reason they don’t identify them is also in the literature. Since 1986, the top physicists in the world, at the Niels Bohr Institute, at Argonne National Laboratory, at Brookhaven… They have found that there is a group of elements in the center of the Periodic Table that go through this strange state of existence.

So most of these publications occurred between 1988 on, but my patents were filed first. What they have found is that the nucleus of these elements were deformed, went to a high spin state — what’s called high spin nuclei — and theoretically, these high spin nuclei should be superconductors because high spin nuclei pass energy from one atom to the next with no loss of energy.

This is what is in our bodies. This is what flows the light of life. And when you understand that a superconductor flows a single wavelength of light, but, in fact, the light is a null light, two ways that are mirror images of each other. There’s no wave — it appears to cancel, but the null wave is in fact, while not measurable directly, is what produces the aura around our bodies. The aura is the Meissner field of superconductivity.

In our bodies, we have all this junk DNA. There are 30 aspects of the DNA that nobody can figure out what it’s there for. We only use 15% of our brain. What’s the other 85% of it there for? Did we evolve a brain we don’t use? It’s as if we had, at one time, a higher state of enlightenment, and we have fallen into the state we exist in now.

In ancient Egypt, which I traced this back to, there’s a book, called The Egyptian Book of the Dead and the Papyrus of Ani, by Budge. This is the oldest book of the dead, from Old Kingdom Egypt. They found it, dating from about 3500 B.C.E., in the tomb of Pepi II. It says, “I am purified of all imperfections. What is it? I ascend like the golden hawk of Horus. What is it? I pass by the immortals without dying. What is it? I come before my father in Heaven. What is it?”

It goes on and on and on. It keeps asking this question, “What is it?”

The Hebrews worked in Egypt for many, many generations — they were the artisans and the metallurgists. When they left Egypt, Baalzelael, the goldsmith and Moses prepared the bread of the presence of God. He prepared the bread that the high priest partook of, the Melchizedek priest. The word in Hebrew that means “What is it?” is manna. The word, manna, literally translates, verbatim, into a question, “What is it?” If you don’t believe it, look in the Travels of Josephus. The very same words that were used in Old Kingdom Egypt, 3500 B.C. [Pepi II reigned 90 years from c. 2300 to 2210 (traditional dating), or 1720 to 1630 (Immanuel Velikovsky’s dating).]

These elements are naturally in your body. It’s primarily Rhodium and Iridium. Now the Bible says that Moses told the Hebrew people, “You have not kept the covenant, and so the manna is being taken from you. But it will come back in the end times. When we will be a nation of high priests, not an elect high priesthood.” This is the food, the light, you take in your body.

If you ask a Rabbi, have you ever heard of the white powder of gold, he’ll say yes, we’ve heard of it, but to our knowledge, no one has known how to make it since the destruction of the First Temple. The temple of Solomon. This knowledge has been lost. But it wasn’t completely lost, the high priests when they left the temple when it was destroyed, went out on the desert and organized a commune called Qumran. They were the Essenes. In The Dead Seas Scrolls Uncovered [Eisement and Wise] this in ancient times, when the white powder was mixed in water, was known as The Golden Tear from the Eye of Horus. It was called, “That which issues from the mouth of the creator.” The spittle. Not the word of God, but the spittle. Or the semen of the father in heaven. If you put the white powder in water, it doesn’t dissolve. It forms this gelatinous suspension and looks just like a vial of semen. Being a farmer, I know what semen looks like.

The symbolism of “prepare yourself like a bride in the bridal chamber”, purify and cleanse yourself, prepare yourself for the coming of the Father in heaven, to be inseminated by the father in heaven in the bridal chamber. To totally be regenerated, to be purified, to be cleansed. Every cell in your body will be taken back to the way it’s supposed to be, when you were a teenager or a child. It perfects the DNA. And it flows the light until you reach the point where the light body exceeds the physical body.

In ancient Egypt, they said you have a physical body you must feed to grow as it’s meant to be. If you don’t feed that child, he’ll never grow. He’ll never become the person he’s supposed to be. But you also have to feed the spirit body, you have to feed the ka, what they called it in ancient Egypt — so it can grow and become what it’s meant to be. And most of you aren’t feeding your ka. It’s sitting there like a little runt inside your body. And they said you feed it and feed it and feed it with the semen of the father in heaven, and it grows and grows and becomes more enlightened and more enlightened, and you reach the point where the light body exceeds the physical body. You light up the room when you walk in.

The gifts that go with this are: perfect telepathy, you can know good and evil when it’s in the room with you, you also can project your thoughts into someone else’s mind. You can levitate; you can walk on water because it’s flowing so much light within you that you don’t attract gravity. And when you understand that when you exclude all external magnetic fields, when you exclude gravity, you are no longer of this space-time. You become a fifth-dimensional being. You can think where you would like to be, and go there. Just disappear. You also have other attributes that they go into. You can heal by the laying on of hands, and can cleanse and resurrect the dead within two or three days after they died. You have so much energy that you can embrace people and bring light and energy back into them.

Sounds pretty far out. Most groups don’t receive this very well.

If this is really what this stuff does, then let’s use it. I haven’t achieved everything yet, but it miraculously has cured every disease that we’ve tested on thus far. Started with very incremental amounts of 2 mg (32,000 mg in an ounce), and have gone up to 50 mg — 50 mg over a period of 60 to 90 days, cures cancer, AIDS. It’s the light that corrects itself. You all know this.

Christ said to his disciples, “Don’t touch me, I don’t have on my earthly garments.” They asked, “When will we see you again?” He replied, “When you have prepared the proper food and have on your proper garments.” What is the proper food? It’s the food of the angels, the food of the gods, the manna, the “What is it?” And your proper garment is your garment of Or, your Meissner field (what science calls it). And literally, it’s about a thousand times what you have now.

The amazing thing about superconductors is that they don’t have to touch for their energy to flow from one superconductor to another. Electricity has to touch. Superconductors can sit at a distance from each other, as long as they are in resonant frequency with each other, they are One. They function as one. So when you have your perfect superconducting body, you’re not of this space-time. You are a light being, and your mind is one with other people’s minds. You literally know their thoughts, and they know your thoughts. You and they are literally of one mind, one heart, and this is science.

The Bible says that the man who will plant the golden tree of life, which in Hebrew is the ORME tree (the name of my patents — at the time I had no idea of the connection). When my cousin joined the Morman Church, she had to do their genealogy, and his great, great, great grandmother is Hanah DeVries, daughter of Christopher DeVries, brother of Claude DeVries [see reference 2 above, and Holy Blood, Holy Grail]. Nostradamus worked for the DeVries family, and Nostradamus prophesied that by 1999, the occult gold will be known to science.

The old enemy of religion, the old enemy of philosophy is science, but in fact, science will serve up the confirmation and science will be the one who brings this to the world.

Religion has tried to do this for two thousand years, and it’s failed miserably. The world is no darn good. People are no darn good. They’re greedy; they’re selfish. The Capitalist system has worn out, based on selfishness and greed. But Science can take this to the world in four or five years. Once it is accepted and understood by scientists, the breakthroughs will just be astronomical.

A basic analytical breakthrough. You can fill yourself with this light. In The Dead Sea Scrolls Uncovered, not only did the Qumran community have a metallurgical foundry in the middle of the city, but you also find out that the teacher of righteousness, this thing they were totally preoccupied with, wasn’t Moses or Christ. It says the High Priest swallows the teacher of righteousness. The TR is the holy spirit, the TR for those scientists is the light, the zero-point light that isn’t measurable. It is, in fact, the light, the god source within us. We know all things. We don’t have to read or study. We just know.

When your light body exceeds your material body, you don’t have to eat food. You can if you want, but you don’t have to. You have perfect telepathy. How much more could you ever be judged than for everyone to know your heart and your mind. Everything about you is known. No more hidden agendas, no more lies, no more deceit. Everything is known. And this is called the opening of the book of light. In Revelations, it says, “Blessed be the man who shall overcome, for he shall be given the hidden manna, the white stone of the purest kind upon which will be written a new name.” He will not be the same person. It’s encoded in your DNA waiting to be activated.

It says that at 1160 degrees, the white powder of gold fuses to form gold glass. It’s a transparent glass, just like window glass. And in Revelations, it says, “The streets of the New Jerusalem will be paved with gold of the purest light, as transparent as glass, and the foundations of New Jerusalem will be made with gold liken unto glass.”

This is the gold glass, the very basis of the New Jerusalem. The very basis of raising our self and our consciousness to this higher state. This highest light that will activate all of our DNA will cause us to use all of our brain again, and we will return again to the original state that we were created to be in. Before we fell to the sleeping existence we know now.

These elements are in all of the herbs, the herbal teas, and many of the vegetables you vegetarians are eating. You get them in small amounts. Through work, dedication, years of study and meditation, you can achieve similar results. But it is tough to be a Tibetan Monk. This is called the Keys of the Kingdom. You insert it, and turn it and… It isn’t the answer, but the way to the answer. But if you step through that door, that’s your decision. Nobody’s going to make you take it.

There are many people in this world that don’t want this to happen. But this is the New World Order, just not the one George Bush saw. It can be scary. But it is here. Every piece is now known to Science. The philosophical implications are immense.